Zobrazeno 1 - 6
of 6
pro vyhledávání: '"drug effects [Down-Regulation]"'
Autor:
Sónia Sá Santos, João B. Moreira, Márcia Costa, Rui S. Rodrigues, Ana M. Sebastião, Sara Xapelli, Susana Solá
Publikováno v:
Cells, Vol 11, Iss 90, p 90 (2022)
Cells
Cells; Volume 11; Issue 1; Pages: 90
Cells 11(1), 90 (2021). doi:10.3390/cells11010090 special issue: "Mitochondrial Functions in Stem Cells"
Cells
Cells; Volume 11; Issue 1; Pages: 90
Cells 11(1), 90 (2021). doi:10.3390/cells11010090 special issue: "Mitochondrial Functions in Stem Cells"
Neural stem cells (NSCs), crucial for memory in the adult brain, are also pivotal to buffer depressive behavior. However, the mechanisms underlying the boost in NSC activity throughout life are still largely undiscovered. Here, we aimed to explore th
Autor:
S Cantilena, Stefanie Meier, Darren Hargrave, David Michod, John Anderson, Jasper de Boer, Maria Victoria Niklison Chirou, Paolo Salomoni
Publikováno v:
Cell Death & Disease
Cell death & disease 12(8), 785 (2021). doi:10.1038/s41419-021-04078-9
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell death & disease 12(8), 785 (2021). doi:10.1038/s41419-021-04078-9
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Pediatric gliomas comprise a broad range of brain tumors derived from glial cells. While high-grade gliomas are often resistant to therapy and associated with a poor outcome, children with low-grade gliomas face a better prognosis. However, the treat
Autor:
Wei-Hua Chiu, Thomas Carlsson, Eberhard Weihe, Martin Klietz, Günter U. Höglinger, Candan Depboylu, Ursula Keber, Martin K.-H. Schäfer
Publikováno v:
Neuroscience 331, 120-133 (2016). doi:10.1016/j.neuroscience.2016.06.017
l-3,4-Dihydroxyphenylalanine (l-DOPA) is the therapeutic gold standard in Parkinson's disease. However, most patients develop debilitating abnormal involuntary movements termed l-DOPA-induced dyskinesia (LID) as therapy-complicating side effects. The
Autor:
Sabina Honisch, Ludger Schoels, Christos Stournaras, Florian Lang, Basma Sukkar, Itishri Sahu, Andreas Hermann, Lisann Pelzl, Alexander Storch, Yogesh Singh, Bhaeldin Elsir, Elisabeth Lang, Mohamed Jemaà, Rosi Bissinger
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 5, Pp 2066-2077 (2017)
Cellular physiology and biochemistry 42(5), 2066-2077 (2017). doi:10.1159/000479901
Cellular physiology and biochemistry 42(5), 2066-2077 (2017). doi:10.1159/000479901
Background: The widely expressed protein chorein fosters activation of the phosphoinositide 3 kinase (PI3K) pathway thus supporting cell survival. Loss of function mutations of the chorein encoding gene VPS13A (vacuolar protein sorting-associated pro
Autor:
Alexander Pfeifer, Jennifer Naumann, Andreas Schlitzer, Anna Ehrlund, Peter Arner, Abhishek Sanyal, Agnieszka Chabowska-Kita, Matthias Blüher, Linda S. Hoffmann
Publikováno v:
Cell reports 18(1), 225-236 (2017). doi:10.1016/j.celrep.2016.12.028
Current worldwide figures suggest that obesity is pandemic. Understanding the underlying molecular mechanisms would help develop viable anti-obesity therapies. Here, we assess the influence of obesity-induced inflammation on white adipocyte cyclic gu
Autor:
Albert J. Becker, Susanne Schoch, Heinz Beck, Anne Woitecki, Tony Kelly, Thoralf Opitz, David M. Otte, Julika Pitsch, Michel Royeck, Ulrich Benjamin Kaupp, Andreas Rennhack, Yoel Yaari, Andreas Zimmer
Publikováno v:
The journal of neuroscience 35(46), 15240-15253 (2015). doi:10.1523/JNEUROSCI.0493-15.2015
Dendritic voltage-gated ion channels profoundly shape the integrative properties of neuronal dendrites. In epilepsy, numerous changes in dendritic ion channels have been described, all of them due to either their altered transcription or phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ed454b97966ab8020c772c8fee6fb7
https://pub.dzne.de/record/138257
https://pub.dzne.de/record/138257