Zobrazeno 1 - 10 of 17 pro vyhledávání: '"drug therapy [Brain Ischemia]"'
1
Sex differences in imaging and clinical characteristics of patients from the WAKE--UP trial
Autor: Anke Wouters, Lauranne Scheldeman, Hannelore Liessens, Patrick Dupont, Florent Boutitie, Bastian Cheng, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Christian Gerloff, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Vincent Thijs, Götz Thomalla, Robin Lemmens
Publikováno v: European Journal of Neurology
European Journal of Neurology, 2022, 30 (3), pp.641-647. ⟨10.1111/ene.15629⟩
European journal of neurology 30(3), 641-647 (2022). doi:10.1111/ene.15629
Wouters, A, Scheldeman, L, Liessens, H, Dupont, P, Boutitie, F, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G & Lemmens, R 2023, ' Sex differences in imaging and clinical characteristics of patients from the WAKE-UP trial ', European Journal of Neurology, vol. 30, no. 3, pp. 641-647 . https://doi.org/10.1111/ene.15629
BACKGROUND AND PURPOSE: Sex-based differences in acute ischemic stroke are a well-known phenomenon. We aimed to explore these differences between women and men in the Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke (WAKE-UP) trial. ME
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6fd44d43fd4280ca4fc48780b5dd0c
https://lirias.kuleuven.be/handle/20.500.12942/706971
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2
Estimating nocturnal stroke onset times by magnetic resonance imaging in the WAKE-UP trial
Autor: Salvador Pedraza, Christian Gerloff, Jochen B. Fiebach, Robin Lemmens, Eckhard Schlemm, Keith W. Muir, Alina Königsberg, Josep Puig, Matthias Endres, Martin Ebinger, Hans O. Pinnschmidt, Florent Boutitie, Claus Z Simonsen, Vincent Thijs, Götz Thomalla, Jens Fiehler, Anke Wouters, Bastian Cheng, Ivana Galinovic
Publikováno v: International journal of stroke 17(3), 323-330 (2022). doi:10.1177/17474930211059608
Cheng, B, Pinnschmidt, H, Königsberg, A, Schlemm, E, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C & Thomalla, G 2022, ' Estimating nocturnal stroke onset times by magnetic resonance imaging in the WAKE-UP trial ', International Journal of Stroke, vol. 17, no. 3, pp. 323-330 . https://doi.org/10.1177/17474930211059608
Background Fluid-attenuated inversion recovery (FLAIR) sequences have gained a role to guide treatment of patients with unknown time of stroke symptom onset. Evolution of signal intensities in FLAIR is associated with time since stroke onset with con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6201f19bd03b378a9d333f772c64f3
https://doi.org/10.1177/17474930211059608
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3
Benefit of Intravenous Thrombolysis in Acute Ischemic Stroke Patients With High Cerebral Microbleed Burden
Autor: David J. Werring, Christian H. Nolte, Matthias Endres, Ludwig Schlemm
Publikováno v: Stroke 51(1), 232-239 (2020). doi:10.1161/STROKEAHA.119.027633
Background and Purpose— Cerebral microbleeds (CMBs) are a risk factor for intracranial hemorrhage. Whether intravenous thrombolysis (IVT) improves functional outcome in acute ischemic stroke patients with CMBs is unknown. We aimed to estimate the t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568ef24458db751aa61bf054ed8a04fe
https://doi.org/10.1161/strokeaha.119.027633
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5
Early effect of thrombolysis on structural brain network organisation after anterior-circulation stroke in the randomized WAKE-UP trial
Autor: Eckhard Schlemm, Märit Jensen, Amy Kuceyeski, Keith Jamison, Thies Ingwersen, Carola Mayer, Alina Königsberg, Florent Boutitie, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ivana Galinovic, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Josep Puig, Claus Z. Simonsen, Vincent Thijs, Anke Wouters, Christian Gerloff, Götz Thomalla, Bastian Cheng
Publikováno v: Human brain mapping 43(16), 5053-5065 (2022). doi:10.1002/hbm.26073
Schlemm, E, Jensen, M, Kuceyeski, A, Jamison, K, Ingwersen, T, Mayer, C, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2022, ' Early effect of thrombolysis on structural brain network organisation after anterior-circulation stroke in the randomized WAKE-UP trial ', Human Brain Mapping, vol. 43, no. 16, pp. 5053-5065 . https://doi.org/10.1002/hbm.26073
Human Brain Mapping
Human Brain Mapping, 2022, 43 (16), pp.5053--5065. ⟨10.1002/hbm.26073⟩
The symptoms of acute ischemic stroke can be attributed to disruption of the brain network architecture. Systemic thrombolysis is an effective treatment that preserves structural connectivity in the first days after the event. Its effect on the evolu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a481fa01f882bed7d933d8a490d890
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6
Effect of intravenous alteplase on post-stroke depression in the WAKE UP trial
