Výsledky vyhledávání - "drug therapy/virology"

Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc

Autor: Davey M. Smith, Susan J. Little, Douglas D. Richman, Sara Gianella, Josué Pérez-Santiago, Antoine Chaillon, Parris Jordan, Joel O. Wertheim, Caroline Ignacio, Steven M. Lada, Maile Y. Karris, Sanjay Mehta

Publikováno v: Journal of virology, vol 92, iss 3
Chaillon, Antoine; Gianella, Sara; Lada, Steven M; Perez-Santiago, Josué; Jordan, Parris; Ignacio, Caroline; et al.(2018). Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.. Journal of virology, 92(3). doi: 10.1128/JVI.01589-17. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/2dz5q4q8

Residual viremia is common during antiretroviral therapy (ART) and could be caused by ongoing low-level virus replication or by release of viral particles from infected cells. ART intensification should impact ongoing viral propagation but not virion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5db9c6ca94addc5ddb77c1d14d6fc0
https://escholarship.org/uc/item/2dz5q4q8

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Ethnicity predicts viral rebound after travel to the tropics in HIV-infected travelers to the tropics in the Swiss HIV Cohort Study

Autor: Gebreselassie, H M, Kraus, D, Fux, C A, Haubitz, S, Scherrer, A, Hatz, C, Veit, Olivia, Stoeckle, M, Fehr, J, De Lucia, Sylvain, Cavassini, M, Bernasconi, Enos, Schmid, Patrick, Furrer, H, Staehelin, C, Calmy, Alexandra

Publikováno v: HIV Medicine, Vol. 18, No 8 (2017) pp. 564-572

Objectives The number of HIV-infected individuals from developed countries travelling to tropical and subtropical areas has increased as a result of the clinical and survival benefits of combination antiretroviral therapy. The aim of our study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b52fe59d5a086c6be92cc894ae6f9f
https://doi.org/10.1111/hiv.12491

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Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient

Autor: Marie-Christine Venable, Federica Giannotti, Julie Carbonneau, Guy Boivin, Ana Rita Gonçalves, Clément Fage, Liva Checkmahomed, Manuel Schibler, Laurent Kaiser, Yacine Abed

Publikováno v: Antiviral Therapy, Vol. 24, No 8 (2019) pp. 581-587

Background Neuraminidase (NA) inhibitors (NAIs), including oseltamivir and zanamivir, play an important therapeutic role against influenza infections in immunocompromised patients. In such settings, however, NAI therapy may lead to the emergence of r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a2f6cf395933198196bcfff96dd907
https://archive-ouverte.unige.ch/unige:147186

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Autor: Frank Jühling, Yujin Hoshida, Atsushi Ono, Thomas F. Baumert

Publikováno v: BMC Medicine
BMC Medicine, BioMed Central, 2017, 15 (1), ⟨10.1186/s12916-017-0815-7⟩
BMC Medicine, 2017, 15 (1), ⟨10.1186/s12916-017-0815-7⟩

PMC5348895; Hepatitis C virus infection is a major cause of hepatocellular carcinoma worldwide. Interferon has been the major antiviral treatment, yielding viral clearance in approximately half of patients. New direct-acting antivirals substantially

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a92f14a1255d75d491b41a7c7c744b1
http://europepmc.org/articles/PMC5348895

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HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection

Autor: Christophe Vanpouille, Andrea Lisco, Sara Gianella, Sanjay Mehta, Antoine Chaillon, Davey M. Smith, M. Vargas, Gemma Caballero, Parris Jordan

Publikováno v: Chaillon, Antoine; Smith, Davey M; Vanpouille, Christophe; Lisco, Andrea; Jordan, Parris; Caballero, Gemma; et al.(2017). HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection.. Journal of acquired immune deficiency syndromes (1999), 74(1), 95-102. doi: 10.1097/QAI.0000000000001156. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/59g5j63f
Journal of acquired immune deficiency syndromes (1999), vol 74, iss 1

Author(s): Chaillon, Antoine; Smith, Davey M; Vanpouille, Christophe; Lisco, Andrea; Jordan, Parris; Caballero, Gemma; Vargas, Milenka; Gianella, Sara; Mehta, Sanjay R | Abstract: BackgroundUnderstanding the dynamics of HIV across anatomic compartmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77560aefec1d5c35b503c23bf6a76160
http://www.escholarship.org/uc/item/59g5j63f

