Zobrazeno 1 - 10
of 152
pro vyhledávání: '"drug-membrane interactions"'
Publikováno v:
Reviews in Analytical Chemistry, Vol 37, Iss 1, Pp 233-243 (2017)
A better elucidation of molecular mechanisms underlying drug-membrane interaction is of great importance for drug research and development. To date, different biochemical and biophysical methods have been developed to study biological membranes at mo
Externí odkaz:
https://doaj.org/article/5add4bcddf4f4ab18c5bfb520d9ff545
Autor:
Alessandra Luchini, Giuseppe Vitiello
Publikováno v:
Biomimetics, Vol 6, Iss 1, p 3 (2020)
Cell membranes are very complex biological systems including a large variety of lipids and proteins. Therefore, they are difficult to extract and directly investigate with biophysical methods. For many decades, the characterization of simpler biomime
Externí odkaz:
https://doaj.org/article/5b677652a14e410690077314e2b756ac
Akademický článek
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Publikováno v:
Molecules, Vol 20, Iss 3, Pp 3868-3897 (2015)
The angiotensin II (Ang II) type 1 and type 2 receptors (AT1R and AT2R) orchestrate an array of biological processes that regulate human health. Aberrant function of these receptors triggers pathophysiological responses that can ultimately lead to de
Externí odkaz:
https://doaj.org/article/b5cd7bb718df4d09a1e927db22b0bf86
Akademický článek
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Autor:
Klaudia Kwiecińska, Anna Stachowicz-Kuśnierz, Beata Korchowiec, Maciej Roman, Wojciech M. Kwiatek, Anna Jagusiak, Irena Roterman, Jacek Korchowiec
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8935
The uptake and distribution of doxorubicin in the MCF7 line of breast-cancer cells were monitored by Raman measurements. It was demonstrated that bioavailability of doxorubicin can be significantly enhanced by applying Congo red. To understand the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2635802e8d532860c0a1c3c9e5e5dba
https://doi.org/10.3390/ijms23168935
https://doi.org/10.3390/ijms23168935
Autor:
Conrad, Michael J., Singer, S. J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1979 Oct 01. 76(10), 5202-5206.
Externí odkaz:
https://www.jstor.org/stable/70416
Molecular transport mechanisms of poorly soluble hydrophobic drug compounds to lipid membranes were investigated using molecular dynamics (MD) simulations. The model compound danazol was used to investigate the mechanism(s) by which bile micelles del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f97df2009cb45ce21387439cfe4fb32
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-431581
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-431581
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8745, p 8745 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 8745, p 8745 (2020)
Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are amongst the most prescribed medications worldwide. Most statins work as a competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGR), but sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbee61fb05d2b8f097a6ff88e61d0ab
http://europepmc.org/articles/PMC7699354
http://europepmc.org/articles/PMC7699354
Akademický článek
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