Zobrazeno 1 - 6 of 6 pro vyhledávání: '"drug therapy, Multiple Sclerosis"'
1
Propionic Acid Rescues High-Fat Diet Enhanced Immunopathology in Autoimmunity via Effects on Th17 Responses
Autor: Linker, Ralf A., Haase, Stefanie, Mäurer, Jonas, Duscha, Alexander, Lee, De-Hyung, Balogh, Andras, Gold, Ralf, Müller, Dominik N., Haghikia, Aiden
Publikováno v: Frontiers in Immunology
Frontiers in immunology 12, 701626 (2021). doi:10.3389/fimmu.2021.701626
High-fat diets (HFD) are linked to obesity and associated comorbidities and induce pathogenic T helper (Th) 17 cells while decreasing regulatory T cells (Treg). This pro-inflammatory environment also aggravates immunopathology in experimental autoimm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90fbddd7246d55093ed5a91778f609d
http://europepmc.org/articles/PMC8204048
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2
Phase III Dose-Comparison Study of Glatiramer Acetate for Multiple Sclerosis
Autor: Comi, G, Cohen, Ja, Arnold, Dl, Wynn, D, Filippi, M, FORTE Study Group, Rocc, Ma, Perego, E, Absinta, M, Mesaros, S, Vuotto, R, Misci, P, Petrolini, M, Coyle, P, Wolinsky, J, Antel, J, Zamvil, S, Feigin, P, Carra, Aj, Bettinelli, Rj, Luetic, Gg, Vrech, Ca, Dubois, Bd, Metz, L, Bar Or, A, Bhan, V, Myles, M, Havrdova, E, Ehler, E, Kanovsky, P, Talab, R, Zapletalova, O, Gross Paju, K, Taba, P, Elovaara, I, Erälinna, Jp, Kinnunen, E, Koivisto, K, Reunanen, M, Brochet, B, Camu, W, Damier, P, Defer, G, Tumani, H, Becker, E, Buettner, T, Diener, Hc, Franz, P, Haas, J, Heesen, C, Heidenreich, F, Koelmel, Hw, Reifschneider, G, Retzlaff, K, Thoemke, F, Ziemssen, T, Rozsa, C, Bartos, L, Csanyi, A, Deme, I, Komoly, S, Panczel, G, Simo, M, Achiron, A, Milo, R, Bergamaschi, R, Bertolotto, A, Capra, R, Caputo, D, Cavalla, P, Centonze, D, Cottone, S, DE STEFANO, Nicola, Gasperini, C, Mancardi, G, Provinciali, L, Ruggieri, S, Scarpini, E, Zaffaroni, M, Metra, M, Kizlaitiene, R, Vaitkus, A, Zwanikken, Cp, Hupperts, Rm, Jongen, Pj, Szczudlik, A, Fryze, W, Kazibutowska, Z, Pierzchaa, K, Pniewski, J, Podemski, R, Stepień, A, Bajenaru, O, Campeanu, A, Marginean, I, Popescu, Cd, Toldisan, I, Boiko, A, Gustov, A, Malkova, N, Perfilyev, S, Poverennova, I, Saykhunov, M, Shutov, A, Skoromets, A, Spirin, N, Stolyarov, I, Volkova, L, Rodriguez Antigüedad, A, Arbizu, T, Arroyo, R, Barcena, J, Casanova, B, Fernández, O, Montalban, X, Ramió, L, Saiz Hinarejos, A, Sharrack, B, Silber, E, Young, C, Agius, M, Birnbaum, G, Campagnolo, D, Chaudhary, K, Cohen, J, Ford, C, Fox, E, Goodman, A, Green, B, Gupta, A, Hughes, B, Javed, A, Jeffery, D, Kasper, L, Kaufman, M, Khan, O, Kresa Reahl, K, Leist, T, Lynch, S, Markowitz, C, Mattson, D, Moses, H, Parks, B, Parry, G, Phillips, T, Picone, M, Rammohan, K, Rizvi, S, Royal, W, Scarberry, S, Sheppard, C, Simnad, V, Thrower, B, Whitham, R, Wynn, D.
Publikováno v: Annals of Neurology, 69(1), 75-82. Wiley
Objective: To evaluate the safety, tolerability, and efficacy of glatiramer acetate (GA) 40mg compared to a 20mg dose. Methods: Patients with multiple sclerosis (MS) with ≥1 documented relapse in 12 months prior to screening, or ≥2 documented rel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17bc153e00bac21f20c826009b646fc
https://doi.org/10.1002/ana.22316
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3
Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation
Autor: Josephine Herz, Agata Mossakowski, Helena Radbruch, Josef Priller, Michael Boschmann, Markus Bock, Leonard Viohl, Jenny Gerhard, Karolin Pollok, Moritz Radbruch, Florence Pache, Carmen Infante-Duarte, Anja Mähler, Janina Behrens, Daniel Bremer, Randall L. Lindquist, Raluca Niesner, Anja E. Hauser, Markus Bardua, Martina Füchtemeier, Julian Pohlan, Judith Bellmann-Strobl, Ronja Mothes, Jan Leo Rinnenthal, Friedemann Paul, Jason M. Millward
Publikováno v: Acta neuropathologica 130(6), 799-814 (2015). doi:10.1007/s00401-015-1497-x
Acta Neuropathologica
Mossakowski, A A, Pohlan, J, Bremer, D, Lindquist, R, Millward, J M, Bock, M, Pollok, K, Mothes, R, Viohl, L, Radbruch, M, Gerhard, J, Bellmann-Strobl, J, Behrens, J, Infante-Duarte, C, Mähler, A, Boschmann, M, Rinnenthal, J L, Füchtemeier, M, Herz, J, Pache, F C, Bardua, M, Priller, J, Hauser, A E, Paul, F, Niesner, R & Radbruch, H 2015, ' Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation ', Acta Neuropathologica, vol. 130, no. 6, pp. 799-814 . https://doi.org/10.1007/s00401-015-1497-x
The functional dynamics and cellular sources of oxidative stress are central to understanding MS pathogenesis but remain elusive, due to the lack of appropriate detection methods. Here we employ NAD(P)H fluorescence lifetime imaging to detect functio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2959d06d699d7087efdfe9b712adf23a
https://pub.dzne.de/record/138235
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4
False positive radiographical evidence of pump catheter migration into the spinal cord
Autor: Dardashti, Simon, Chang, Eric Y, Kim, Robert B, Alsharif, Kais I, Hata, Justin T, Perret, Danielle M
Publikováno v: Dardashti, Simon; Chang, Eric Y; Kim, Robert B; Alsharif, Kais I; Hata, Justin T; & Perret, Danielle M. (2014). False positive radiographical evidence of pump catheter migration into the spinal cord.. Pain physician, 16(5), E627-E630. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/45f0t98m
Intrathecal drug delivery systems are becoming an increasingly common modality used by physicians to treat patients. Specifically, chronic spasticity secondary to multiple sclerosis (MS) may be treated with intrathecal baclofen (ITB) therapy when ora
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::9ec64a2a84d524fee726d84adb64a173
http://www.escholarship.org/uc/item/45f0t98m
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5
Association of melanoma and natalizumab therapy in the Italian MS population: a second case report
Autor: Alice Laroni, M. Bedognetti, Elisabetta Capello, Antonio Uccelli, Gianluigi Mancardi
There is debate about a possible association between natalizumab treatment and higher risk of melanoma. Here we report a case of melanoma in a patient who developed melanoma after 77 infusions of natalizumab, without known risk factors. Pharmacovigil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dd6f886d69997a09e390e4b80e7064
https://hdl.handle.net/11567/293802
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