Dna Polymerases: Discovery, Characterization And Functions In Cellular Dna Transactions

Autor: Ulrich Hubscher, Giovanni Maga, Giuseppe Villani, Silvio Spadari

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in

Systematic analysis of DNA polymerases as therapeutic targets in pan-cancers.

Autor: ZHENHUA LI¹, HUILAI LV¹, FAN ZHANG¹, ZIMING ZHU², QIANG GUO³, MINGBO WANG¹, CHAO HUANG¹, LIJUAN CHEN⁴, WENPAN ZHANG⁴, YUN LI⁵ liyun28@mail.sysu.edu.cn, ZIQIANG TIAN¹ tianzq1026@163.com

Publikováno v: Biocell. 2024, Vol. 48 Issue 1, p123-138. 16p.

DNA polymerases in precise and predictable CRISPR/Cas9-mediated chromosomal rearrangements.

Autor: Mehryar, Mohammadreza M.^1,2 (AUTHOR), Shi, Xin^1,2 (AUTHOR), Li, Jingwei^1,2 (AUTHOR), Wu, Qiang^1,2 (AUTHOR) qiangwu@sjtu.edu.cn

Publikováno v: BMC Biology. 12/8/2023, Vol. 21 Issue 1, p1-16. 16p.

Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families.

Autor: Weber, Christine A. M.¹ (AUTHOR), Krönke, Nicole² (AUTHOR), Volk, Valery² (AUTHOR), Auber, Bernd¹ (AUTHOR), Förster, Alisa¹ (AUTHOR), Trost, Detlef³ (AUTHOR), Geffers, Robert⁴ (AUTHOR), Esmaeilzadeh, Majid⁵ (AUTHOR), Lalk, Michael⁶ (AUTHOR), Nabavi, Arya⁶ (AUTHOR), Samii, Amir⁷ (AUTHOR), Krauss, Joachim K.⁵ (AUTHOR), Feuerhake, Friedrich^2,8 (AUTHOR), Hartmann, Christian² (AUTHOR), Wiese, Bettina^5,9 (AUTHOR), Brand, Frank¹ (AUTHOR), Weber, Ruthild G.¹ (AUTHOR) Weber.Ruthild@mh-hannover.de

Publikováno v: Acta Neuropathologica Communications. 11/21/2023, Vol. 11 Issue 1, p1-20. 20p.

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