Zobrazeno 1 - 10 of 77 pro vyhledávání: '"drug therapy [Depression]"'
1
Pharmacologic treatment of depression in Alzheimer's disease
Autor: Robert Haussmann, Markus Donix
Publikováno v: International clinical psychopharmacology 38(2), 81-88 (2023). doi:10.1097/YIC.0000000000000439
Major depressive disorder and Alzheimer's disease are common among older people, frequently co-occur and severely impact the quality of life. Unfortunately, data on the efficacy of pharmacologic treatment of depressive symptoms in patients with the n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885523d6f1eb6a5f195e56899a010d2c
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2
Effect of intravenous alteplase on post-stroke depression in the WAKE UP trial
Autor: Bastian Cheng, Salvador Pedraza, Keith W. Muir, Florent Boutitie, Matthias Endres, Alina Königsberg, Robin Lemmens, Sönke Arlt, Susanne Sehner, Christian Gerloff, Jochen B. Fiebach, Claus Z Simonsen, Vincent Thijs, Götz Thomalla, Martin Ebinger, Norbert Nighoghossian, Joaquín Serena
Publikováno v: European Journal of Neurology
European Journal of Neurology, 2021, 28 (6), pp.2017-2025. ⟨10.1111/ene.14797⟩
Königsberg, A, Sehner, S, Arlt, S, Cheng, B, Simonsen, C Z, Boutitie, F, Serena, J, Thijs, V, Ebinger, M, Endres, M, Fiebach, J B, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Gerloff, C, Thomalla, G & the WAKE-UP investigators 2021, ' Effect of intravenous alteplase on post-stroke depression in the WAKE UP trial ', European Journal of Neurology, vol. 28, no. 6, pp. 2017-2025 . https://doi.org/10.1111/ene.14797
European journal of neurology 28(6), 2017-2025 (2021). doi:10.1111/ene.14797
European Journal of Neurology, Wiley, 2021, 28 (6), pp.2017-2025. ⟨10.1111/ene.14797⟩
European Journal of Neurology, 2021, vol.28, núm. 6, p. 2017-2025
Articles publicats (IdIBGi)
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BACKGROUND AND PURPOSE: The aim was to study the effect of intravenous alteplase on the development of post-stroke depression (PSD) in acute stroke patients, and to identify predictors of PSD. METHODS: This post hoc analysis included patients with un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7175d5cb664126fdddb309ae82c150
https://lirias.kuleuven.be/handle/20.500.12942/686728
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3
A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression
Autor: Jan Krumsiek, Helena U. Zacharias, Henry Völzke, Seryan Atasoy, Gabi Kastenmüller, Nele Friedrich, Maik Pietzner, Karl-Heinz Ladwig, Christian Gieger, Johannes Hertel, Sonja Kunze, Karoline Lukaschek, Hamimatunnisa Johar, Hans J. Grabe, Matthias Nauck
Publikováno v: Mol. Psychiatry 26, 7372–7383 (2021)
Molecular psychiatry 26(12), 7372-7383 (2021). doi:10.1038/s41380-021-01176-0
Depression constitutes a leading cause of disability worldwide. Despite extensive research on its interaction with psychobiological factors, associated pathways are far from being elucidated. Metabolomics, assessing the final products of complex bioc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533ea050bbb27d9f64881dbda9cd715d
https://pubmed.ncbi.nlm.nih.gov/34088979
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4
To Be Continued? Long-Term Treatment Effects of Antidepressant Drug Classes and Individual Antidepressants on the Risk of Developing Dementia: A German Case-Control Study
Autor: Claudia Bartels, Karel Kostev, Michael Belz, Jens Bohlken, Jens Wiltfang, Philipp Hessmann, Jonathan Vogelgsang
Publikováno v: The journal of clinical psychiatry 81(5), 19m13205 (2020). doi:10.4088/JCP.19m13205
Background Given the need for disease-modifying therapies for dementia, drug repurposing appears to be a promising approach, at least as a risk reduction treatment. Preclinical studies suggest that antidepressants-in particular selective serotonin re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69ae8d96a6d95f3c5c018ed5f5eab51
https://pub.dzne.de/record/164432
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5
Potentially inappropriate medication: Association between the use of antidepressant drugs and the subsequent risk for dementia
Autor: Michael Pentzek, Birgitt Wiese, Wolfgang Maier, Edelgard Mösch, Anke Oey, Kathrin Heser, Siegfried Weyerer, Michael Wagner, Tobias Luck, Jochen Werle, Steffi G. Riedel-Heller, Susanne Röhr, Angela Fuchs, Christian Brettschneider, Martin Scherer, Hendrik van den Bussche, Hanna Kaduszkiewicz, Hans-Helmut König, Horst Bickel
