Výsledky vyhledávání - "drug effects [Ubiquitination]"

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3

Autor: Susanne Dieringer, Stephanie Dorn, Sybille Krauss, Thomas Klockgether, Katrin Zimmermann, Bernd O. Evert, Ullrich Wuellner, Alexander Pfeifer, Peter Breuer, Julieta Araujo

Publikováno v: Human molecular genetics 20(15), 2928-2941 (2011). doi:10.1093/hmg/ddr197

Ataxin-3 (ATXN3), the disease protein in spinocerebellar ataxia type 3 (SCA3), binds to target gene promoters and modulates transcription by interaction with transcriptional regulators. Here, we show that ATXN3 interacts with the forkhead box O (FOXO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc645678b79cd2b3bcdb0981f471e059
https://pubmed.ncbi.nlm.nih.gov/21536589

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