The progress of research into pseudophosphatases

Autor: Deqiang Liu, Yiming Zhang, Hui Fang, Jinxiang Yuan, Lizhen Ji

Publikováno v: Frontiers in Public Health, Vol 10 (2022)

Pseudophosphatases are a class of phosphatases that mutate at the catalytically active site. They play important parts in many life processes and disorders, e.g., cell apoptosis, stress reaction, tumorigenesis, axon differentiation, Charcot-Marie-Too

Externí odkaz: https://doaj.org/article/2ca8cef245c74d3d8e4a5073d9cbffad

Pseudophosphatases as Regulators of MAPK Signaling

Autor: Shantá D. Hinton, Emma Marie Wilber Hepworth

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12595, p 12595 (2021)
International Journal of Molecular Sciences

Mitogen-activated protein kinase (MAPK) signaling pathways are highly conserved regulators of eukaryotic cell function. These enzymes regulate many biological processes, including the cell cycle, apoptosis, differentiation, protein biosynthesis, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33ffbe6b2bd656e3382b11e3193b78a
https://www.mdpi.com/1422-0067/22/22/12595

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Dual-specificity MAP kinase phosphatases as targets of cancer treatment

Autor: Pablo Rios, Céline Tárrega, Rocío Cejudo-Marín, Rafael Pulido, Carlos Romá-Mateo, Caroline E. Nunes-Xavier, Lydia Tabernero

Publikováno v: Scopus-Elsevier
Anti-Cancer Agents in Medicinal Chemistry
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
University of Manchester-PURE
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname

The protein tyrosine phosphatase family (PTP) contains a group of dual-specificity phosphatases (DUSPs) that regulate the activivity of MAP kinases (MAPKs), which are key effectors in the control of cell growth and survival in physiological and patho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc083c38c972deb467ce723c959f5d7d
http://www.scopus.com/inward/record.url?eid=2-s2.0-79953018680&partnerID=MN8TOARS