Publikováno v: Journal of affective disorders 226, 28-35 (2018). doi:10.1016/j.jad.2017.09.016
Background Potentially inappropriate medication (PIM) is associated with an increased risk for detrimental health outcomes in elderly patients. Some antidepressant drugs are considered as PIM, but previous research on the association between antidepr
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6
Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer's Dementia in Individuals With Previous Depression
Autor: Bartels, Claudia, Wagner, Michael, Wolfsgruber, Steffen, Ehrenreich, Hannelore, Schneider, Anja, Initiative, Alzheimer’s Disease Neuroimaging
Publikováno v: The American journal of psychiatry 175(3), 232-241 (2018). doi:10.1176/appi.ajp.2017.17040404
Depression is associated with an increased risk of Alzheimer's disease. Research has shown that the selective serotonin reuptake inhibitor (SSRI) citalopram decreases amyloid-β generation and plaque load. The authors evaluated the impact of SSRI tre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0ab92605ec2f29136d16f85986f421
https://pubmed.ncbi.nlm.nih.gov/30302688
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7
The Impact of Depressive Symptoms on Healthcare Costs in Late Life: Longitudinal Findings From the AgeMooDe Study
Autor: Jens-Oliver Bock, Birgitt Wiese, Michael Wagner, Siegfried Weyerer, Wolfgang Maier, Hanna Kaduszkiewicz, Hans-Helmut König, Anne Stark, André Hajek, Janine Stein, Steffi G. Riedel-Heller, Jochen Werle, Lilia Moor
Publikováno v: American journal of geriatric psychiatry 25(2), 131-141 (2017). doi:10.1016/j.jagp.2016.10.011
Objective To examine whether depressive symptoms affect healthcare costs in old age longitudinally. Design Multicenter prospective observational cohort study (two waves with n t1 = 1,195 and n t2 = 951) in Germany. Setting Community. Participants Par
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a11a68155ee1a7030f85014e5b6629
https://pub.dzne.de/record/139132
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8
Depressive symptoms and depression in people screened positive for dementia in primary care - results of the DelpHi-study
Autor: Tilly Eichler, Diana Wucherer, Adina Dreier, Wolfgang Hoffmann, Bernhard Michalowsky, Melanie Reimann, Jochen René Thyrian
Publikováno v: International psychogeriatrics 28(6), 929-937 (2016). doi:10.1017/S1041610215002458
Background:Dementia and depression are common syndromes in the elderly. There is lack of knowledge concerning the frequency of depressive symptoms in people with dementia (PWD) and factors associated with depression. The aim of this analysis is to (a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888b9064f133eb16c76724a869b4bcf1
https://pubmed.ncbi.nlm.nih.gov/26785854
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9
[Treating Late Life Depression with Antidepressants--A Summary of Recommendations in International Guidelines]
Autor: Heilmann, K. E., Wagner, M., Riedel-Heller, S., Maier, W., Jessen, F.
Publikováno v: Fortschritte der Neurologie, Psychiatrie 83(07), 381-391 (2015). doi:10.1055/s-0035-1553315
Late life depression is associated with severe health consequences, e.g. elevated risk of medical comorbidity and decreased quality of life. This paper summarizes the recommendations of the international guidelines on evidence-based pharmacological t
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https://pubmed.ncbi.nlm.nih.gov/26200043
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10
Long-term treatment with L-DOPA or pramipexole affects adult neurogenesis and corresponding non-motor behavior in a mouse model of Parkinson's disease
Autor: Wei-Hua Chiu, Lukas Maurer, Wolfgang H. Oertel, Candan Depboylu, Vincent Ries, Guido Hermanns, Günter U. Höglinger, Andrea Windolph
Publikováno v: Neuropharmacology 95, 367-376 (2015). doi:10.1016/j.neuropharm.2015.03.020
Non-motor symptoms such as hyposmia and depression are often observed in Parkinson's disease (PD) and can precede the onset of motor symptoms for years. The underlying pathological alterations in the brain are not fully understood so far. Dysregulati
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