Brain insulin resistance in Down syndrome: Involvement of PI3K-Akt/mTOR axis in early-onset of Alzheimer's disease and its potential as a therapeutic target.

Autor: Azimzadeh M; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Cheah PS; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; Malaysian Research Institute on Ageing (MyAgeing®), Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Electronic address: cheahpikesee@upm.edu.my., Ling KH; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; Malaysian Research Institute on Ageing (MyAgeing®), Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Electronic address: lkh@upm.edu.my.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Nov 12; Vol. 733, pp. 150713. Date of Electronic Publication: 2024 Sep 17.

Dermatologic Conditions in Down Syndrome: A Multi-Site Retrospective Review of International Classification of Diseases Codes.

Autor: Rakasiwi T; Department of Dermatology, Dartmouth Health, Manchester, New Hampshire, USA., Ryan C; Geisel Medical School, Hanover, New Hampshire, USA., Stein A; Pediatric Dermatology Research Alliance, Portland, Oregon, USA., Vu A; Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Dykman M; University of Minnesota Medical School, Minneapolis, Minnesota, USA., Shah I; Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Reilly C; Georgetown University School of Medicine, Washington, DC, USA., Brokamp G; Ohio State University Wexner Medical Center, Columbus, Ohio, USA., Mologousis MA; Tufts University School of Medicine, Boston, Massachusetts, USA., Komishke B; Division of Dermatology, The Hospital for Sick Children, Toronto, Ontario, Canada., Hou V; University of Colorado Medical School, Aurora, Colorado, USA., Maguiness S; Department of Dermatology, M Health Fairview, Minneapolis, Minnesota, USA., Kirkorian AY; Division of Dermatology, Children's National Hospital, Washington, DC, USA.; George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Price H; Division of Dermatology, Phoenix Children's Hospital, Phoenix, Arizona, USA., Hawryluk EB; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA., Fernandez Faith E; Division of Dermatology, Nationwide Children's Hospital, Columbus, Ohio, USA., Lara-Corrales I; Division of Dermatology, The Hospital for Sick Children, Toronto, Ontario, Canada., Gurnee E; Department of Dermatology, University of Colorado, Aurora, Colorado, USA., Holland KE; Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Rork JF; Department of Dermatology, Dartmouth Health, Manchester, New Hampshire, USA.; Department of Pediatrics, Dartmouth Health, Manchester, New Hampshire, USA.

Publikováno v: Pediatric dermatology [Pediatr Dermatol] 2024 Nov-Dec; Vol. 41 (6), pp. 1047-1052. Date of Electronic Publication: 2024 Sep 26.

JAK inhibition in Down Syndrome Regression Disorder.

Autor: Rachubinski AL; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, 12700 East 19(th) Avenue, Aurora, CO 80045, United States; Department of Pediatrics, Section of Developmental Pediatrics, University of Colorado Anschutz Medical Campus, 13123 E. 16(th) Ave. B065 Aurora, CO 80045, United States. Electronic address: angela.rachubinski@cuanschutz.edu., Patel LR; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, 12700 East 19(th) Avenue, Aurora, CO 80045, United States., Sannar EM; Department of Psychiatry, University of Colorado Anschutz Medical Campus, 13123 E. 16(th) Ave. Aurora, CO 80045, United States., Kammeyer RM; Department of Neurology, Section of Neuroimmunology, University of Colorado School of Medicine 13123 E. 16(th) Ave. Aurora, CO 80045, United States., Sanders J; Department of Pediatrics, Section of Developmental Pediatrics, University of Colorado Anschutz Medical Campus, 13123 E. 16(th) Ave. B065 Aurora, CO 80045, United States., Enriquez-Estrada BA; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, 12700 East 19(th) Avenue, Aurora, CO 80045, United States., Worek KR; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, 12700 East 19(th) Avenue, Aurora, CO 80045, United States., Fidler DJ; Human Development and Family Studies, Colorado State University, 313 Behavioral Sciences, Fort Collins, CO 80523, United States., Santoro JD; Division of Neurology, Department of Pediatrics, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS82 Los Angeles, CA 90027, United States; Department of Neurology, Keck School of Medicine at the University of Southern California, 1520 San Pablo St, Los Angeles, CA 90033, United States., Espinosa JM; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, 12700 East 19(th) Avenue, Aurora, CO 80045, United States; Department of Pharmacology, University of Colorado Anschutz Medical Campus, 12800 East 19(th) Avenue 6126 Aurora, CO 80045, United States. Electronic address: joaquin.espinosa@cuanschutz.edu.

Publikováno v: Journal of neuroimmunology [J Neuroimmunol] 2024 Oct 15; Vol. 395, pp. 578442. Date of Electronic Publication: 2024 Aug 22.

Trisomy 21 and Congenital Heart Disease: Impact on Health and Functional Outcomes From Birth Through Adolescence: A Scientific Statement From the American Heart Association.

Autor: Peterson JK, Clarke S, Gelb BD, Kasparian NA, Kazazian V, Pieciak K, Pike NA, Setty SP, Uveges MK, Rudd NA

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2024 Oct; Vol. 13 (19), pp. e036214. Date of Electronic Publication: 2024 Sep 12.

Adenotonsillectomy outcomes in children with down syndrome and obstructive sleep apnea: a single center study.

Autor: Senthilvel E; Department of Pediatrics, University of Louisville and Norton Children Medical Group, 9880 Angies Way Suite 300, Louisville, KY, KY40241, USA. Egambaram.senthilvel@louisville.edu., Jawad K; Department of Pediatrics, Norton Children's Research Institute, Affiliated with University of Louisville School of Medicine, Louisville, Kentucky, USA., Gearhart AM; Department of Pulmonary, Critical Care and Sleep Medicine, Oklahoma State University, Tulsa, OK, USA., Naidugari JR; University of Louisville School of Medicine, Louisville, Kentucky,, USA., El-Kersh K; Department of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Arizona College of Medicine, Phoenix, Arizona, USA.

Publikováno v: Sleep & breathing = Schlaf & Atmung [Sleep Breath] 2024 Oct; Vol. 28 (5), pp. 2213-2221. Date of Electronic Publication: 2024 Jun 19.