Zobrazeno 1 - 10
of 197
pro vyhledávání: '"drug–disease association"'
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Motivation Computational techniques for drug-disease prediction are essential in enhancing drug discovery and repositioning. While many methods utilize multimodal networks from various biological databases, few integrate comprehensive multi-
Externí odkaz:
https://doaj.org/article/d6551e4582384ec6bf08a983ed7fe1bc
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Conducting traditional wet experiments to guide drug development is an expensive, time-consuming and risky process. Analyzing drug function and repositioning plays a key role in identifying new therapeutic potential of approved dr
Externí odkaz:
https://doaj.org/article/6f22110af321478f8be2cb5e6eae81e8
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Accurately identifying novel indications for drugs is crucial in drug research and discovery. Traditional drug discovery is costly and time-consuming. Computational drug repositioning can provide an effective strategy for discovering potential drug-d
Externí odkaz:
https://doaj.org/article/1bf5fe6e14924dfe89a38e36bf98e381
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 8, Pp 14136-14157 (2023)
Drugs, which treat various diseases, are essential for human health. However, developing new drugs is quite laborious, time-consuming, and expensive. Although investments into drug development have greatly increased over the years, the number of drug
Externí odkaz:
https://doaj.org/article/0e0d9514e78e45f2a96c61cd6ea66156
Autor:
Xianbin Li, Minzhen Liao, Bing Wang, Xiangzhen Zan, Yanhao Huo, Yue Liu, Zhenshen Bao, Peng Xu, Wenbin Liu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4446-4455 (2023)
Numerous computational drug repurposing methods have emerged as efficient alternatives to costly and time-consuming traditional drug discovery approaches. Some of these methods are based on the assumption that the candidate drug should have a reversa
Externí odkaz:
https://doaj.org/article/92d29c109e874640ad6beafdff8b77b6
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Associations of drugs with diseases provide important information for expediting drug development. Due to the number of known drug-disease associations is still insufficient, and considering that inferring associations between the
Externí odkaz:
https://doaj.org/article/e106b9cb407142eeaf61450b7188be6d
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Drug repositioning is a very important task that provides critical information for exploring the potential efficacy of drugs. Yet developing computational models that can effectively predict drug–disease associations (DDAs) is s
Externí odkaz:
https://doaj.org/article/27877126b0854d818a1380382ec9d851
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