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Standard vaccines increase HIV-1 transcription during antiretroviral therapy

Autor: Sara Gianella, Davey M. Smith, Pedro Castro, Christina Yek, Montserrat Plana, Felipe García, Marta Massanella, Konrad Scheffler

Publikováno v: Yek, Christina; Gianella, Sara; Plana, Montserrat; Castro, Pedro; Scheffler, Konrad; García, Felipe; et al.(2016). Standard vaccines increase HIV-1 transcription during antiretroviral therapy.. AIDS (London, England), 30(15), 2289-2298. doi: 10.1097/QAD.0000000000001201. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/6gv1m2q8
AIDS (London, England), vol 30, iss 15

Author(s): Yek, Christina; Gianella, Sara; Plana, Montserrat; Castro, Pedro; Scheffler, Konrad; Garcia, Felipe; Massanella, Marta; Smith, Davey M | Abstract: ObjectivesCurative strategies using agents to perturb the HIV reservoir have demonstrated on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6db3280368f17405b8ecbb7c33b63e
http://www.escholarship.org/uc/item/6gv1m2q8

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Comparative evaluation of seven resistance interpretation algorithms and their derived genotypic inhibitory quotients for the prediction of 48 week virological response to darunavir-based salvage regimens

Autor: Andrea Calcagno, Antonio D'Avolio, Valeria Ghisetti, Giovanni Di Perri, Paola Vitiello, Lorena Baietto, Silvia Magnani, Daniel Gonzalez de Requena, Ottavia Viganò, C. Cometto, Stefano Rusconi, Massimo Galli, Stefania Ferramosca, Stefano Bonora

Publikováno v: Journal of Antimicrobial Chemotherapy. 66:192-200

BACKGROUND the darunavir genotypic inhibitory quotient (gIQ) has been suggested as one of the predictors of virological response to darunavir-containing salvage regimens. Nevertheless, which resistance algorithm should be used to optimize the calcula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03006c54111f77e07a71ee150669d7a
https://doi.org/10.1093/jac/dkq384

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Raltegravir 1200 mg once daily versus raltegravir 400 mg twice daily, with tenofovir disoproxil fumarate and emtricitabine, for previously untreated HIV-1 infection: a randomised, double-blind, parallel-group, phase 3, non-inferiority trial

Autor: Brenda Homony, Claudine Duvivier, I Neves, Christine Katlama, Gordon Crofoot, Natalia Zakharova, Stefan Esser, Hedy Teppler, Xia Xu, Randi Y. Leavitt, Adriano Lazzarin, CR Mejia, M Mustafa, Olga Aleksandrovna Tsybakova, James H McMahon, Brian Conway, Juan Carlos Rondon, Faiza Ajana, TS Chow, M Oyanguren, EM Rojas, Jean-Michel Molina, A Avihingsanon, Carlos Perez, Koldo Aguirrebengoa, Karen T. Tashima, M Wolff, Yazdan Yazdanpanah, Eugenia Negredo, R Serrao, Richard James Moore, Carmen D. Zorrilla, Winai Ratanasuwan, C Echiverri, L Panther, Joel E. Gallant, Andri Rauch, HH Lin, Bernard Vandercam, Anthony John Scarsella, L Hercilla, A. Antinori, Pedro Cahn, Albrecht Stoehr, DE Sweet, Mariette E. Botes, Johannes R. Bogner, Hans Jaeger, Soumi Gupta, Olaf Degen, Nathan Clumeck, H. Hartl, PJ Ruane, Ckc Lee, Juergen K. Rockstroh, Richard Kaplan, N Roth, MF Lasso, Rassool, Gatell Jm, Markus Bickel, Nelson, M Moutschen, V Sotnikov, R Kaplan, Amanda Clarke, WH Sheng, Anchalee Avihingsanon, Doug Ward, L Vanderkerckhove, Daniel S Berger, Sasisopin Kiertiburanakul, Ghr Smith, Sandy L. Rawlins, Mohammed Rassool, A d'Arminio Monforte, Paul E. Sax, Margaret A. Johnson, F. Maggiolo, Fernando Maltez, Ramirez, Evgeny Voronin, Eyal Shahar, S Henn, Cheryl McDonald, A Ustianowski, MT Bloch, E Arathoon, Peter Sklar, LD Gonzalez, Enrique Ortega, Louis Sloan, Amneris E. Luque, Isabelle Poizot-Martin, M. H. Losso, Giuliano Rizzardini, Debbie Hagins, Lilly East, Andrea Gori, Matthias Cavassini, Princy Kumar, Isabel Cassetti, G. Di Perri, Benedetto Maurizio Celesia, Evelyn Rojas, S Ferret, Jerry L. Cade, KM Mullane, CB Hsiao, Dane Turner, Eugénio Teófilo, Bach-Yen Nguyen, Craig A. Dietz, Anthony Rodgers, Elena Orlova-Morozova, Z. Sthoeger, Jean-Guy Baril, Hila Elinav, I Khaertynova, JG Saraiva da Cunha, Carl J. Fichtenbaum, G Faetkanheuer, Peter Ruane, HC Tsai, R Iskandar Shah Raja Azwa, Lerato Mohapi, Firaya Nagimova, Keikawus Arastéh, J. Durant, JD Velez, Jacques Reynes, ST Lewis, Saag, Otto Sussmann, P. Cahn, D Changpradub, Mark Bloch, RM Novak, W Ratanasuwan, Kathleen Squires, Fiona Smaill, Larissa Wenning, Jose R. Arribas, Edwin DeJesus, Don Smith, JO Morales, A. Yakovlev, Sharon Walmsley, Carolina Eugenia Chahin, I Levy, Alexandra Calmy, David James Prelutsky, David M. Asmuth, Linos Vandekerckhove, J Troya, Antonio Antela, Alan Winston, Lizette Santiago, Juan Berenguer, Marcel Stoeckle, RA Castillo, Anita Rachlis

