Zobrazeno 1 - 1
of 1
pro vyhledávání: '"drug effects/genetics/physiology, Plaque"'
Autor:
Marina Pizzi, Claudia Balducci, Luciana Giardino, Alessandro Usiello, Arturo R. Viscomi, Gino Villetti, Giuseppe Nisticò, Bruno P. Imbimbo, Annamaria Lanzillotta, Gianluigi Forloni, Luca Lorenzini, Alessandro Giuliani, Ilenia Sarnico, Lydia Mare, Simone Ottonello, Sandra Sivilia, Laura Calzà, Bisan Mehdawy, Robert Nisticò
Publikováno v:
Journal of Alzheimer's Disease. 24:799-816
Abnormal amyloid-β (Aβ) production and deposition is believed to represent one of the main causes of Alzheimer's disease (AD). γ-Secretase is the enzymatic complex responsible for Aβ generation from its precursor protein. Inhibition or modulation