Zobrazeno 1 - 10
of 154
pro vyhledávání: '"dynamin-related protein 1 (DRP1)"'
Autor:
Tiantian Tian, Huan Pang, Xinyue Li, Kai Ma, Tianxiang Liu, Jiali Li, Zhixuan Luo, Meng Li, Qiaohong Hou, Huifang Hao, Jianfei Dong, Haiying Du, Xiaomei Liu, Zhiwei Sun, Chao Zhao, Xiuling Song, Minghua Jin
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 272, Iss , Pp 116050- (2024)
Silica nanoparticles (SiNPs) are widely used in the biomedical field and can enter the central nervous system through the blood-brain barrier, causing damage to hippocampal neurons. However, the specific mechanism remains unclear. In this experiment,
Externí odkaz:
https://doaj.org/article/92d683378c344577ad1d428f308846ec
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 10, Pp 1522-1529 (2023)
Objective To explore mechanism of prohibitin 2(PHB2) inhibition on the apoptosis of non-small cell lung cancer cell line A549. Methods For stable knockdown of PHB2, A549 strain was infected with lentiviruses. A549 cells with PHB2 depletion were incub
Externí odkaz:
https://doaj.org/article/7be9ecdf97c442cd883e85783f44a80e
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-27 (2023)
Abstract Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged following ischemia and hypoxia. Dynamin-related protein 1 (Drp1) regulates mitochondrial qualit
Externí odkaz:
https://doaj.org/article/cb36bd9424824ceda312bb1b64dc23d8
Autor:
Yafei Zhang, Bingqian Yang, Chengwei Tu, Yifan Ping, Shuhong Chen, Tong Wu, Zheyu Zhao, Yixin Mao, Zhan Yang, Zelin Cao, Jianmin Li, Kate Huang, Xi Ding, Gang Wu, Peng Zou, Zhennan Deng, Xiaoyu Sun
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited.
Externí odkaz:
https://doaj.org/article/93397a6b0bf942b6ac4c2b59107da2c4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/5bd50a8b053149d9aefe69c151cc0ac3
Autor:
Mankun Wei, Uli Nurjanah, Juan Li, Xinxin Luo, Rendy Hosea, Yanjun Li, Jianting Zeng, Wei Duan, Guanbin Song, Makoto Miyagishi, Vivi Kasim, Shourong Wu
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Cancer stem cells (CSCs) are associated with tumor progression, recurrence, and therapeutic resistance. To maintain their pool while promoting tumorigenesis, CSCs divide asymmetrically, producing a CSC and a highly proliferative, more differ
Externí odkaz:
https://doaj.org/article/9db1593e56744d608075d0d18b108172
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pulmonary arterial hypertension (PAH) is an orphan disease of the cardiopulmonary unit that reflects an obstructive pulmonary vasculopathy and presents with hypertrophy, inflammation, fibrosis, and ultimately failure of the right ventricle (RVF). Des
Externí odkaz:
https://doaj.org/article/64554359d0784373a842712ef55189d2
Autor:
Stephen L. Archer, Asish Dasgupta, Kuang-Hueih Chen, Danchen Wu, Kaushal Baid, John E. Mamatis, Victoria Gonzalez, Austin Read, Rachel ET. Bentley, Ashley Y. Martin, Jeffrey D. Mewburn, Kimberly J. Dunham-Snary, Gerald A. Evans, Gary Levy, Oliver Jones, Ruaa Al-Qazazi, Brooke Ring, Elahe Alizadeh, Charles CT. Hindmarch, Jenna Rossi, Patricia DA. Lima, Darryl Falzarano, Arinjay Banerjee, Che C. Colpitts
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102508- (2022)
Rationale: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 pneumonia. We hypothesize that SARS-CoV-2 causes alveolar injury and hypoxemia by damaging mitochondria in airway epithelial cells (AEC) and pulmonary artery smoo
Externí odkaz:
https://doaj.org/article/e159da1d54f348208fca210ce85dc53f
Akademický článek
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