Publikováno v: Lancet HIV
Lancet HIV, Elsevier, 2017, 4 (11), pp.e486-e494. ⟨10.1016/S2352-3018(17)30128-5⟩
LANCET HIV
The Lancet HIV, Vol. 4, No 11 (2017) pp. e486-e494

Summary Background Once daily regimens are preferred for HIV-1 treatment, to facilitate adherence and improve quality of life. We compared a new once daily formulation of raltegravir to the currently marketed twice daily formulation. Methods In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b080de940b6244d90b7b170ca487b8b0
https://hal.archives-ouvertes.fr/hal-01745628

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Cellular Viral Rebound after Cessation of Potent Antiretroviral Therapy Predicted by Levels of Multiply Spliced HIV-1 RNA Encoding nef

Autor: Marek Fischer, Beda Joos, Gabriela Bleiber, Huldrych F. Günthard, Rainer Weber, Bernard Hirschel

Publikováno v: The Journal of Infectious Diseases, Vol. 190, No 11 (2004) pp. 1979-1988
Journal of Infectious Diseases, vol. 190, no. 11, pp. 1979-1988

To characterize newly arising replication of human immunodeficiency virus (HIV) type 1 in vivo at the cellular level, distinct viral RNA species in peripheral blood mononuclear cells (PBMCs) from HIV-1-infected patients were monitored during 2 weeks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8795abb5cd62992526c1b008f7d9186
http://doc.rero.ch/record/293571/files/190-11-1979.pdf

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Can research at the end of life be a useful tool to advance HIV cure?

Autor: David J. Moore, Ronald J. Ellis, Susan J. Little, Davey M. Smith, Andy Kaytes, Jeffrey R. Taylor, Cristian L. Achim, Sara Gianella, Timothy R. Brown

Publikováno v: Gianella, S; Taylor, J; Brown, TR; Kaytes, A; Achim, CL; Moore, DJ; et al.(2017). Can research at the end of life be a useful tool to advance HIV cure?. AIDS, 31(1), 1-4. doi: 10.1097/QAD.0000000000001300. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7sq88797
AIDS (London, England), vol 31, iss 1

OPINION Can research at the end of life be a useful tool to advance HIV cure? Sara Gianella a , Jeff Taylor b , Timothy R. Brown c , Andy Kaytes b , Cristian L. Achim a , David J. Moore a , Susan J. Little a , Ronald J. Ellis a and Davey M. Smith a,d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd8347cc49bc09300f5230ddaba24c6
https://pubmed.ncbi.nlm.nih.gov/27755112

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