Zobrazeno 1 - 10
of 107
pro vyhledávání: '"drug affinity responsive target stability"'
Autor:
Feiyan Chen, Wenjing Zhang, Shuyi Xu, Hantao Zhang, Lin Chen, Cuihua Chen, Zhu Zhu, Yunan Zhao
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 5, Pp 662-671 (2023)
Background: 20(S)-protopanaxadiol (PPD), a ginsenoside metabolite, has prominent benefits for the central nervous system, especially in improving learning and memory. However, its transcriptional targets in brain tissue remain unknown. Methods: In th
Externí odkaz:
https://doaj.org/article/a57d3b94de6347e9ad39e2b20a979407
Autor:
Sara Ceccacci, Lorenzo Corsi, Lucio Spinelli, Clarissa Caroli, Matilde Marani, Lisa Anceschi, Matteo Mozzicafreddo, Federica Pellati, Maria Chiara Monti
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e24196- (2024)
The discovery of the interactome of cannabidiol (CBD), a non-psychoactive cannabinoid from Cannabis sativa L., has been here performed on chronic myelogenous leukemia cancer cells, using an optimized chemo-proteomic stage, which links Drug Affinity R
Externí odkaz:
https://doaj.org/article/d9cdc5d02eb2449ba8963e7017d67394
Autor:
Zhu Zhu, Ruimei Li, Wei Qin, Hantao Zhang, Yao Cheng, Feiyan Chen, Cuihua Chen, Lin Chen, Yunan Zhao
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 6, Pp 750-758 (2022)
Background: Mild cognitive impairment (MCI) is a transitional condition between normality and dementia. Ginseng is known to have effects on attenuating cognitive deficits in neurogenerative diseases. Ginsenosides are the main bioactive component of g
Externí odkaz:
https://doaj.org/article/44791450a4d645438346292b222717d5
Autor:
Elva Morretta, Alessandra Capuano, Gilda D’Urso, Antonia Voli, Matteo Mozzicafreddo, Sonia Di Gaetano, Domenica Capasso, Marina Sala, Maria Carmina Scala, Pietro Campiglia, Vincenzo Piccialli, Agostino Casapullo
Publikováno v:
Marine Drugs, Vol 22, Iss 2, p 52 (2024)
Mycalin A (MA) is a polybrominated C-15 acetogenin isolated from the marine sponge Mycale rotalis. Since this substance displays a strong antiproliferative bioactivity towards some tumour cells, we have now directed our studies towards the elucidatio
Externí odkaz:
https://doaj.org/article/d3bcb947622e471cb92c1be4ff94271d
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 15, Pp 4649-4664 (2021)
Jinxia Wei,* Simiao Fan,* Hongxin Yu,* Lexin Shu, Yubo Li School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China*These authors contributed equally to this workCorres
Externí odkaz:
https://doaj.org/article/5c5da8d73e0941e58922a08cbfac0d3d
Autor:
Giusy Ferraro, Raffaella Belvedere, Antonello Petrella, Alessandra Tosco, Björn Stork, Stefano Salamone, Alberto Minassi, Federica Pollastro, Elva Morretta, Maria Chiara Monti
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Artemetin is a valuable 5-hydroxy-3,6,7,3′,4′-pentamethoxyflavone present in many different medicinal plants with very good oral bioavailability and drug-likeness values, owing to numerous bioactivities, such as anti-inflammatory and anti-cancer
Externí odkaz:
https://doaj.org/article/75995245eb844cd7905f4c47e674e31f
Akademický článek
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Autor:
Yang Yang, Lijing Zhang, Jiaojiao Yu, Zhaobin Ma, Moxiang Li, Jin Wang, Pengcheng Hu, Jia Zou, Xueying Liu, Ying Liu, Su An, Cheng Xiang, Xiaoxi Guo, Qian Hao, Tian-Rui Xu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The serotonin receptor 5-HT1B is widely expressed in the central nervous system and has been considered a drug target in a variety of cognitive and psychiatric disorders. The anti-inflammatory effects of 5-HT1B agonists may present a promising approa
Externí odkaz:
https://doaj.org/article/3568cc1e86a74d6f9d20a611a6b50b79
Akademický článek
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Akademický článek
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