Zobrazeno 1 - 10
of 2 320
pro vyhledávání: '"early-life adversity"'
Autor:
Raphaela J. Gaertner, Manuel Burkart, Louisa Richter, Pius Schnell, Matthias Finkhäuser, Elea S. C. Klink, Bernadette F. Denk, Maria Meier, Ulrike U. Bentele, Stella Wienhold, Katharina E. Kossmann, Jens C. Pruessner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract While Early Live Adversity (ELA) is a known risk factor for mental and physical diseases, the investigation into the mechanisms behind this connection is ongoing. In the present study, we investigated whether ELA blunts the relaxation respon
Externí odkaz:
https://doaj.org/article/36cc8e66c322453abe4a8d4e8cd8eff9
Autor:
Eleftheria G. Charalambous, Sophie B. Mériaux, Pauline Guebels, Claude P. Muller, Fleur A. D. Leenen, Martha M. C. Elwenspoek, Ines Thiele, Johannes Hertel, Jonathan D. Turner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Intense psychosocial stress during early life has a detrimental effect on health-disease balance in later life. Simultaneously, despite its sensitivity to stress, the developing microbiome contributes to long-term health. Following stress ex
Externí odkaz:
https://doaj.org/article/e5a6672b8abb493a84b3e6dba3e76595
Autor:
Hatty Lara, Melissa Nevarez-Brewster, Cori Manning, Matthew J. Reid, Stephanie H. Parade, Gina M. Mason, Darlynn M. Rojo-Wissar
Publikováno v:
Frontiers in Sleep, Vol 3 (2024)
Sleep disturbances are posited to play a key role in the development of poor mental and physical health outcomes related to early life adversity (ELA), in part through effects on brain development. Language development is critically important for hea
Externí odkaz:
https://doaj.org/article/65f692511be1422f8abb06b527e2a792
Autor:
Rachel Deanna Phillips
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100881- (2024)
Early experiences of stress and adversity are associated with blunted reward sensitivity and altered reward learning. Meanwhile, anhedonia is characterized by impairments in reward processing, including motivation, effort, and pleasure. Early life st
Externí odkaz:
https://doaj.org/article/7b41763d94cd47fba656ebbed169a3d7
Autor:
Sophia C. Levis, Matthew T. Birnie, Yiyan Xie, Noriko Kamei, Puja V. Kulkarni, Johanna S. Montesinos, Christina R. Perrone, Catherine M. Cahill, Tallie Z. Baram, Stephen V. Mahler
Publikováno v:
Addiction Neuroscience, Vol 13, Iss , Pp 100175- (2024)
Opioid use disorder (OUD) is associated with a history of early-life adversity (ELA), an association that is particularly strong in women. In a rodent model, we previously found that ELA enhances risk for opioid addiction selectively in females, but
Externí odkaz:
https://doaj.org/article/8d64dd9956d94e94af54816248959924
Autor:
Rachel Gilgoff, Summer Mengelkoch, Jorina Elbers, Krista Kotz, Arielle Radin, Isha Pasumarthi, Reanna Murthy, Sayantani Sindher, Nadine Burke Harris, George M. Slavich
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractAlthough dysregulated stress biology is becoming increasingly recognized as a key driver of lifelong disparities in chronic disease, we presently have no validated biomarkers of toxic stress physiology; no biological, behavioral, or cognitive
Externí odkaz:
https://doaj.org/article/ec53ec90604449009e4e84f659ebb297
Autor:
Vera N. Karlbauer, Jade Martins, Monika Rex-Haffner, Susann Sauer, Simone Roeh, Katja Dittrich, Peggy Doerr, Heiko Klawitter, Sonja Entringer, Claudia Buss, Sibylle M. Winter, Christine Heim, Darina Czamara, Elisabeth B. Binder
Publikováno v:
Neurobiology of Stress, Vol 33, Iss , Pp 100687- (2024)
DNA methylation in peripheral tissues may be a relevant biomarker of risk for developing mental disorders after exposure to early life adversity. Genes involved in HPA axis regulation, such as FKBP5, might play a key role. In this study, we aimed to
Externí odkaz:
https://doaj.org/article/9029532bc4814b2abb45b68a31406752
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 6, Pp 100362- (2024)
Background: Exposure to adversity, including unpredictable environments, during early life is associated with neuropsychiatric illness in adulthood. One common factor in this sequela is anhedonia, the loss of responsivity to previously reinforcing st
Externí odkaz:
https://doaj.org/article/927168912dfe4bdfbcceae799c48a678
Autor:
Amanda A. Miller, Motohiro Nakajima, Briana N. DeAngelis, Dorothy K. Hatsukami, Mustafa al'Absi
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract Early life adversity (ELA) is associated with earlier initiation and maintenance of tobacco smoking and with a greater risk of subsequent relapse. There is growing evidence that appetite hormones, including peptide YY (PYY), which modulates
Externí odkaz:
https://doaj.org/article/4c909cabb73545d9a425d1d4601a5eaa
Publikováno v:
Developmental Cognitive Neuroscience, Vol 69, Iss , Pp 101437- (2024)
Addressing the tremendous burden of early-life adversity requires constructive dialogues between scientists and policy makers to improve population health. Whereas dialogues focused on several aspects of early-life adversity have been initiated, disc
Externí odkaz:
https://doaj.org/article/8030c4421ead4782821cdbeb980b2b96