Fungal effector SIB1 of Colletotrichum orbiculare has unique structural features and can suppress plant immunity in Nicotiana benthamiana

Autor: Jun-ichi Kurita, Noriyoshi Isozumi, Ru Zhang, Suthitar Singkaravanit-Ogawa, Yoshitaka Takano, Shinya Ohki, Masashi Mori, Pamela Gan, Ken Shirasu, Tomohiro Imamura, Ryuta Okuta

Publikováno v: The Journal of Biological Chemistry

Fungal plant pathogens secrete virulence-related proteins, called effectors, to establish host infection; however, the details are not fully understood yet. Functional screening of effector candidates using Agrobacterium-mediated transient expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6dc53745496cd59eb53d68220bf094
http://hdl.handle.net/2433/276201

Monitoring cellular redox dynamics using newly developed BRET-based redox sensor proteins

Autor: Nae Fu, Ken-ichi Wakabayashi, Shungo Nakamura, Kumiko Kondo, Toru Hisabori, Kazunori Sugiura

Publikováno v: The Journal of Biological Chemistry

Reactive oxygen species are key factors that strongly affect the cellular redox state and regulate various physiological and cellular phenomena. To monitor changes in the redox state, we previously developed fluorescent redox sensors named Re-Q, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becef2d680d3fc03b5ca82792cac9340
http://europepmc.org/articles/PMC8487062

A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide

Autor: Becky Provinciael, Eberhard Krause, Claudia Rutz, Dominique Schols, Heike Stephanowitz, Joren Stroobants, Eva Pauwels, Enno Hartmann, Kurt Vermeire, Ralf Schülein

Publikováno v: Molecular & Cellular Proteomics : MCP

Cyclotriazadisulfonamide (CADA) inhibits the cotranslational translocation of type I integral membrane protein human CD4 (huCD4) across the endoplasmic reticulum in a signal peptide (SP)–dependent way. Previously, sortilin was identified as a secon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fa4c29ffd398e3d63aa5ece3f08763
https://pubmed.ncbi.nlm.nih.gov/34481949

The C-Mannosylome of Human Induced Pluripotent Stem Cells Implies a Role for ADAMTS16 C-Mannosylation in Eye Development

Autor: Aleksandra Shcherbakova, Karsten Cirksena, Joachim Wittbrodt, Falk F. R. Buettner, Roman Sakson, Lars R. Jensen, Thomas Ruppert, Daniel Todt, Andreas W. Kuss, Alina Friedrich, Stefan Weiss, Hermann J. Hütte, Hans Bakker, Thomas Thumberger

Publikováno v: Molecular & Cellular Proteomics : MCP

C-mannosylation is a modification of tryptophan residues with a single mannose and can affect protein folding, secretion, and/or function. To date, only a few proteins have been demonstrated to be C-mannosylated, and studies that globally assess prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7dcfa5ab5c34fd0ed0c4709b4ea4419
https://pubmed.ncbi.nlm.nih.gov/33975020

Quantitative analysis of the formation of nucleoprotein complexes between HIV-1 Gag protein and genomic RNA using transmission electron microscopy

Autor: Durand, Stéphanie, Seigneuret, Florian, Burlaud-Gaillard, Julien, Lemoine, Roxane, Tassi, Marc-Florent, Moreau, Alain, Mougel, Marylène, Roingeard, Philippe, Tauber, Clovis, de Rocquigny, Hugues

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 298 (1), pp.101500. ⟨10.1016/j.jbc.2021.101500⟩
The Journal of Biological Chemistry

International audience; In HIV, the polyprotein precursor Gag orchestrates the formation of the viral capsid. In the current view of this viral assembly, Gag forms low-order oligomers that bind to the viral genomic RNA triggering the formation of hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0b28f1cd1e4c010e4ad7c9816ecb3aee
https://hal.umontpellier.fr/hal-03681176