Zobrazeno 1 - 10
of 168
pro vyhledávání: '"efflux pump inhibition"'
Autor:
Denick Amon, Prince Manu, Evelyn Asante-Kwatia, Priscilla Kolibea Mante, Cynthia Amaning Danquah, Lawrence Sheringham Borquaye, Edmund Ekuadzi
Publikováno v:
Scientific African, Vol 26, Iss , Pp e02382- (2024)
Tabernaemontana crassa is a native plant indigenous to Ghana which has garnered local recognition for its purported efficacy against ringworm, wounds, abscesses, and antibacterial infections. However, the antibacterial and resistance modifying effect
Externí odkaz:
https://doaj.org/article/5febbf8d8f7b4c27b5dd806709f1bc40
Autor:
Ergin Murat Altuner, Muhammet Çavuş, İzzet Şener, Merve Şenturan, Çiğdem Şahin, Nesrin Şener, Eda Altınöz, Merve Zurnacı, Mahmut Gür
Publikováno v:
Hittite Journal of Science and Engineering, Vol 10, Iss 2, Pp 99-116 (2023)
In this study, 1,3,4-thiadiazole derivatives were obtained from the reaction of benzophenone-4,4'-dicarboxylic acid and N-substitute-thiosemicarbazide compounds with each other. After the synthesis of the final products, some biological properties of
Externí odkaz:
https://doaj.org/article/450914302452406db7cbae3d45d5d484
C-1 Substituted isoquinolines potentiate the antimycobacterial activity of rifampicin and ethambutol
Autor:
Liam T. Martin, Eleanor D. Lamming, Arundhati Maitra, Parisa N. Mortazavi, Rebecca Roddan, John M. Ward, Sanjib Bhakta, Helen C. Hailes
Publikováno v:
Frontiers in Antibiotics, Vol 2 (2023)
IntroductionThe emergence of extensively drug-resistant strains of Mycobacterium tuberculosis threatens decades of progress in the treatment of a disease which remains one of the leading infectious causes of death worldwide. The development of novel
Externí odkaz:
https://doaj.org/article/b19c3d06f60449e4b8617a588c56b3ec
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Publikováno v:
Pathogens, Vol 12, Iss 6, p 853 (2023)
Plectranthus amboinicus (Indian borage) has been extensively studied for its medicinal properties, which can be exploited to develop new antimicrobial therapeutics. The current study investigated the effect of Plectranthus amboinicus leaf extracts on
Externí odkaz:
https://doaj.org/article/5769ba9a3cb04c2f99a2d97cd57dc3f3
Autor:
Mariana C. Almeida, Nikoletta Szemerédi, Fernando Durães, Solida Long, Diana I. S. P. Resende, Paulo Martins da Costa, Madalena Pinto, Gabriella Spengler, Emília Sousa
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 922 (2023)
Drug resistance is rising to alarming levels, constituting one of the major threats to global health. The overexpression of efflux pumps and the formation of biofilms constitute two of the most common resistance mechanisms, favoring the virulence of
Externí odkaz:
https://doaj.org/article/887c16dec5c64af9894bd3da2b4296c3
Autor:
Mariana C. Almeida, Nikoletta Szemerédi, Fernando Durães, Diana I. S. P. Resende, Paulo Martins da Costa, Madalena Pinto, Gabriella Spengler, Emília Sousa
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 43 (2022)
With antimicrobial resistance reaching critical levels worldwide, the development of new compounds that are effective against resistant bacterial pathogens or that can potentiate the effect of known antibiotics is an urgent need. The formation of bio
Externí odkaz:
https://doaj.org/article/ec5c025f1f5d425aaeb55f1339e20a27
Autor:
Jacques-Aurélien Sergent, Hilarion Mathouet, Christian Hulen, Pedro Lameiras, Marc Feuilloley, Abdelhakim Elomri, Nour-Eddine Lomri
Publikováno v:
Molecules, Vol 27, Iss 9, p 3030 (2022)
To develop new therapeutic molecules, it is essential to understand the biological effects and targets of clinically relevant compounds. In this article, we describe the extraction and characterization of two alkaloids from the roots of Isolona hexal
Externí odkaz:
https://doaj.org/article/1671c6b5e67d4fd78c21cac320b407f9
Publikováno v:
Pathogens; Volume 12; Issue 6; Pages: 853
Plectranthus amboinicus (Indian borage) has been extensively studied for its medicinal properties, which can be exploited to develop new antimicrobial therapeutics. The current study investigated the effect of Plectranthus amboinicus leaf extracts on
Autor:
Fernando Durães, Nikoletta Szemerédi, Decha Kumla, Madalena Pinto, Anake Kijjoa, Gabriella Spengler, Emília Sousa
Publikováno v:
Marine Drugs, Vol 19, Iss 9, p 475 (2021)
Marine-derived fungi constitute an interesting source of bioactive compounds, several of which exhibit antibacterial activity. These acquire special importance, considering that antimicrobial resistance is becoming more widespread. The overexpression
Externí odkaz:
https://doaj.org/article/c5867d9895bf4adc81774ea1411698de