eIF3f Mediates SGOC Pathway Reprogramming by Enhancing Deubiquitinating Activity in Colorectal Cancer

Autor: Qihao Pan, Fenghai Yu, Huilin Jin, Peng Zhang, Xiaoling Huang, Jingxuan Peng, Xiaoshan Xie, Xiangli Li, Ning Ma, Yue Wei, Weijie Wen, Jieping Zhang, Boyu Zhang, Hongyan Yu, Yuanxun Xiao, Ran‐yi Liu, Qingxin Liu, Xiangqi Meng, Mong‐Hong Lee

Publikováno v: Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)

Abstract Numerous studies have demonstrated that individual proteins can moonlight. Eukaryotic Initiation translation factor 3, f subunit (eIF3f) is involved in critical biological functions; however, its role independent of protein translation in re

Externí odkaz: https://doaj.org/article/cccac63897454c798c9a4946d259ceb9

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Targeting eIF3f Suppresses the Growth of Prostate Cancer Cells by Inhibiting Akt Signaling

Autor: Li J, Yu W, Ge J, Zhang J, Wang Y, Wang P, Shi G

Publikováno v: OncoTargets and Therapy, Vol Volume 13, Pp 3739-3750 (2020)

Junhong Li,* Wandong Yu,* Jianchao Ge, Jun Zhang, Yang Wang, Pengyu Wang, Guowei Shi Department of Urology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai 200240, People’s Republic of China*These authors contributed equally to this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::39a7e73928948a2cd9f9b59719f98bc3
https://www.dovepress.com/targeting-eif3f-suppresses-the-growth-of-prostate-cancer-cells-by-inhi-peer-reviewed-article-OTT

EIF3F-related neurodevelopmental disorder: refining the phenotypic and expanding the molecular spectrum

Autor: H��ffmeier, Ulrike, Kraus, Cornelia, Reuter, Miriam S, Uebe, Steffen, Abbott, Mary-Alice, Ahmed, Syed A, Rawson, Kristyn L, Barr, Eileen, Li, Hong, Bruel, Ange-Line, Faivre, Laurence, Tran Mau-Them, Fr��d��ric, Botti, Christina, Brooks, Susan, Burns, Kaitlyn, Ward, D Isum, Dutra-Clarke, Marina, Martinez-Agosto, Julian A, Lee, Hane, Nelson, Stanley F, Zacher, Pia, Abou Jamra, Rami, Kl��ckner, Chiara, McGaughran, Julie, Kohlhase, J��rgen, Schuhmann, Sarah, Moran, Ellen, Pappas, John, Raas-Rothschild, Annick, Sacoto, Maria J Guillen, Henderson, Lindsay B, Palculict, Timothy Blake, Mullegama, Sureni V, Zghal Elloumi, Houda, Reich, Adi, Schrier Vergano, Samantha A, Wahl, Erica, Reis, Andr��, Zweier, Christiane

Publikováno v: Orphanet Journal of Rare Diseases
Hüffmeier, Ulrike; Kraus, Cornelia; Reuter, Miriam S; Uebe, Steffen; Abbott, Mary-Alice; Ahmed, Syed A; Rawson, Kristyn L; Barr, Eileen; Li, Hong; Bruel, Ange-Line; Faivre, Laurence; Tran Mau-Them, Frédéric; Botti, Christina; Brooks, Susan; Burns, Kaitlyn; Ward, D Isum; Dutra-Clarke, Marina; Martinez-Agosto, Julian A; Lee, Hane; Nelson, Stanley F; ... (2021). EIF3F-related neurodevelopmental disorder: refining the phenotypic and expanding the molecular spectrum. Orphanet journal of rare diseases, 16(1), p. 136. BioMed Central 10.1186/s13023-021-01744-1

Background An identical homozygous missense variant in EIF3F, identified through a large-scale genome-wide sequencing approach, was reported as causative in nine individuals with a neurodevelopmental disorder, characterized by variable intellectual d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c030976d24aa0e2895bd4c27349a1a1
https://opus4.kobv.de/opus4-fau/files/17672/s13023-021-01744-1.pdf

A cyclin-dependent kinase, CDK11/p58, represses cap-dependent translation during mitosis

Autor: Oh Sung Kwon, Sihyeon An, Jinbae Yu, Sung Key Jang

Publikováno v: Cellular and Molecular Life Sciences

During mitosis, translation of most mRNAs is strongly repressed; none of the several explanatory hypotheses suggested can fully explain the molecular basis of this phenomenon. Here we report that cyclin-dependent CDK11/p58—a serine/threonine kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a3be0a2d26a9b507efc54a7d0e9d10
https://pubmed.ncbi.nlm.nih.gov/32030451