Autor: Bastian Cheng, Salvador Pedraza, Keith W. Muir, Florent Boutitie, Matthias Endres, Alina Königsberg, Robin Lemmens, Sönke Arlt, Susanne Sehner, Christian Gerloff, Jochen B. Fiebach, Claus Z Simonsen, Vincent Thijs, Götz Thomalla, Martin Ebinger, Norbert Nighoghossian, Joaquín Serena
Publikováno v: European Journal of Neurology
European Journal of Neurology, 2021, 28 (6), pp.2017-2025. ⟨10.1111/ene.14797⟩
Königsberg, A, Sehner, S, Arlt, S, Cheng, B, Simonsen, C Z, Boutitie, F, Serena, J, Thijs, V, Ebinger, M, Endres, M, Fiebach, J B, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Gerloff, C, Thomalla, G & the WAKE-UP investigators 2021, ' Effect of intravenous alteplase on post-stroke depression in the WAKE UP trial ', European Journal of Neurology, vol. 28, no. 6, pp. 2017-2025 . https://doi.org/10.1111/ene.14797
European journal of neurology 28(6), 2017-2025 (2021). doi:10.1111/ene.14797
European Journal of Neurology, Wiley, 2021, 28 (6), pp.2017-2025. ⟨10.1111/ene.14797⟩
European Journal of Neurology, 2021, vol.28, núm. 6, p. 2017-2025
Articles publicats (IdIBGi)
DUGiDocs – Universitat de Girona
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BACKGROUND AND PURPOSE: The aim was to study the effect of intravenous alteplase on the development of post-stroke depression (PSD) in acute stroke patients, and to identify predictors of PSD. METHODS: This post hoc analysis included patients with un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7175d5cb664126fdddb309ae82c150
https://lirias.kuleuven.be/handle/20.500.12942/686728
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7
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies
Autor: Adam Denes, Nicolai Franzmeier, Steffanie Heindl, Olga Carofiglio, Thomas Arzberger, Peter T. Nelson, Nikolett Lénárt, Alessio Ricci, Tibor Hortobágyi, Arthur Liesz, Dieter Edbauer, Qihui Zhou, Ann M. Stowe
Publikováno v: Journal of Experimental Medicine
Journal of experimental medicine 218(8), e20202411 (2021). doi:10.1084/jem.20202411
The Journal of Experimental Medicine
Heindl et al. describe the local proliferation and clustering of T cells in the brain of mice and humans after stroke. This previously unrecognized phenomenon could explain why blocking cerebral leukocyte invasion might fail to improve long-term stro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85b3077423c61350254debe6602a6ad
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8
Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke
Autor: Keith W. Muir, Martin Ebinger, Christian Gerloff, Thies Ingwersen, Salvador Pedraza, Alina Königsberg, Claus Z Simonsen, Götz Thomalla, Josep Puig, Eckhard Schlemm, Jochen B. Fiebach, Jens Fiehler, Anke Wouters, Bastian Cheng, Vincent Thijs, Ivana Galinovic, Matthias Endres, Florent Boutitie, Robin Lemmens, Norbert Nighoghossian
Publikováno v: Nature Communications 12(1), 2590 (2021). doi:10.1038/s41467-021-22786-w
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schlemm, E, Ingwersen, T, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2021, ' Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke ', Nature Communications, vol. 12, no. 1, 2590 . https://doi.org/10.1038/s41467-021-22786-w
Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke aims to restore compromised blood flow and prevent further neuronal damage. Despite the proven clinical efficacy of this treatment, little is known about the short-te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4157e758454a7f30cb973ccad7559ebd
https://pubmed.ncbi.nlm.nih.gov/33972513
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9
Different Mismatch Concepts for Magnetic Resonance Imaging–Guided Thrombolysis in Unknown Onset Stroke
Autor: Matthias Endres, Jochen B. Fiebach, Anke Wouters, Bastian Cheng, Soren Christensen, Robin Lemmens, Christian Gerloff, Patrick Dupont, Keith W. Muir, Martin Ebinger, Salvador Pedraza, Florent Boutitie, Claus Z Simonsen, Götz Thomalla, Norbert Nighoghossian, Vincent Thijs, Lauranne Scheldeman
Publikováno v: Annals of neurology 87(6), 931-938 (2020). doi:10.1002/ana.25730
Annals of Neurology
Annals of Neurology, 2020, 87 (6), pp.931--938. ⟨10.1002/ana.25730⟩
Scheldeman, L, Wouters, A, Boutitie, F, Dupont, P, Christensen, S, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G, Lemmens, R & for the WAKE-UP Investigators 2020, ' Different Mismatch Concepts for Magnetic Resonance Imaging–Guided Thrombolysis in Unknown Onset Stroke ', Annals of Neurology, vol. 87, no. 6, pp. 931-938 . https://doi.org/10.1002/ana.25730
OBJECTIVE: To explore the prevalence of the perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch and response to intravenous thrombolysis in the WAKE-UP trial. METHODS: We performed a prespecified post hoc analysis of ischemic s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d4581416dbc2ffa3e11a3debdb2959
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