Zobrazeno 1 - 10
of 1 870
pro vyhledávání: '"dual-targeting"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9121-9143 (2024)
Yanan Huang,1,* Yunfeng Wang,2,* Tianyu Zheng,1,* Shuang Nie,1 Yanli Wang,3 Hui Shen,1 Fengfeng Mo1 1Department of Naval Nutrition and Food Hygiene, Faculty of Navy Medicine, Naval Medical University, Shanghai, People’s Republic of Chin
Externí odkaz:
https://doaj.org/article/48127cf3b1c74377bafbcaa70a919a4e
Autor:
Shang Chen, Yan He, Xin Huang, Yao Shen, Qingshuang Zou, Gun Yang, Li Fu, Quan Liu, Dixian Luo
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Tumor-associated macrophages (TAMs) are a promising target for cancer immunotherapy, but delivering therapeutic agents to TAMs within the tumor microenvironment (TME) is challenging. In this study, a photosensitive, dual-targeting nanopartic
Externí odkaz:
https://doaj.org/article/326590191cff4ad8b056694ab5be7f7e
Autor:
Ruogu Qi, Shanshan Wang, Jiayi Yu, Tianming Lu, Zhiqiang Bi, Weibo Liu, Yuanyuan Guo, Yong Bian, Jianliang Shen, Xuesong Zhang, Wenhao Hu
Publikováno v:
Engineering, Vol 36, Iss , Pp 178-192 (2024)
Multiple myeloma (MM) is the second most prevalent hematological malignancy. Current MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic efficacy. This study addressed these limitations through the development of a po
Externí odkaz:
https://doaj.org/article/13a6ddea0c2c4f81b45d1ccb5fbb0539
Autor:
Hong Guo, Xia Li, Dengxuan Mao, Hong Wang, Liangyin Wei, Ding Qu, Xiaoying Qin, Xiaoqi Li, Yuping Liu, Yan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract The insufficient abundance and weak activity of tumour-infiltrating lymphocytes (TILs) are two important reasons for the poor efficacy of PD-1 inhibitors in hepatocellular carcinoma (HCC) treatment. The combined administration of tanshinone
Externí odkaz:
https://doaj.org/article/20208845e30440a29984cf1059067259
Autor:
Simona Camorani, Alessandra Caliendo, Elena Morrone, Lisa Agnello, Matteo Martini, Monica Cantile, Margherita Cerrone, Antonella Zannetti, Massimo La Deda, Monica Fedele, Loredana Ricciardi, Laura Cerchia
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Based on the established role of cancer-stroma cross-talk in tumor growth, progression and chemoresistance, targeting interactions between tumor cells and their stroma provides new therapeutic approaches. Dual-targeted nanotherape
Externí odkaz:
https://doaj.org/article/f2b432946e7242598a6cb68ee4977e6a
Publikováno v:
Pharmaceutical Science Advances, Vol 2, Iss , Pp 100046- (2024)
Patients with advanced hepatocellular carcinoma (HCC) are not sensitive to sorafenib (SOR), therefore, combination therapy is required. In this study, an improved thin-film dispersion and post-insertion anchoring technique was utilized to construct a
Externí odkaz:
https://doaj.org/article/8b12dfb9ac414d6d9d55cb6e67f740ac
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractColorectal cancer (CRC) is one of the most common cancers worldwide. Nowadays, owing to the complex mechanism of tumorigenesis, simultaneous inhibition of multiple targets is an important anticancer strategy. Recent studies have demonstrated
Externí odkaz:
https://doaj.org/article/c0259a46e9354907be2849c602177314
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractLiver cancer exhibits a high degree of heterogeneity and involves intricate mechanisms. Recent research has revealed the significant role of histone lysine methylation and acetylation in the epigenetic regulation of liver cancer development.
Externí odkaz:
https://doaj.org/article/22b604f5c6384211ba65b8aee18b01df
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Here, a separation‐free and label‐free portable aptasensor is developed for rapid and sensitive analysis of tumor‐derived exosomes (TEXs). It integrated a parallel rolling circle amplification (RCA) reaction, selective binding of metal
Externí odkaz:
https://doaj.org/article/18975f99e7fd4bd4b89c88e992f3908f