Zobrazeno 1 - 10
of 238
pro vyhledávání: '"double-stranded breaks"'
Autor:
Maiko Kitaoka, Yukiko M. Yamashita
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
ABSTRACTSpecies’ continuity depends on gametogenesis to produce the only cell types that can transmit genetic information across generations. Spermiogenesis, which encompasses post-meiotic, haploid stages of male gametogenesis, is a process that le
Externí odkaz:
https://doaj.org/article/00dc7ae8835f4c7fa15e2cd8fabda848
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2024)
Root and tuber crops (RTCs), which include cassava, potato, sweet potato, and yams, principally function as staple crops for a considerable fraction of the world population, in addition to their diverse applications in nutrition, industry, and bioene
Externí odkaz:
https://doaj.org/article/d08b62b45f414f8dab1274d454142650
Autor:
Madhumanti Barman, Debabrata Dandasena, Akash Suresh, Vasundhra Bhandari, Sonam Kamble, Sakshi Singh, Madhusmita Subudhi, Paresh Sharma
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Bovine theileriosis caused by the eukaryotic parasite Theileria annulata is an economically important tick-borne disease. If it is not treated promptly, this lymphoproliferative disease has a significant fatality rate. Buparvaquon
Externí odkaz:
https://doaj.org/article/3fb62d09bc254745b357b99f50d6c361
Autor:
Nikolay V. Goncharov, Valeria A. Kovalskaia, Alexander O. Romanishin, Nikita A. Shved, Andrei S. Belousov, Vladlena S. Tiasto, Valeriia S. Gulaia, Vidushi S. Neergheen, Nawraj Rummun, Mikhail Liskovykh, Vladimir Larionov, Natalay Kouprina, Vadim V. Kumeiko
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Human artificial chromosomes (HACs) have provided a useful tool to study kinetochore structure and function, gene delivery, and gene expression. The HAC propagates and segregates properly in the cells. Recently, we have developed an experimental high
Externí odkaz:
https://doaj.org/article/939e5a9d4efb4137a2722f530ed11179
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, Vol 29, Iss 1, Pp 87-95 (2021)
Introduction: Gastritis is one of the most common diseases affecting the stomach. Helicobacter pylori infection could lead to DNA damage in gastric epithelial cells, followed by error-prone DNA repair pathways that increase the accumulation of damage
Externí odkaz:
https://doaj.org/article/f9a4b2ee4c1d4b0485c2b0d43e91242c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7041 (2023)
The Ku heterodimer, composed of subunits Ku70 and Ku80, is known for its essential role in repairing double-stranded DNA breaks via non-homologous end joining (NHEJ). We previously identified Ku70 S155 as a novel phosphorylation site within the von W
Externí odkaz:
https://doaj.org/article/7334146d3fdc43e4a2fb1a6802a24cc4
Autor:
G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 6, Pp 643-652 (2020)
The paper describes some biological features of the radioprotective effect of double-stranded RNA preparation. It was found that yeast RNA preparation has a prolonged radioprotective effect after irradiation by a lethal dose of 9.4 Gy. 100 % of anima
Externí odkaz:
https://doaj.org/article/785a47b5e27645359947c5f4ed081264
Publikováno v:
Protein & Cell, Vol 11, Iss 5, Pp 352-365 (2020)
Abstract With its high efficiency for site-specific genome editing and easy manipulation, the clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR associated protein 9 (CAS9) system has become the most widely used gene editing t
Externí odkaz:
https://doaj.org/article/82c631e4cef14b0d9535b7ce8deb7d88
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical information concerning t
Externí odkaz:
https://doaj.org/article/043c9c61b7184bf08508b27b64fd45d4
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101169- (2021)
Etoposide is a semi-synthetic glycoside derivative of podophyllotoxin, also known as VP-16. It is a widely used anticancer medicine in clinics. Unfortunately, high doses or long-term etoposide treatment can induce therapy-related leukemia. The mechan
Externí odkaz:
https://doaj.org/article/252664a45c2245898788140590167781