Comparative genome analysis of a multidrug-resistant Pseudomonas aeruginosa sequence type 277 clone that harbours two copies of the blaSPM-1 gene and multiple single nucleotide polymorphisms in other resistance-associated genes

Autor: Sousa H, da Silva Fab, Carvalho-Assef Apd, Rodolpho Mattos Albano, dos Santos Mt, Hermes Senger, Fernando Medeiros Filho, do Nascimento Apb

Pseudomonas aeruginosa is one of the most common pathogens related to healthcare-associated infections. The Brazilian isolate, named CCBH4851, is a multidrug-resistant clone belonging to the sequence type 277. The antimicrobial resistance mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1985f01a3ebcdc0a1d90de92874d8524

Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts.

Autor: Gonzalez Dias Carvalho PC; Oxford Vaccine Group, University of Oxford, Oxford, United Kingdom.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Dominguez Crespo Hirata T; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Mano Alves LY; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Moscardini IF; Microbiotec Srl, Siena, Italy., do Nascimento APB; Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Costa-Martins AG; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Artificial Intelligence and Analytics Department, Institute for Technological Research, São Paulo, Brazil., Sorgi S; Laboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, Siena, Italy., Harandi AM; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Vaccine Evaluation Center, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada., Ferreira DM; Oxford Vaccine Group, University of Oxford, Oxford, United Kingdom.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Vianello E; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Haks MC; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Santoro F; Laboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, Siena, Italy., Martinez-Murillo P; Centre for Vaccinology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Huttner A; Centre for Vaccinology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Infectious Diseases Service, Geneva University Hospitals, Geneva, Switzerland., Siegrist CA; Centre for Vaccinology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Medaglini D; Department of Medical Biotechnologies, University of Siena, Siena, Italy., Nakaya HI; Scientific Platform Pasteur-University of São Paulo, São Paulo, Brazil.; Hospital Israelita Albert Einstein, São Paulo, Brazil.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Nov 08; Vol. 14, pp. 1259197. Date of Electronic Publication: 2023 Nov 08 (Print Publication: 2023).

A Systematic Strategy to Find Potential Therapeutic Targets for Pseudomonas aeruginosa Using Integrated Computational Models.

Autor: Medeiros Filho F; Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., do Nascimento APB; Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., Costa MOCE; Laboratório Nacional de Computação Científica, Petrópolis, Brazil., Merigueti TC; Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., de Menezes MA; Instituto de Física, Universidade Federal Fluminense, Niterói, Brazil., Nicolás MF; Laboratório Nacional de Computação Científica, Petrópolis, Brazil., Dos Santos MT; Laboratório Nacional de Computação Científica, Petrópolis, Brazil., Carvalho-Assef APD; Laboratório de Pesquisa Em Infecção Hospitalar, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., da Silva FAB; Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

Publikováno v: Frontiers in molecular biosciences [Front Mol Biosci] 2021 Sep 20; Vol. 8, pp. 728129. Date of Electronic Publication: 2021 Sep 20 (Print Publication: 2021).

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa.

Autor: Medeiros Filho F; Fundação Oswaldo Cruz, Programa de Computação Científica, Rio de Janeiro, RJ, Brasil., do Nascimento APB; Fundação Oswaldo Cruz, Programa de Computação Científica, Rio de Janeiro, RJ, Brasil., Dos Santos MT; Laboratório Nacional de Computação Científica, Petrópolis, RJ, Brasil., Carvalho-Assef APD; Fundação Oswaldo Cruz, Instituto Oswaldo Cruz, Laboratório de Pesquisa em Infecção Hospitalar, Rio de Janeiro, RJ, Brasil., da Silva FAB; Fundação Oswaldo Cruz, Programa de Computação Científica, Rio de Janeiro, RJ, Brasil.

Publikováno v: Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2019; Vol. 114, pp. e190105. Date of Electronic Publication: 2019 Aug 05.