Zobrazeno 1 - 7
of 7
pro vyhledávání: '"drug effects [Transcriptome]"'
Autor:
Yvette J E Sloot, Dennis M. de Graaf, Katrin Rabold, Romana T. Netea-Maier, Bas Heinhuis, Thomas Ulas, Kristian Händler, Leo A. B. Joosten, Mihai G. Netea, Johannes W. A. Smit, Joachim L. Schultze
Publikováno v:
Cellular oncology 42(5), 691-703 (2019). doi:10.1007/s13402-019-00457-9
Cellular Oncology (2011. Print), 42, 5, pp. 691-703
Cellular Oncology (2011. Print), 42, 691-703
Cellular Oncology (2011. Print), 42, 5, pp. 691-703
Cellular Oncology (2011. Print), 42, 691-703
Interleukin 32 (IL-32) is a pro-inflammatory cytokine of which different isoforms have been identified. Recently, IL-32 has been shown to act as a potent inducer of cell migration in several types of cancer. Although previous research showed that IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40855fd955bf100a53cc1c189b844c2
https://doi.org/10.1007/s13402-019-00457-9
https://doi.org/10.1007/s13402-019-00457-9
Autor:
Andreas Dahl, Prabesh Bhattarai, Andreas Petzold, Susanne Reinhardt, Caghan Kizil, Mehmet Ilyas Cosacak, Yixin Zhang
Publikováno v:
Cell reports 27(4), 1307-1318.e3 (2019). doi:10.1016/j.celrep.2019.03.090
The neural stem cell (NSC) reservoir can be harnessed for stem cell-based regenerative therapies. Zebrafish remarkably regenerate their brain by inducing NSC plasticity in a Amyloid-β-42 (Aβ42)-induced experimental Alzheimer's disease (AD) model. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0697dcfe5d0d0254c22de0ce316e27
https://pub.dzne.de/record/140652
https://pub.dzne.de/record/140652
Autor:
Roland Benz, Martin Fuhrman, Hope Y Agbemenyah, Joon Lee, Lalit Kaurani, Gregor Eichele, Markus Zweckstetter, Gaurav Jain, Nasrollah Rezaei-Ghaleh, Andre Fischer, Alan L. Gillman, Gayane Grigorian, Ratnesh Lal, Sergey Ryazanov, Mario Caruana, Armin Giese, Christian Griesinger, Martin Korte, Eva Benito, Angelique Camilleri, Andrei Leonov, Neville Vassallo, Jens Wagner, Fernando Teran Arce, Hendrik Urbanke, Ana Martinez Hernandez, Anja Schneider, Petra Wilken
Publikováno v:
EMBO Molecular Medicine
EMBO molecular medicine 10(1), 32-47 (2018). doi:10.15252/emmm.201707825
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2018)
EMBO molecular medicine
EMBO molecular medicine, vol 10, iss 1
EMBO molecular medicine 10(1), 32-47 (2018). doi:10.15252/emmm.201707825
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2018)
EMBO molecular medicine
EMBO molecular medicine, vol 10, iss 1
Alzheimer’s disease is a devastating neurodegenerative disease eventually leading to dementia. An effective treatment does not yet exist. Here we show that oral application of the compound anle138b restores hippocampal synaptic and transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136f4a325e014173319325e91132fab8
Autor:
Seth L. Masters, Larisa I. Labzin, Dieter Lütjohann, Rainer Stahl, Joachim L. Schultze, Dominic De Nardo, Wolfgang Krebs, Eicke Latz, Susanne Schmidt, Kathrin Klee, Marc Beyer
Publikováno v:
The journal of immunology 195(9), 4446-4455 (2015). doi:10.4049/jimmunol.1500204
Cytokines and IFNs downstream of innate immune pathways are critical for mounting an appropriate immune response to microbial infection. However, the expression of these inflammatory mediators is tightly regulated, as uncontrolled production can resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8155e5809fe06772c796e66134678e9
https://doi.org/10.4049/jimmunol.1500204
https://doi.org/10.4049/jimmunol.1500204
Autor:
Marc Beyer, Lisa Schmidleithner, Jonel Trebicka, Pia Hartmann, Christian Kurts, Yasser Thabet, Philipp A. Lang, Andrea Hofmann, Annette Oxenius, Jil Sander, Jens Chemnitz, Zeinab Abdullah, Gerd Fätkenheuer, Thorsten Buch, Clara Lehmann, Joachim L. Schultze, Prashant V. Shinde, Mathias Heikenwalder, Karl S. Lang, Maren Köhne, Alexey Popov, Robert Schierwagen, Daniela Maisel, Percy A. Knolle
Publikováno v:
Nature immunology 17(5), 593-603 (2016). doi:10.1038/ni.3399
Persistent viral infections are characterized by the simultaneous presence of chronic inflammation and T cell dysfunction. In prototypic models of chronicity--infection with human immunodeficiency virus (HIV) or lymphocytic choriomeningitis virus (LC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc8e06a44bfd6d11123bc8381e5c0f2
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84960155205
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84960155205
Autor:
Magdalena Navarro-Sala, Anna-Lena Schütz, Vincenzo Capece, Camin Dean, Eva Benito, Gaurav Jain, Hendrik Urbanke, Sankari Nagarajan, Susanne Burkhardt, Stefan Bonn, Reinhardt Lührmann, Rashi Halder, Andre Fischer, Jonas Barth, Binu Ramachandran, Steven A. Johnsen, Ankit Awasthi
Publikováno v:
The journal of clinical investigation 125(9), 3572-3584 (2015). doi:10.1172/JCI79942
Journal of Clinical Investigation
Journal of Clinical Investigation
Aging and increased amyloid burden are major risk factors for cognitive diseases such as Alzheimer’s disease (AD). Effective therapies for these diseases are lacking. Here, we evaluated mouse models of age-associated memory impairment and amyloid d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e520081479caf842bf319aca308274
A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking
Autor:
Roby Joehanes, George T. O'Connor, Uwe Völker, Dawn L. DeMeo, Dena G. Hernandez, L Ferrucci, Marjolein J. Peters, Christian Herder, Daniel Levy, Alexander Teumer, Hans J. Grabe, Tõnu Esko, Andres Metspalu, Tianxiao Huan, Melanie Waldenberger, Emelia J. Benjamin, Katharina Schramm, Sonja Zeilinger, Georg Homuth, Luke C. Pilling, Joyce B. J. van Meurs, Holger Prokisch, Albert Hofman, Honghuang Lin, Peter J. Munson, Claudia Schurmann, Andrew B. Singleton, André G. Uitterlinden, Reedik Mägi, Reiner Biffar, Annette Peters, David Melzer, Stefania Bandinelli
Publikováno v:
Human Molecular Genetics
Human molecular genetics 25(21), ddw288 (2016). doi:10.1093/hmg/ddw288
Human molecular genetics 25(21), ddw288 (2016). doi:10.1093/hmg/ddw288
Cigarette smoking is a leading modifiable cause of death worldwide. We hypothesized that cigarette smoking induces extensive transcriptomic changes that lead to target-organ damage and smoking-related diseases. We performed a metaanalysis of transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f25e6a2d19c5bb237128ea1b614e1a
https://doi.org/10.1093/hmg/ddw288
https://doi.org/10.1093/hmg/ddw288