Novel transforming growth factor beta transcriptional targets in adult lung fibroblasts indentified by microarray analysis

Autor: Renzoni, EA, Abraham, DJ, Shi-Wen, X, Howat, S, Bou-Gharios, G, Wells, AU, Veeraraghavan, S, Nicholson, AG, Denton, C, Pearson, JD, Black, C, Welsh, KI, du Bois, RM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a9b3a4abb8737162c71517f093941d30
https://ora.ox.ac.uk/objects/uuid:66bd7507-38b0-4c9a-b1d2-3bcf9aa96c56

All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials

Autor: Williamson Z. Bradford, Steven A. Sahn, Paul W. Noble, Talmadge E. King, Steven D. Nathan, Jonathan A. Leff, Dominique Valeyre, du Bois Rm, Ulrich Costabel, Carlo Albera

Publikováno v: American journal of respiratory and critical care medicine. 189(7)

FVC has emerged as a standard primary endpoint in clinical trials evaluating novel therapies for patients with idiopathic pulmonary fibrosis (IPF). However, it has recently been proposed that all-cause mortality or a composite comprised of all-cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9a03f064c16e7431d875069e83bfd2
https://pubmed.ncbi.nlm.nih.gov/24684356

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

Autor: Fingerlin, TE, Murphy, E, Zhang, W, Peljto, AL, Brown, KK, Steele, MP, Loyd, JE, Cosgrove, GP, Lynch, D, Groshong, S, Collard, HR, Wolters, PJ, Bradford, WZ, Kossen, K, Seiwert, SD, Du Bois, RM, Garcia, CK, Devine, MS, Gudmundsson, G, Isaksson, HJ, Kaminski, N, Zhang, Y, Gibson, KF, Lancaster, LH, Cogan, JD, Mason, WR, Maher, TM, Molyneaux, PL, Wells, AU, Moffatt, MF, Selman, M, Pardo, A, Kim, DS, Crapo, JD, Make, BJ, Regan, EA, Walek, DS, Daniel, JJ, Kamatani, Y, Zelenika, D, Smith, K, McKean, D, Pedersen, BS, Talbert, J, Kidd, RN, Markin, CR, Beckman, KB, Lathrop, M, Schwarz, MI, Schwartz, DA

Publikováno v: Fingerlin, TE; Murphy, E; Zhang, W; Peljto, AL; Brown, KK; Steele, MP; et al.(2013). Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nature Genetics, 45(6), 613-620. doi: 10.1038/ng.2609. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2498k0ks

We performed a genome-wide association study of non-Hispanic, white individuals with fibrotic idiopathic interstitial pneumonias (IIPs; n = 1,616) and controls (n = 4,683), with follow-up replication analyses in 876 cases and 1,890 controls. We confi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c067df026de7c019b34b2a4ab64e6af3
http://www.escholarship.org/uc/item/2498k0ks

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

Autor: King TE Jr, Albera, C, Bradford, Wz, Costabel, U, Hormel, P, Lancaster, L, Noble, Pw, Sahn, Sa, Szwarcberg, J, Thomeer, M, Valeyre, D, du Bois RM, INSPIRE Study Group, Agostini, Carlo, Allen, J, Anzueto, A, Behr, J, Bonnet, R, Buhl, R, Burge, S, Chan, A, Chan, C, Chanez, P, Chapman, J, Cordier, J, Covelli, H, Crimi, N, de Andrade, J, Delaval, P, Dromer, C, Egan, J, Enelow, R, Ettinger, N, Flaherty, K, Floreani, A, Frankel, S, Frost, A, Gibson, K, Glassberg, M, Gottfried, M, Harari, S, Helmersen, D, Hollingsworth, H, Horton, M, Jennings, J, Kallay, M, Lasky, J, Lee, A, Leonard, C, Lorch, D, Lynch, J, Mageto, Y, Mette, S, Millar, A, Morell Brotad, F, Müller Quernheim, J, Nathan, S, Noth, I, Padilla, M, Poletti, V, Raghu, G, Richeldi, L, Robbins, M, Rolf, J, Roman, J, Rosen, G, Rottoli, P, Saltini, C, Schaberg, T, Schaumberg, T, Scholand, M, Schönfeld, N, Sharma, S, Simonelli, P, Steele, M, Sussman, R, Tino, G, Vogelmeier, C, Wallaert, B, Wells, A, Wencel, M, Wesselius, L, Whelan, T, Wilcox, P, Wolters, P, Xaubet, A, Zisman, D.

Publikováno v: Lancet (London, England). 374(9685)

Summary Background Idiopathic pulmonary fibrosis is a fatal disease for which no effective treatment exists. We assessed whether treatment with interferon gamma-1b improved survival compared with placebo in patients with idiopathic pulmonary fibrosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021c04f78ffe0b273f7a8291394121aa
https://pubmed.ncbi.nlm.nih.gov/19570574

A Functional polymorphism in the CTGF promoter is associated with risk of systemic sclerosis

Autor: Fonseca, C, Lindahl, Ge, Ponticos, M, Sestini, P, Renzoni, Ea, Holmes, Am, Spagnolo, Paolo, Pantelidis, P, Leoni, P, Mchugh, N, Stock, C, Shi Wen, X, Denton, Cp, Black, Cm, Welsh, Ki, du Bois RM, Abraham, Dj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3674::9d2586b3a6c30e0253ec096beefc5f4e
https://hdl.handle.net/11380/983392