Výsledky vyhledávání - "drug therapy breast neoplasms"

Untersuchung des prognostischen und prädiktiven Aussagewertes der GPER 1-Expression in Mammakarzinompatientinnen mit endokriner Therapie

Autor: Plätzer, Eva

Das Mammakarzinom ist mit jährlich 1,4 Millionen Neuerkrankungen weltweit die häufigste maligne Tumorerkrankung und ebenso mit jährlich 460.000 Todesfällen weltweit die häufigste durch ein Malignom bedingte Todesursache der Frau (Jemal et al., 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1224c80690dd2d0c1e3de6670ef481f2
https://epub.uni-regensburg.de/53163/

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Impact of baseline and on-treatment glycemia on everolimus-exemestane efficacy in patients with hormone receptor-positive advanced breast cancer (EVERMET)

Autor: Giovanna Catania, Fabio Puglisi, Dario Trapani, Federico Nichetti, Lorenzo Gerratana, Alessandra Fabi, Marika Cinausero, Michela Palleschi, Agnese Losurdo, Filippo Montemurro, Enrico Cortesi, Rebecca Pedersini, Andrea Rocca, Carlo Alberto Giorgi, Grazia Arpino, Gaia Griguolo, Lorenzo Castagnoli, Giancarlo Pruneri, Andrea Michelotti, Giuseppe Curigliano, Valentina Guarneri, Francesca Ligorio, Giovanni Randon, Daniele Generali, Emanuela Ferraro, Luca Moscetti, A. Fabbri, Arta Ajazi, Elisa Agostinetto, Claudia De Angelis, Amelia Vantaggiato, Carmen G. Rea, Antonio Marra, Filippo de Braud, Nicla La Verde, Debora Basile, Lucia Del Mastro, Luigi Mariani, Salvatore Lo Vullo, Mariangela Ciccarese, Anna Moretti, Simone Scagnoli, Claudio Vernieri, Ottavia Bernocchi, Chiara Molinelli, Andrea Milani, Luca Lalli

Purpose: The mTOR complex C1 (mTORC1) inhibitor everolimus in combination with the aromatase inhibitor exemestane is an effective treatment for patients with hormone receptor—positive (HR+), HER2-negative (HER2−), advanced breast cancer (HR+/HER2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c55553685783be74ffe3ea6e753cdb9
https://hdl.handle.net/11573/1676736

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Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts

Autor: Nandini, Asokan, Stephan, Daetwyler, Stefanie N, Bernas, Christopher, Schmied, Steffen, Vogler, Katrin, Lambert, Manja, Wobus, Martin, Wermke, Gerd, Kempermann, Jan, Huisken, Michael, Brand, Martin, Bornhäuser

Publikováno v: Scientific reports 10(1), 13254 (2020). doi:10.1038/s41598-020-69956-2
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports

Understanding mechanisms mediating tumor metastasis is crucial for diagnostic and therapeutic targeting. Here, we take advantage of a transparent embryonic zebrafish xenograft model (eZXM) to visualize and track metastatic cells in real time using se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fd93745af817e473f18ff75ac56332b3

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Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells

Autor: Silvana K. Haßel, Seyed Mohammad Taghdisi, Anna Jonczyk, H. James Stunden, Günter Mayer, Joachim L. Schultze, Marc Beyer, Laia Civit, Eicke Latz, Michael Blank, Carsten Gröber

Publikováno v: Civit Pitarch, L, Taghdisi, S M, Jonczyk, A, Hassel, S K, Gröber, C, Blank, M, Stunden, J, Beyer, M, Schultze, J, Latz, E & Mayer, G 2018, ' Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells ', Biochimie, vol. 145, pp. 53-62 . https://doi.org/10.1016/j.biochi.2017.10.007
Biochimie 145, 53-62 (2018). doi:10.1016/j.biochi.2017.10.007

The sensitive and specific detection of pathogenic cells is essential in clinical diagnostics. To achieve this, molecular tools are required that unequivocally recognise appropriate cell surface molecules, such as biomarkers that come along with dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c5b5cc0c510193c317291b71c3107a
https://doi.org/10.1016/j.biochi.2017.10.007

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Prevalence of Cerebral Small-Vessel Disease in Long-Term Breast Cancer Survivors Exposed to Both Adjuvant Radiotherapy and Chemotherapy

