Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer‐naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells

Autor: Efrosini Kokkoli, Huihui Kuang, Zachary Schneiderman, Ahmed M. Shabana, Jun Guo, Gabriella Russo, Denis Wirtz

Publikováno v: Bioengineering & Translational Medicine, Vol 6, Iss 1, Pp n/a-n/a (2021)
Bioengineering & Translational Medicine

Despite decades of research, there are few targeted treatment options available for triple negative breast cancer (TNBC), leaving chemotherapy, and radiation treatment regimes with poor response and high toxicity. Herein aptamer‐amphiphiles were sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9be884b9a5f167bb1878e17fc4d908
https://doaj.org/article/918d67ee925b425c89d61aae0377e799

Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer-naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells.

Autor: Kuang H; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA., Schneiderman Z; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA.; Department of Chemical and Biomolecular Engineering Johns Hopkins University Baltimore Maryland USA., Shabana AM; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy Cairo University Cairo Egypt., Russo GC; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA.; Department of Chemical and Biomolecular Engineering Johns Hopkins University Baltimore Maryland USA., Guo J; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA., Wirtz D; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA.; Department of Chemical and Biomolecular Engineering Johns Hopkins University Baltimore Maryland USA., Kokkoli E; Institute for NanoBioTechnology Johns Hopkins University Baltimore Maryland USA.; Department of Chemical and Biomolecular Engineering Johns Hopkins University Baltimore Maryland USA.

Publikováno v: Bioengineering & translational medicine [Bioeng Transl Med] 2020 Nov 10; Vol. 6 (1), pp. e10194. Date of Electronic Publication: 2020 Nov 10 (Print Publication: 2021).