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Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19.

Autor: Queiroz MAF; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Santiago AM; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Virology, Evandro Chagas Institute, Department of Science, Technology, Innovation and Strategic Health Inputs, Ministry of Health of Brazil, Ananindeua, Brazil., Brito WRDS; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Pereira KAS; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., de Brito WB; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Virology, Evandro Chagas Institute, Department of Science, Technology, Innovation and Strategic Health Inputs, Ministry of Health of Brazil, Ananindeua, Brazil., Torres MKDS; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Lopes JDC; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Dos Santos EF; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., da Costa FP; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., de Sarges KML; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Cantanhede MHD; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., de Brito MTFM; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., da Silva ALS; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Leite MM; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Viana MNDSA; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Rodrigues FBB; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., da Silva R; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Viana GMR; Laboratory of Basic Research in Malaria, Parasitology Section, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Brazil., Chaves TDSS; Laboratory of Basic Research in Malaria, Parasitology Section, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Brazil.; School of Medicine, Institute of Medical Sciences, Federal University of Pará, Pará, Brazil., Veríssimo AOL; Belém Adventist Hospital, Belém, Belém, Brazil., Carvalho MDS; Belém Adventist Hospital, Belém, Belém, Brazil., Henriques DF; Laboratory of Immunology, Section of Virology, Instituto Evandro Chagas, Health and Environment Arbovirology and Hemorrhagic Fevers Section, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ananindeua, Brazil., Dos Santos CP; Laboratory of Immunology, Section of Virology, Instituto Evandro Chagas, Health and Environment Arbovirology and Hemorrhagic Fevers Section, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ananindeua, Brazil., Nunes JAL; Laboratory of Immunology, Section of Virology, Instituto Evandro Chagas, Health and Environment Surveillance Secretariat, Brazilian Ministry of Health, Brazilian Ministry of Health, Ananindeua, Brazil., Costa IB; Graduate Program in Virology, Evandro Chagas Institute, Department of Science, Technology, Innovation and Strategic Health Inputs, Ministry of Health of Brazil, Ananindeua, Brazil.; Laboratory of Immunology, Section of Virology, Instituto Evandro Chagas, Health and Environment Surveillance Secretariat, Brazilian Ministry of Health, Brazilian Ministry of Health, Ananindeua, Brazil., Amoras EDSG; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Lima SS; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Cayres-Vallinoto IMV; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil., Brasil-Costa I; Graduate Program in Virology, Evandro Chagas Institute, Department of Science, Technology, Innovation and Strategic Health Inputs, Ministry of Health of Brazil, Ananindeua, Brazil.; Laboratory of Immunology, Section of Virology, Instituto Evandro Chagas, Health and Environment Surveillance Secretariat, Brazilian Ministry of Health, Brazilian Ministry of Health, Ananindeua, Brazil., Quaresma JAS; Center of Biological and Health Sciences, University of the State of Pará, Belém, Brazil., Falcão LFM; Center of Biological and Health Sciences, University of the State of Pará, Belém, Brazil., Dos Santos EJM; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Laboratory of Genetics of Complex Diseases, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil., Vallinoto ACR; Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.; Graduate Program in Biology of Infectious and Parasitic Agents, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, Brazil.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Apr 17; Vol. 14, pp. 1151058. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).