Zobrazeno 1 - 10
of 10
pro vyhledávání: '"drug effects [Cell Movement]"'
Autor:
Yvette J E Sloot, Dennis M. de Graaf, Katrin Rabold, Romana T. Netea-Maier, Bas Heinhuis, Thomas Ulas, Kristian Händler, Leo A. B. Joosten, Mihai G. Netea, Johannes W. A. Smit, Joachim L. Schultze
Publikováno v:
Cellular oncology 42(5), 691-703 (2019). doi:10.1007/s13402-019-00457-9
Cellular Oncology (2011. Print), 42, 5, pp. 691-703
Cellular Oncology (2011. Print), 42, 691-703
Cellular Oncology (2011. Print), 42, 5, pp. 691-703
Cellular Oncology (2011. Print), 42, 691-703
Interleukin 32 (IL-32) is a pro-inflammatory cytokine of which different isoforms have been identified. Recently, IL-32 has been shown to act as a potent inducer of cell migration in several types of cancer. Although previous research showed that IL-
Autor:
Sai-Yang Zhang, Yu-Hui Hou, Ping Li, Ying-Chao Liu, Cheng-Yun Jin, Ruo-Han Zhao, Hong-Min Liu, Xiaolin Zi, Ruo-Wang Mao, Dong-Jun Fu, Jia-Jia Yang, Jian Song, Yan-Bing Zhang, Zhang Li, Jia-Huan Li
Publikováno v:
Fu, Dong-Jun; Zhang, Li; Song, Jian; Mao, Ruo-Wang; Zhao, Ruo-Han; Liu, Ying-Chao; et al.(2017). Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.. European journal of medicinal chemistry, 127, 87-99. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/2jw7m037
A series of novel formononetin-dithiocarbamate derivatives were designed, synthesized and evaluated for antiproliferative activity against three selected cancer cell line (MGC-803, EC-109, PC-3). The first structure-activity relationship (SAR) for th
Autor:
Ruschel, Jörg, Hellal, Farida, Peitz, Michael, Brüstle, Oliver, Norenberg, Michael D, Blesch, Armin, Weidner, Norbert, Bunge, Mary Bartlett, Bixby, John L, Bradke, Frank, Flynn, Kevin C, Dupraz, Sebastian, Elliott, David A, Tedeschi, Andrea, Bates, Margaret, Sliwinski, Christopher, Brook, Gary, Dobrindt, Kristina
Publikováno v:
Science / Science now 348(6232), 347-352 (2015). doi:10.1126/science.aaa2958
After central nervous system (CNS) injury, inhibitory factors in the lesion scar and poor axon growth potential prevent axon regeneration. Microtubule stabilization reduces scarring and promotes axon growth. However, the cellular mechanisms of this d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10678::75fc9425e0a9cf5626c9fd506b6e57d1
https://pub.dzne.de/record/137893
https://pub.dzne.de/record/137893
Autor:
Beatrix Bartok, William B. Kiosses, Nikolaos Mitakidis, Nunzio Bottini, David L. Boyle, Jeffrey D. Esko, Mattias Svensson, Gary S. Firestein, Ru Liu-Bryan, Esther Cory, Camille Fos, Stephanie M. Stanford, Robert L. Sah, Tomas Mustelin, Heather A. Arnett, C.H. Coles, Michel L. Tremblay, Karen M. Doody, Maripat Corr, Cristiano Sacchetti, A. Radu Aricescu
Publikováno v:
Science translational medicine 7(288), 288ra76-288ra76 (2015). doi:10.1126/scitranslmed.aaa4616
Science translational medicine, vol 7, iss 288
Science translational medicine, vol 7, iss 288
Despite the availability of several therapies for rheumatoid arthritis (RA) that target the immune system, a large number of RA patients fail to achieve remission. Joint-lining cells, called fibroblast-like synoviocytes (FLS), become activated during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412744d5cefd3ee5f48ca9e47b78e31d
Autor:
Adriana Albini, Antonino Bruno, Cristina Gallo, Barbara Bassani, Laura Vera, Enrico A. Stura, Vincent Dive, Armando Rossello, Tiziano Tuccinardi, Caterina Camodeca, Susanna Nencetti, Adriano Martinelli, Anna Rita Cantelmo, Elisabetta Orlandini, Elisa Nuti
Matrix metalloproteinases (MMPs) have been shown to be involved in tumor-induced angiogenesis. In particular, MMP-2, MMP-9, and MMP-14 have been reported to be crucial for tumor angiogenesis and the formation of metastasis, thus becoming attractive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c53e7a12a82a118f6df3c7492649cf6
http://hdl.handle.net/11568/755208
http://hdl.handle.net/11568/755208
Autor:
Heiko Backes, Roland T. Ullrich, Michael Schroeter, Beata Emig, Marie-Lune Simard, Bernd Neumaier, Rudolf Graf, Mathias Hoehn, Gereon R. Fink, Maria Adele Rueger, Maureen Walberer
Publikováno v:
The journal of neuroscience 30, 6454-6460 (2010). doi:10.1523/JNEUROSCI.6092-09.2010
Neural stem cells reside in two major niches in the adult brain [i.e., the subventricular zone (SVZ) and the dentate gyrus of the hippocampus]. Insults to the brain such as cerebral ischemia result in a physiological mobilization of endogenous neural
Autor:
Tommy Regen, Daniel Jardanhazi-Kurutz, Fabian Nadrigny, Uwe-Karsten Hanisch, Markus P. Kummer, Lucia Dumitrescu-Ozimek, Michael T. Heneka, Ana Martinez-Hernandez, Frank Kirchhoff, Jochen Walter, Dick Terwel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 107(13), 6058-6063 (2010). doi:10.1073/pnas.0909586107
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Locus ceruleus (LC)-supplied norepinephrine (NE) suppresses neuroinflammation in the brain. To elucidate the effect of LC degeneration and subsequent NE deficiency on Alzheimer's disease pathology, we evaluated NE effects on microglial key functions.
Autor:
Renata C. O. Zanardo, Vincenzo Brancaleone, Eleonora Distrutti, Stefano Fiorucci, Giuseppe Cirino, John L. Wallace
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(12)
Hydrogen sulfide (H2S) is increasingly recognized as an important signaling molecule in the cardiovascular and nervous systems. Recently, H2S donors were reported to induce neutrophil apoptosis and to suppress expression of some leukocyte and endothe
Autor:
Loitto, Vesa-Matti
Publikováno v:
Sammanfattning och ramberättelse från Linköping University Electronic Press.
Diss. (sammanfattning) Linköping : Univ., 2001.
Härtill 4 uppsatser.
Härtill 4 uppsatser.
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5142
Publikováno v:
Journal of cellular physiology. 151(1)
The data reported were obtained as an attempt to understand whether the change in total concentration and relative ratios of the 3 major corneal gangliosides (GM3, GM2, GD3) previously observed in corneas stimulated by an angiogenic molecule (Ziche e