Zobrazeno 1 - 10
of 4 226
pro vyhledávání: '"drug research and development"'
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Single-cell multiomics (sc-multiomics) is a burgeoning field that simultaneously integrates multiple layers of molecular information, enabling the characterization of dynamic cell states and activities in development and disease as well as treatment
Externí odkaz:
https://doaj.org/article/83ca3cb2fcb04bb0bb8f5a669a44c3dd
Publikováno v:
智能科学与技术学报, Vol 6, Pp 88-99 (2024)
With the rapid development of the next generation of artificial intelligence technologies, such as the internet of things, large language models, and multimodal interactions, the traditional processes of drug research and production processing had be
Externí odkaz:
https://doaj.org/article/a8e0f68f7735457989a1e7a5be14fbeb
Autor:
Huanhuan Pang, Zeping Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3238-3251 (2023)
Emerging evidence has demonstrated the vital role of metabolism in various diseases or disorders. Metabolomics provides a comprehensive understanding of metabolism in biological systems. With advanced analytical techniques, metabolomics exhibits unpr
Externí odkaz:
https://doaj.org/article/6e7040e49e2f46088b7d1fac07814068
Autor:
Yanqiong Zhang, Xin Li, Yulong Shi, Tong Chen, Zhijian Xu, Ping Wang, Meng Yu, Wenjia Chen, Bing Li, Zhiwei Jing, Hong Jiang, Lu Fu, Wenjing Gao, Yanhua Jiang, Xia Du, Zipeng Gong, Weiliang Zhu, Hongjun Yang, Haiyu Xu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 6, Pp 2559-2571 (2023)
Existing traditional Chinese medicine (TCM)-related databases are still insufficient in data standardization, integrity and precision, and need to be updated urgently. Herein, an Encyclopedia of Traditional Chinese Medicine version 2.0 (ETCM v2.0, ht
Externí odkaz:
https://doaj.org/article/d299f57c38ca4aa287e7e5a87c02fd53
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 797 (2024)
To create a review of the published scientific literature on the benefits and potential perspectives of the use of 3D bio-nitrification in the field of pharmaceutics. This work was performed in accordance with the Preferred Reporting Items for System
Externí odkaz:
https://doaj.org/article/4da2dd71973e4e5bb842d6f167dd87de
Autor:
BAI Xiaoyin, YANG Hong
Publikováno v:
Xiehe Yixue Zazhi, Vol 14, Iss 1, Pp 81-85 (2023)
As clinical research and drug development in China continue to advance, greater attention has been paid to the value of clinical research guidelines. The first revision of the original E8 recommendations (R1), 'General Considerations for Clinical Res
Externí odkaz:
https://doaj.org/article/e846b6d7b18a4f47bcd116af40d612d4
Publikováno v:
罕见病研究, Vol 1, Iss 4, Pp 461-467 (2022)
Hemophilia is the only rare hereditary hemorrhagic disorder included in the First Rare Diseases catalogue. However, rare bleeding diseases identified in the clinic are far more common than hemophilia. Most other rare hemorrhagic disorders have less e
Externí odkaz:
https://doaj.org/article/539000e7191240d294c876e406d34337
Autor:
Pascal Mäser, Sonja Bernhard, Reto Brun, Christian Burri, Sébastien Gagneux, Manuel W. Hetzel, Marcel Kaiser, Christian Lengeler, Gerd Pluschke, Elisabeth Reus, Matthias Rottmann, Jürg Utzinger, Louisa Warryn, Sergio Wittlin, Jennifer Keiser
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
Thanks to its expertise in clinical research, epidemiology, infectious diseases, microbiology, parasitology, public health, translational research and tropical medicine, coupled with deeply rooted partnerships with institutions in low- and middle-inc
Externí odkaz:
https://doaj.org/article/0810ed06255e4e4c8ea49405fe36758f
Publikováno v:
Molecules, Vol 29, Iss 3, p 635 (2024)
Repurposing is a universal mechanism for innovation, from the evolution of feathers to the invention of Velcro tape. Repurposing is particularly attractive for drug development, given that it costs more than a billion dollars and takes longer than te
Externí odkaz:
https://doaj.org/article/4da39b3fbacc4136a7e4a5e5652f6bd2