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pro vyhledávání: '"du145"'
Autor:
Maysa Alhawamdeh, Wafa Hourani, Samir Al-Taweel, Salah Al-Trawneh, Majd Abu Raideh, Ayesha Masood
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101785- (2024)
Five novel 8-nitrociprofloxacin-1,2,3-triazole conjugates(9a-e) were synthesized via 1,3-dipolar cycloaddition reaction, by reacting ethyl 1-cyclopropyl-6-fluoro-8-nitro-4-oxo-7-(4-(3-oxobutanoyl) piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate(7)
Externí odkaz:
https://doaj.org/article/aaea78b2752a44978e03ad5b555c68a4
Autor:
Talib Hussain, Ahmed Alafnan, Ibrahim Abdullah Almazni, Nawal Helmi, Afrasim Moin, Hanadi M. Baeissa, Amir Mahgoub Awadelkareem, AbdElmoneim O. Elkhalifa, Tahani Bakhsh, Abdulrahman Alzahrani, Rashed Mohammed Alghamdi, Mohammad Khalid, Rohit Kumar Tiwari, Syed Mohd Danish Rizvi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
At the molecular level, several developmental signaling pathways, such as Wnt/β-catenin, have been associated with the initiation and subsequent progression of prostate carcinomas. The present report elucidated the anti-cancerous attributes of an an
Externí odkaz:
https://doaj.org/article/29e75e5be7aa4e4084ab2555118cc9c5
Autor:
Gloria Cecilia Galvan, Nadine A. Friedrich, Sanjay Das, James P. Daniels, Sara Pollan, Shweta Dambal, Ryusuke Suzuki, Sergio E. Sanders, Sungyong You, Hisashi Tanaka, Yeon-Joo Lee, Wei Yuan, Johann S. de Bono, Irina Vasilevskaya, Karen E. Knudsen, Michael R. Freeman, Stephen J. Freedland
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWe previously reported that cholesterol homeostasis in prostate cancer (PC) is regulated by 27-hydroxycholesterol (27HC) and that CYP27A1, the enzyme that converts cholesterol to 27HC, is frequently lost in PCs. We observed that restoring
Externí odkaz:
https://doaj.org/article/ec60d6dd2eac4bd18a56190427b615e9
Autor:
Alema Dedić, Hurija Džudžević-Čančar, Tatjana Stanojković, Marin Roje, Ana Damjanović, Amra Alispahić, Anesa Jerković-Mujkić
Publikováno v:
Kemija u Industriji, Vol 72, Iss 5-6, Pp 323-330 (2023)
Sloe (Prunus spinosa L.) extracts are a good source of natural bioactive compounds, including phytosterols. Phytosterols are known to be applied in the treatment of various prostate diseases. The in vitro antiproliferative activity of sloe ethanolic
Externí odkaz:
https://doaj.org/article/6eaf443885664857bc574de4ca598641
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20662- (2023)
The WASF3 gene promotes cancer cell invasion and metastasis, and genetic inactivation leads to suppression of metastasis. To identify small molecules that might interfere with WASF3 function, we performed an in silico docking study to the regulatory
Externí odkaz:
https://doaj.org/article/c51ff440a0444efb90fbeb72ef786374
Akademický článek
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Akademický článek
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Autor:
R. R. Khalikov, D. D. Gromenko, S. Sh. Galimova, K. V. Danilko, I. D. Gromenko, Sh. N. Galimov, P. F. Litvitsky
Publikováno v:
Креативная хирургия и онкология, Vol 12, Iss 2, Pp 118-122 (2022)
Background. Melittin is a major constituent of honeybee venom and comprises a water-soluble surfactant peptide with cytolytic effects potentially applicable in anticancer therapy. We evaluated the impact of melittin from Bashkir honeybee (Apis mellif
Externí odkaz:
https://doaj.org/article/dadd82e66e1a4af492065b1b21aad9f8
Autor:
Marchetti Carla
Publikováno v:
Biomolecular Concepts, Vol 13, Iss 1, Pp 156-163 (2022)
Calcium signaling controls a large variety of cell functions, including proliferation and apoptosis, and plays a major role in neoplastic transformation. Prostate cancer (PCa) is one of the most common malignancies in men. The transition to castratio
Externí odkaz:
https://doaj.org/article/babf18b67da5456b8a9feb446c1884d3