Zobrazeno 1 - 10
of 60
pro vyhledávání: '"dsDNA, double stranded DNA"'
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Autor:
Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfeee0d62636797c4da5264a84ca925
https://doi.org/10.1016/j.apsb.2021.01.001
https://doi.org/10.1016/j.apsb.2021.01.001
Autor:
N.V. Vorobjeva
Publikováno v:
Moscow University Biological Sciences Bulletin
— Neutrophils are the “first line” of defense against pathogens in the locus of inflammation, where they use effector functions such as phagocytosis, degranulation, and formation of reactive oxygen species (ROS). In 2004, Artuto Zychlinsky char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01f41f8c5f92ac886ffa0590ea714b0
http://europepmc.org/articles/PMC7869772
http://europepmc.org/articles/PMC7869772
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2272-2298 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Multiple cancer immunotherapies including chimeric antigen receptor T cell and immune checkpoint inhibitors (ICIs) have been successfully developed to treat various cancers by motivating the adaptive anti-tumor immunity. Particularly, the checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c604607610f05b2d37da5b2cce00382
http://www.sciencedirect.com/science/article/pii/S2211383519316946
http://www.sciencedirect.com/science/article/pii/S2211383519316946
Autor:
Cuong V. Nguyen, Anupama Shahane, Misha Rosenbach, Meliha Skaljic, Jeff Greenblatt, Kathleen Degnan, Xiaowei Xu, Robert J. Smith, Ashwin Agarwal
Publikováno v:
JAAD Case Reports
Hydralazine is a commonly prescribed antihypertensive medication that has been associated with both drug-induced lupus erythematosus and vasculitis.1 There is significant clinical, histopathologic, and serologic overlap between these entities. We pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76ca04ec7ea1b1fd99236032019c17b
https://doi.org/10.1016/j.jdcr.2019.08.020
https://doi.org/10.1016/j.jdcr.2019.08.020
Autor:
George Frimpong Boafo, Zhongjian Chen, Marwa Ahmed Sallam, Qingqing Xiao, Makhloufi Zoulikha, Wei He
Publikováno v:
Acta Pharmaceutica Sinica. B
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of several unmet medical needs, including acute lung injury/acute respiratory distress syndrome (ALI/ARDS) wherein siRNA may be implemented to modify the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9513250ae8817b12d84c4264ed5c97
https://pubmed.ncbi.nlm.nih.gov/34401226
https://pubmed.ncbi.nlm.nih.gov/34401226
Publikováno v:
Seminars in Cell & Developmental Biology
Highlights • Proteomic studies have uncovered more than a thousand cellular proteins that are present in the particles of RNA viruses. • Strikingly, nearly four hundred of these are RNA-binding proteins (RBPs). • Several virion-incorporated RBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b748a650533877810ec71ad896704db4
https://pubmed.ncbi.nlm.nih.gov/32921578
https://pubmed.ncbi.nlm.nih.gov/32921578
Autor:
Enoch, Aninagyei, Comfort Dede, Tetteh, Martin, Oppong, Alex, Boye, Desmond Omane, Acheampong
Publikováno v:
Parasite Epidemiology and Control
Introduction Artemether-Lumefantrine (A-L) remains the drug of choice for the treatment of uncomplicated malaria in Ghana. However, the pharmaco-activity of A-L has not been assessed on various Plasmodium falciparum Kelch 13 and Pfmdr1 genes. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fa85b06cdb2f627dd7f876606012203
https://pubmed.ncbi.nlm.nih.gov/33163636
https://pubmed.ncbi.nlm.nih.gov/33163636
Autor:
Nabiya Shahroz, Amber Kiyani
Publikováno v:
JAAD Case Reports
JAAD Case Reports, Vol 4, Iss 2, Pp 135-137 (2018)
JAAD Case Reports, Vol 4, Iss 2, Pp 135-137 (2018)
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can involve oral mucosal membranes in up to 45% of patients.1 Oral presentation is commonly described as erythema involving multiple oral sites. Oral ulceration is relatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ce4dc461fc6506df21eede70daf41a
https://doi.org/10.1016/j.jdcr.2017.08.008
https://doi.org/10.1016/j.jdcr.2017.08.008
Publikováno v:
Chemical Engineering Journal
Graphical abstract
Highlights • Virus-induced infections like SARS-CoV-2 is a serious threat to human health and economics. • SARS-CoV-2 sheds out through stools making a possible faecal-oral route of transmission to environment matrix. •
Highlights • Virus-induced infections like SARS-CoV-2 is a serious threat to human health and economics. • SARS-CoV-2 sheds out through stools making a possible faecal-oral route of transmission to environment matrix. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e55aba1f8a063196b59cfc23c19f8b
https://doi.org/10.1016/j.cej.2020.126893
https://doi.org/10.1016/j.cej.2020.126893