Autor: Sanne B. Schagen, Monique M.B. Breteler, Meike W. Vernooij, Willem Boogerd, Caroline Seynaeve, Vincent Koppelmans, M. Arfan Ikram

Publikováno v: Journal of clinical oncology 33(6), 588-593 (2015). doi:10.1200/JCO.2014.56.8345
Journal of Clinical Oncology, 33(6), 588-593. American Society of Clinical Oncology

Purpose Adjuvant radiotherapy and chemotherapy for breast cancer have been related to transient ischemic attacks and stroke. To date, no studies have investigated the relationship between these adjuvant therapies and subclinical cerebral small-vessel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e7c0a1691f177a54ebbc72c052347c
https://hdl.handle.net/1765/86077

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Late effects of adjuvant chemotherapy for breast cancer on fine motor function

Autor: Hoogendam, Yoo Young, Schagen, Sanne B, Ikram, M Arfan, Boogerd, Willem, Seynaeve, Caroline, Seidler, Rachael D, Breteler, Monique M B, Van der Geest, Jos N, Koppelmans, Vincent

Publikováno v: Psycho-oncology 24(12), 1799-1807 (2015). doi:10.1002/pon.3796

Adjuvant chemotherapy for breast cancer has been associated with deterioration of fine motor skill. Which aspects of motor performance are underlying this problem is unclear but important because manual motor deterioration could affect quality of lif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6abd67ec7f5143a7b48f8ebfb03bdede
https://pubmed.ncbi.nlm.nih.gov/25756497

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Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy

Autor: Koppelmans, Vincent, de Groot, Marius, de Ruiter, MB (Michiel), Boogerd, W, Seynaeve, Caroline, Vernooij, Meike, Niessen, Wiro, Schagen, SB, Breteler, Monique

Publikováno v: Human brain mapping, 35(3), 889-899. Wiley-Liss Inc.
Hum Brain Mapp
Human brain mapping 35(3), 889-899 (2012). doi:10.1002/hbm.22221
Human Brain Mapping, 35(3), 889-899. Wiley-Liss Inc.

OBJECTIVES: To date, only four small studies have investigated the effects of adjuvant chemotherapy for breast cancer on the microstructure of cerebral white matter with magnetic resonance imaging (MRI). These studies, which were conducted shortly up

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::73d911438ccf35125cf6f1732c938e0f
https://pure.amc.nl/en/publications/global-and-focal-white-matter-integrity-in-breast-cancer-survivors-20-years-after-adjuvant-chemotherapy(a14f12f5-43e2-4cee-a700-15bc7c6636f8).html

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Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy

Autor: Sanne B. Schagen, Willem Boogerd, Monique M.B. Breteler, Caroline Seynaeve, Chad M. Gundy, Vincent Koppelmans

Publikováno v: Journal of Clinical Oncology, 30(10), 1080-1086. American Society of Clinical Oncology
Journal of clinical oncology 30(10), 1080-1086 (2012). doi:10.1200/JCO.2011.37.0189

Purpose Adjuvant chemotherapy for breast cancer can have adverse effects on cognition shortly after administration. Whether chemotherapy has any long-term effects on cognition is largely unknown, yet it becomes increasingly relevant because of the wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163df80ff540a9b49f811066324f4c64
https://pubmed.ncbi.nlm.nih.gov/22370315

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Global and focal brain volume in long-term breast cancer survivors exposed to adjuvant chemotherapy

Autor: Henri A. Vrooman, Willem Boogerd, Wiro J. Niessen, Sanne B. Schagen, Caroline Seynaeve, Vincent Koppelmans, Fedde van der Lijn, Aad van der Lugt, Monique M.B. Breteler, Michiel B. de Ruiter

Publikováno v: Breast cancer research and treatment, 132(3)2012
Breast Cancer Research and Treatment, 132(3), 1099-1106. Springer New York
Breast cancer research and treatment, 132(3), 1099-1106. Springer New York
Breast cancer research and treatment 132(3), 1099-1106 (2011). doi:10.1007/s10549-011-1888-1

A limited number of studies have associated adjuvant chemotherapy with structural brain changes. These studies had small sample sizes and were conducted shortly after cessation of chemotherapy. Results of these studies indicate local gray matter volu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16bf1be88b3d56e4ff2c94eff30ef81
http://resolver.tudelft.nl/uuid:035a1f2c-191f-4f1f-8a60-6be3ece14a7a

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