Novel transforming growth factor beta transcriptional targets in adult lung fibroblasts indentified by microarray analysis

Autor: Renzoni, EA, Abraham, DJ, Shi-Wen, X, Howat, S, Bou-Gharios, G, Wells, AU, Veeraraghavan, S, Nicholson, AG, Denton, C, Pearson, JD, Black, C, Welsh, KI, du Bois, RM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a9b3a4abb8737162c71517f093941d30
https://ora.ox.ac.uk/objects/uuid:66bd7507-38b0-4c9a-b1d2-3bcf9aa96c56

All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials

Autor: Williamson Z. Bradford, Steven A. Sahn, Paul W. Noble, Talmadge E. King, Steven D. Nathan, Jonathan A. Leff, Dominique Valeyre, du Bois Rm, Ulrich Costabel, Carlo Albera

Publikováno v: American journal of respiratory and critical care medicine. 189(7)

FVC has emerged as a standard primary endpoint in clinical trials evaluating novel therapies for patients with idiopathic pulmonary fibrosis (IPF). However, it has recently been proposed that all-cause mortality or a composite comprised of all-cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9a03f064c16e7431d875069e83bfd2
https://pubmed.ncbi.nlm.nih.gov/24684356

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

Autor: Fingerlin, TE, Murphy, E, Zhang, W, Peljto, AL, Brown, KK, Steele, MP, Loyd, JE, Cosgrove, GP, Lynch, D, Groshong, S, Collard, HR, Wolters, PJ, Bradford, WZ, Kossen, K, Seiwert, SD, Du Bois, RM, Garcia, CK, Devine, MS, Gudmundsson, G, Isaksson, HJ, Kaminski, N, Zhang, Y, Gibson, KF, Lancaster, LH, Cogan, JD, Mason, WR, Maher, TM, Molyneaux, PL, Wells, AU, Moffatt, MF, Selman, M, Pardo, A, Kim, DS, Crapo, JD, Make, BJ, Regan, EA, Walek, DS, Daniel, JJ, Kamatani, Y, Zelenika, D, Smith, K, McKean, D, Pedersen, BS, Talbert, J, Kidd, RN, Markin, CR, Beckman, KB, Lathrop, M, Schwarz, MI, Schwartz, DA

Publikováno v: Fingerlin, TE; Murphy, E; Zhang, W; Peljto, AL; Brown, KK; Steele, MP; et al.(2013). Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nature Genetics, 45(6), 613-620. doi: 10.1038/ng.2609. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2498k0ks

We performed a genome-wide association study of non-Hispanic, white individuals with fibrotic idiopathic interstitial pneumonias (IIPs; n = 1,616) and controls (n = 4,683), with follow-up replication analyses in 876 cases and 1,890 controls. We confi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c067df026de7c019b34b2a4ab64e6af3
http://www.escholarship.org/uc/item/2498k0ks

CC chemokine receptor 5 gene polymorphisms in beryllium disease

Autor: du Bois Rm, Eb Gottschall, May Gillespie, Lori J. Silveira, Lisa A. Maier, Ki Welsh, Ls Newman, Hiroe Sato, Paolo Spagnolo

CC chemokine receptor 5 (CCR5) is expressed on type-1 T-helper cells, which are involved in the pathogenesis of the granulomatous lung disease chronic beryllium disease (CBD). CCR5 gene (CCR5) polymorphisms are associated with sarcoidosis severity. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2910892e1bf78f22c3e84abf352adc21
https://europepmc.org/articles/PMC3061572/

Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis

Autor: Carulli, Mt, Spagnolo, Paolo, Fonseca, C, Welsh, Ki, du Bois RM, Black, Cm, Denton, C. P.

Publikováno v: The Journal of rheumatology. 35(5)

To validate the reported association between CC chemokine ligand 2 (CCL2) -2518 G single nucleotide polymorphism and systemic sclerosis (SSc) in a much larger cohort of patients. We also performed subgroup analysis to test the hypothesis that CCL2 va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7ffa4bd668e32e16d573cd976ea18085
https://pubmed.ncbi.nlm.nih.gov/18381789