Zobrazeno 1 - 5
of 5
pro vyhledávání: '"drug effects [Cytoskeleton]"'
Autor:
Bert Klebl, Martin Stehling, Lara Marrone, Peter Nussbaumer, Masin Abo-Rady, Antje Janosch, Jan Eickhoff, Matthias Baumann, Eric N. Anderson, Guruchandar Arulmozhivarman, Gunther Zischinsky, Kenjiro Adachi, Sascha Menninger, Marc Bickle, Peter Reinhardt, Claudia Fröb, Hannes C.A. Drexler, Michell M. Reimer, Jared Sterneckert, Michael Glatza, Susanne Kordes, Prabesh Bhattarai, Udai Bhan Pandey, Caghan Kizil, Lydia Reinhardt, Hans R. Schöler
Publikováno v:
Stem Cell Reports
Stem cell reports 12(3), 502-517 (2019). doi:10.1016/j.stemcr.2019.01.015
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Stem cell reports 12(3), 502-517 (2019). doi:10.1016/j.stemcr.2019.01.015
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Summary Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a62262d3eda3ad763fb4978fc17dde
Autor:
Janaky Coomaraswamy, Frank Gillardon, Marta Garcia-Miralles, Mathias Jucker, Saskia Biskup, Dagmar Galter, Karina Häbig, Martina Maisel, Natalja Funk, Martin C. Herzig, Thomas Gasser
Publikováno v:
PLoS ONE
PLOS ONE 10(4), e0118947 (2015). doi:10.1371/journal.pone.0118947
PLoS ONE, Vol 10, Iss 4, p e0118947 (2015)
PLOS ONE 10(4), e0118947 (2015). doi:10.1371/journal.pone.0118947
PLoS ONE, Vol 10, Iss 4, p e0118947 (2015)
Mutations within the LRRK2 gene have been identified in Parkinson's disease (PD) patients and have been implicated in the dysfunction of several cellular pathways. Here, we explore how pathogenic mutations and the inhibition of LRRK2 kinase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7e6cdd8399aefb612e7e411bdcf9e4
http://europepmc.org/articles/PMC4382199
http://europepmc.org/articles/PMC4382199
Publikováno v:
Journal of bioenergetics and biomembranes
Soy isoflavones are diphenolic compounds that are frequently used for alternative treatment of ageing symptoms in both genders. They operate at principally two hierarchical levels of functional organization - cellular and molecular, while these 'type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949cd76cfbe30771477c2e4b851579ac
https://pubmed.ncbi.nlm.nih.gov/24346760
https://pubmed.ncbi.nlm.nih.gov/24346760
Autor:
Eva-Maria Mandelkow, Hans Zempel
Publikováno v:
Neurodegenerative diseases 10(1-4), 64-72 (2012). doi:10.1159/000332816
Neurodegenerative Diseases
Neurodegenerative Diseases
Background: In Alzheimer’s disease (AD), amyloid-β (Aβ) is the major component of extracellular plaques, whereas the microtubule-associated protein tau forms the main component of intracellular tangles. In contrast to frontotemporal dementias and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf637e835e667b86b80e06e375441e2
https://pubmed.ncbi.nlm.nih.gov/22156588
https://pubmed.ncbi.nlm.nih.gov/22156588
