Zobrazeno 1 - 10
of 154
pro vyhledávání: '"drug gene interactions"'
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Older patients with coronary artery disease (CAD) are particularly vulnerable to the efficacy and adverse drug reactions, and may therefore particularly benefit from personalized medication. Drug–gene interactions (DGIs) occur w
Externí odkaz:
https://doaj.org/article/350f442ffea540c9b87d2747fe66a9e2
Autor:
Sandra Knežević, Francesca Filippi-Arriaga, Andrej Belančić, Tamara Božina, Jasenka Mršić-Pelčić, Dinko Vitezić
Publikováno v:
Diabetology, Vol 5, Iss 4, Pp 406-429 (2024)
Metabolic syndrome (MetS) presents a significant global health challenge, characterized by a cluster of metabolic alterations including obesity, hypertension, insulin resistance/dysglycemia, and atherogenic dyslipidemia. Advances in understanding and
Externí odkaz:
https://doaj.org/article/b85b61eae2e541988ee76497e910e49f
Autor:
Wenxu Wang, Jincheng Lu, Ningyun Pan, Huiying Zhang, Jingcen Dai, Jie Li, Cheng Chi, Liumei Zhang, Liang Wang, Mengying Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAlzheimer’s disease (AD) is one of the most prevalent forms of dementia globally and remains an incurable condition that often leads to death. PANoptosis represents an emerging paradigm in programmed cell death, integrating three critic
Externí odkaz:
https://doaj.org/article/e6ee369291bb41c28af37399a5cbc782
Autor:
Asiimwe IG, Pirmohamed M
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 15, Pp 879-911 (2022)
Innocent G Asiimwe, Munir Pirmohamed The Wolfson Centre for Personalized Medicine, MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Live
Externí odkaz:
https://doaj.org/article/8407ba6221dc49e6a5469f5d58ae39fc
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 15, Pp 943-950 (2022)
Katie Pizzolato,1 David Thacker,2 Nicole Marie Del Toro-Pagán,1 Nishita S Amin,1 Abeer Hanna,3 Jacques Turgeon,2,4 Veronique Michaud2,4,5 1Tabula Rasa Healthcare, Office of Translational Research and Residency Programs, Moorestown, NJ, 08057, USA; 2
Externí odkaz:
https://doaj.org/article/0ded6244f01042c49fe7bffb88d76f14
Akademický článek
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Autor:
Laura M. de Jong, Soukayna Boussallami, Elena Sánchez-López, Martin Giera, Maarten E. Tushuizen, Menno Hoekstra, Lukas J. A. C. Hawinkels, Robert Rissmann, Jesse J. Swen, Martijn L. Manson
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted. Drug-drug-interaction
Externí odkaz:
https://doaj.org/article/dfd4b7aa0cba4a3db6f51c0bbc61c879
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Primary liver cancer is the sixth most commonly diagnosed cancer and the third leading cause of cancer death worldwide in 2020, and it ranks fifth in global incidence. Liver resection or liver transplantation are the two most prominent su
Externí odkaz:
https://doaj.org/article/43135512607c4f8caa478ba758632b23
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Christina Kovar, Lukas Kovar, Simeon Rüdesheim, Dominik Selzer, Boian Ganchev, Patrick Kröner, Svitlana Igel, Reinhold Kerb, Elke Schaeffeler, Thomas E. Mürdter, Matthias Schwab, Thorsten Lehr
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2604 (2022)
Clomiphene, a selective estrogen receptor modulator (SERM), has been used for the treatment of anovulation for more than 50 years. However, since (E)-clomiphene ((E)-Clom) and its metabolites are eliminated primarily via Cytochrome P450 (CYP) 2D6 and
Externí odkaz:
https://doaj.org/article/9986fda8e97f4f16bc07634d0d38153f