Zobrazeno 1 - 10
of 4 772
pro vyhledávání: '"double-stranded DNA"'
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 1115-1120 (2024)
The T cell immunoglobulin domain and mucin domain-containing molecule-3 (TIM-3), an inhibitory checkpoint receptor, has been identified as a crucial regulator of cellular immune responses. TIM-3 has been discovered as a receptor involved in the negat
Externí odkaz:
https://doaj.org/article/15dbd7e19f9e4b9fa1a0e5151a391f90
Autor:
Ling-Jie Li, Xiao-Ying Sun, Ya-Ru Huang, Shuai Lu, Yu-Ming Xu, Jing Yang, Xi-Xiu Xie, Jie Zhu, Xiao-Yun Niu, Dan Wang, Shi-Yu Liang, Xiao-Yu Du, Sheng-Jie Hou, Xiao-Lin Yu, Rui-Tian Liu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Deoxyribonuclease 2 (DNase II) plays a key role in clearing cytoplasmic double-stranded DNA (dsDNA). Deficiency of DNase II leads to DNA accumulation in the cytoplasm. Persistent dsDNA in neurons is an early pathological hallmark
Externí odkaz:
https://doaj.org/article/7a9b0bec679c43d4b8d1202c43f3c6dc
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Toxoplasma gondii is a globally occurring apicomplexan parasite that infects humans and animals. Globally, different typical and atypical haplotypes of T. gondii induce varying pathologies in hosts. As an obligate intracellular protozoon, T. gondii w
Externí odkaz:
https://doaj.org/article/4447c5d391d142b7a9194b2e0908e0bb
Autor:
E.A. Potter, E.V. Dolgova, A.S. Proskurina, V.S. Ruzanova, Y.R. Efremov, S.S. Kirikovich, S.G. Oshikhmina, A.L. Mamaev, O.S. Taranov, A.S. Bryukhovetskiy, L.U. Grivtsova, N.A. Kolchanov, A.A. Ostanin, E.R. Chernykh, S.S. Bogachev
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 57 (2024)
Immature hematopoietic progenitors are a constant source for renewal of hemocyte populations and the basic component of the tissue and cell repair apparatus. A unique property of these cells of internalizing extracellular double-stranded DNA has been
Externí odkaz:
https://doaj.org/article/eb89ae519ec54e9bb9db37c989f1b2a4
Autor:
Yifan Sun, Miao Li, Xiaoshan Zhang, Dongjie Xu, Jie Wu, Xinrui Gu, Adeel Khan, Han Shen, Zhiyang Li
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Small extracellular vesicles (sEVs) have great potential as new biomarkers in liquid biopsy. However, due to the limitations of sEVs extraction and component analysis procedures, further clinical applications of sEVs are hampered.
Externí odkaz:
https://doaj.org/article/3a88710dbc1c47d18695dc2567fbe56e
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 5, Pp 799-807 (2023)
Monkeypox virus (MPXV) was confirmed in May 2022 and designated a global health emergency by WHO in July 2022. MPX virions are big, enclosed, brick-shaped, and contain a linear, double-stranded DNA genome as well as enzymes. MPXV particles bind to th
Externí odkaz:
https://doaj.org/article/63b23e1a81504a4c8a3ef6528630f23d
Autor:
Claus-Juergen Bauer, Pantelis Karakostas, Nadine Weber, Charlotte Behning, Birgit Stoffel-Wagner, Peter Brossart, Ramona Dolscheid-Pommerich, Valentin Sebastian Schäfer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveElevated double-stranded DNA (dsDNA) antibody levels in blood serum are considered a disease-specific marker in systemic lupus erythematosus (SLE), correlate with disease activity and the incidence of lupus nephritis, and can be detected in
Externí odkaz:
https://doaj.org/article/384076a064d8415f89d7a1c81a0d06dc
Autor:
Chuqing Sun, Jingchao Chen, Menglu Jin, Xueyang Zhao, Yun Li, Yanqi Dong, Na Gao, Zhi Liu, Peer Bork, Xing‐Ming Zhao, Wei‐Hua Chen
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract DNA methylation plays a crucial role in the survival of bacteriophages (phages), yet the understanding of their genome methylation remains limited. In this study, DNA methylation patterns are analyzed in 8848 metagenome‐assembled high‐qu
Externí odkaz:
https://doaj.org/article/858c8eab8d8047b4a44ea6a4f0c4da7d
Publikováno v:
Sudan Journal of Medical Sciences, Vol 17, Iss 4, Pp 556-564 (2022)
Abstract A 53-year-old female presented with itchiness in her back. She has a 5 years history of tightness of the skin on her face, neck, and torso bilaterally. She did not have other symptoms suggestive of systemic sclerosis (scleroderma), and her r
Externí odkaz:
https://doaj.org/article/06dc2f2c5ad54e2293cfcfabf895b2e6
Publikováno v:
African Journal of Laboratory Medicine, Vol 12, Iss 1, Pp e1-e7 (2023)
Background: Autoantibodies are vital biomarkers for the diagnosis, assessment and prognostic determination of various autoimmune disorders. Objective: This study aimed to evaluate the performance of the two AtheNA Multi-Lyte® systems for the detect
Externí odkaz:
https://doaj.org/article/544a0f31c4824bfb9e7da1ccef40899d