Zobrazeno 1 - 10
of 781
pro vyhledávání: '"docking simulations"'
Autor:
Taehoon Oh, Sunin Jung, Seon Min Oh, Mi Hyeon Park, Hyoung-Geun Kim, Su-Yeon Lee, Sung-Kyun Ko, Hyung Won Ryu
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-9 (2024)
Abstract This study focused on identifying and characterizing 1,3-diphenylpropane derivatives from flavonoids that inhibit human indoleamine 2,3-dioxygenase 1 (hIDO1) enzymes, which play a role in immune regulation and are associated with various dis
Externí odkaz:
https://doaj.org/article/4164bce1073a434e9a531f2c1ac4b150
Publikováno v:
Veterinary World, Vol 17, Iss 6, Pp 1413-1422 (2024)
Background and Aim: Staphylococcus aureus, with its diverse virulence factors and immune response evasion mechanisms, presents a formidable challenge as an opportunistic pathogen. Developing an effective vaccine against S. aureus has proven elusive d
Externí odkaz:
https://doaj.org/article/e60d1dc0364e417a8d118f00d8bc7a31
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract COVID-19 is a global pandemic that caused a dramatic loss of human life worldwide, leading to accelerated research for antiviral drug discovery. Herbal medicine is one of the most commonly used alternative medicine for the prevention and tre
Externí odkaz:
https://doaj.org/article/744fb6452727451bb7412e630701d3c6
Autor:
Saudatu C. Ja'afaru, MChem, Adamu Uzairu, PhD, Anshuman Chandra, PhD, Muhammed S. Sallau, PhD, George I. Ndukwe, PhD, Muhammad T. Ibrahim, PhD, Imteyaz Qamar, PhD
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 2, Pp 429-446 (2024)
الملخص: أهداف البحث: داء البلهارسيات هو مرض استوائي مهمل وسبب رئيسي للوفيات في المناطق المتضررة. في الوقت الحاضر، لا يوجد لقاح عملي لمكاف
Externí odkaz:
https://doaj.org/article/7a95246f4a294a2682de539921d2550b
Autor:
Zahraa S. Al-Garawi, Ahmad H. Ismail, Duaa H. Hillo, Füreya Elif Öztürkkan, Hacali Necefoğlu, Gehad G. Mohamed, Abanoub Mosaad Abdallah
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract A comprehensive investigation into the green synthesis of metal oxide nanoparticles (NPs) has garnered significant attention due to its commendable reliability, sustainability, and environmentally friendly attributes. Green synthesis methods
Externí odkaz:
https://doaj.org/article/54733608da314fa09a1c9ef5ea2bf76e
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 192-202 (2023)
Molecular docking of a large set of thiosemicarbazide-based ligands resulted in obtaining compounds that inhibited both human DNA topoisomerase IIα and indoleamine-2,3-dioxygenase-1 (IDO1). To the best of our knowledge, these compounds are the first
Externí odkaz:
https://doaj.org/article/95c6df3aff69450fa3d3979b9a14a22f
Publikováno v:
Molecules, Vol 29, Iss 16, p 3824 (2024)
Cilostazol is a phosphodiesterase III inhibitor characterized by poor solubility. This limitation can be overcome by using a drug carrier capable of delivering the drug to the target site. Cyclodextrins are essential as drug carriers because of their
Externí odkaz:
https://doaj.org/article/8a095a73c76543e68a3935ceaa0d1703
Autor:
Xiao-Qin He, Hai-Dan Zou, Yi Liu, Xue-Jiao Chen, Atanas G. Atanasov, Xiao-Li Wang, Yu Xia, Siew Bee Ng, Maima Matin, Ding-Tao Wu, Hong-Yan Liu, Ren-You Gan
Publikováno v:
Nutrients, Vol 16, Iss 15, p 2566 (2024)
Researchers are increasingly interested in discovering new pancreatic lipase inhibitors as anti-obesity ingredients. Medicine-and-food homology plants contain a diverse set of natural bioactive compounds with promising development potential. This stu
Externí odkaz:
https://doaj.org/article/eec37415a71c4be693244f0f19db10dc
Autor:
Alfonso Trezza, Roberta Barletta, Michela Geminiani, Luisa Frusciante, Tommaso Olmastroni, Filomena Sannio, Jean-Denis Docquier, Annalisa Santucci
Publikováno v:
Applied Sciences, Vol 14, Iss 15, p 6552 (2024)
Currently, one-third of global food production, accounting for 1.3 billions tons, goes wasted due to major humanitarian and environmental challenges. In such a scenario, the circular bioeconomy model stands as an innovative solution by promoting sust
Externí odkaz:
https://doaj.org/article/ef2030acb0dd4507bba86b2af38f3da1
Publikováno v:
BioTechnologia, Vol 104, Iss 2, Pp 121-136 (2023)
In cyanobacteria, carbonic anhydrase (zinc metalloenzyme) is a major enzyme that converts CO 2 to HCO 3- main¬taining the carbon concentration around the vicinity of RuBisCo, leading to cyanobacterial biomass generation. Anthropogenic activities, di
Externí odkaz:
https://doaj.org/article/0c9f4e1035ad4affad81a316b82f3513