Zobrazeno 1 - 3
of 3
pro vyhledávání: '"drug effects [alpha-Synuclein]"'
Autor:
Pingping Song, Lena F. Burbulla, Dimitri Krainc, Jianbin Zheng, Michaela E. Johnson, Weilan Jiang, Patrik Brundin
Publikováno v:
JCI insight 6(19), e148649 (2021). doi:10.1172/jci.insight.148649
JCI Insight
JCI Insight
Current treatments for Parkinson's disease (PD) provide only symptomatic relief, with no disease-modifying therapies identified to date. Repurposing FDA-approved drugs to treat PD could significantly shorten the time needed for and reduce the costs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0e57b68f83b8651105ddd9418b71dd
https://doi.org/10.1172/jci.insight.148649
https://doi.org/10.1172/jci.insight.148649
Autor:
Günter U. Höglinger, Wolfgang Wurst, Matthias Höllerhage, Natascha Fussi, Christian Behrends, Thomas W. Rösler
Publikováno v:
Neuropharmacology 149, 13-26 (2019). doi:10.1016/j.neuropharm.2019.01.023
Pathological aggregates of alpha-synuclein are the common hallmarks of synucleinopathies, including Parkinson's disease. There is currently no disease-modifying therapy approved for neurodegenerative synucleinopathies. The induction of macroautophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625e929d4d566ceb29c99157505daf15
https://doi.org/10.1016/j.neuropharm.2019.01.023
https://doi.org/10.1016/j.neuropharm.2019.01.023
Autor:
Carlos Cordeiro, Luís M. A. Oliveira, Ruth Rott, Deborah Penque, Tania Simões, Michael Heinrich, Francesca Munari, Ekrem Darendelioglu, Olaf Riess, Carlo Breda, Diana G. Ferreira, Thomas M. Jovin, Rita Machado de Oliveira, Luísa V. Lopes, Eva F. Rodrigues, Ivo C. Martins, Hugo Vicente Miranda, Jochen Klucken, Markus Zweckstetter, Hilal A. Lashuel, Alexandre Quintas, Márcia Oliveira, Nuno C. Santos, Marcos António Gomes, Tiago F. Outeiro, Irina Zamolo, Wei Xiang, Simone Engelender, Ana Ponces-Freire, Francisco J. Enguita, Éva M. Szegö, Flaviano Giorgini
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Brain
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
Brain 140(5), 1399-1419 (2017). doi:10.1093/brain/awx056
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Brain
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
Brain 140(5), 1399-1419 (2017). doi:10.1093/brain/awx056
© The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved.
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases kn
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50ba62720be24e704cb583505996af7
