Zobrazeno 1 - 10
of 442
pro vyhledávání: '"drd3"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cariprazine (CAR) is an antipsychotic drug for the treatment of schizophrenia (SCZ) and bipolar disorder (BD), and it acts as a partial agonist on the dopamine receptors (DR), D2, and D3. Although many single nucleotide polymorphisms (SNPs) in genes
Externí odkaz:
https://doaj.org/article/18a7dc3784b342e88e1dfac8ab5da6af
Autor:
Sercan Kenanoglu, Nefise Kandemir, Hilal Akalin, Nuriye Gokce, Mehmet F. Gol, Murat Gultekin, Emel Koseoglu, Meral Mirza, Munis Dundar
Publikováno v:
Global Medical Genetics, Vol 09, Iss 02, Pp 110-117 (2022)
Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by a devastating decline in cognitive activities among all types of dementia, and it severely affects the quality of life. Late-onset AD (LOAD) occurs after the age of 65 y
Externí odkaz:
https://doaj.org/article/fea7d10320434afa9b4d38812a9f4f31
Publikováno v:
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, Vol 55, Iss 4, Pp 15-35 (2021)
Antipsychotic-induced parkinsonism is an undesirable reaction from the extrapyramidal system that occurs against the background of taking antipsychotics (AP), more often in patients with schizophrenia. Antipsychotic-induced parkinsonism belongs to th
Externí odkaz:
https://doaj.org/article/fb2da91eb00c4ca09c7dbb2dffa4a719
Publikováno v:
Kybernetes, 2020, Vol. 50, Issue 5, pp. 1566-1587.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/K-03-2020-0138
Autor:
Tatyana G. Govorova, Tatyana E. Popova, Alexey A. Tappakhov, Polina I. Golikova, Anastasya L. Danilova, Ulyana D. Antipina, Vera N. Samorseva, Alena Yu. Petrova, Michil E. Andreev, Nadezhda N. Lyasheeva
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 14, Iss 1, Pp 55-61 (2020)
Introduction. The ETM1, ETM2 and ETM3 loci are linked with the development of essential tremor (ET). It has been established that a mutation in the LINGO1 gene is a significant risk factor for ET development. The aim of the study was to investigat
Externí odkaz:
https://doaj.org/article/682a9ca14df543e69b4511765beee543
Autor:
Souhir Mestiri, Sami Boussetta, Andrew J. Pakstis, Sarra El Kamel, Amel Ben Ammar El Gaaied, Kenneth K. Kidd, Lotfi Cherni
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Background The single nucleotide polymorphisms (SNPs) of the dopamine D3 receptor (DRD3), the CUB and sushi multiple domains 1 (CSMD1) and the neuregulin 1 (NRG1) genes were used to study the genetic diversity and affinity among North Africa
Externí odkaz:
https://doaj.org/article/907bcba05ac74c1790c6ba8093f328c2
Autor:
Anna Morozova, Yana Zorkina, Konstantine Pavlov, Olga Pavlova, Olga Abramova, Valeria Ushakova, Alexander V. Mudrak, Svetlana Zozulya, Irina Otman, Zoya Sarmanova, Tatiana Klyushnik, Alexander Reznik, Georgiy Kostyuk, Vladimir Chekhonin
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
We investigated the associations of DRD3 rs6280, HTR1A rs6295, BDNF rs6265, SCL6A4 rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and associations of these genetic variants with several clinical features. We also invest
Externí odkaz:
https://doaj.org/article/d029231dcf5c40c7a1f1cd896e29c51b
Autor:
Marjorie C. Gondré-Lewis, Igor Elman, Tanya Alim, Edwin Chapman, Beverlyn Settles-Reaves, Carine Galvao, Mark S. Gold, David Baron, Shan Kazmi, Eliot Gardner, Ashim Gupta, Catherine Dennen, Kenneth Blum
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 870 (2022)
While opioids are a powerful class of drugs that inhibit transmission of pain signals, their use is tarnished by the current epidemic of opioid use disorder (OUD) and overdose deaths. Notwithstanding published reports, there remain gaps in our knowle
Externí odkaz:
https://doaj.org/article/869b9e64f6114215aa84ec363c2f2d17
Autor:
Nefise Kandemir, Murat Gultekin, Mehmet Kara, Arslan Bayram, Nazife Tascioglu, Meral Mirza, Munis Dundar
Publikováno v:
Universa Medicina, Vol 39, Iss 2 (2020)
Background Essential tremor (ET) is the most common disease among movement disorders. Genes such as essential tremor 1-4 (ETM 1-4), HS1-binding protein-3 (HS1BP3), dopamine receptor D3 (DRD3), leucine-rich repeat and Ig domain containing 1 (LINGO1),
Externí odkaz:
https://doaj.org/article/e978076b54804de4a49ce199787c8dc6
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Chondrosarcoma is the second most common malignant bone tumor. Current therapies remain ineffective, resulting in poor prognoses. Biomarkers for chondrosarcoma and predictors of its prognosis have not been established. Mental health–related protein
Externí odkaz:
https://doaj.org/article/c91340c815f14f14a4d44e59ede486e2