Zobrazeno 1 - 10
of 38
pro vyhledávání: '"dna topoisomerase (atp hydrolysing)"'
Autor:
Yavuz Ergun, Serdar Durdagi, Zeki Topcu, Á. Kulmány, M. Zaka, Kader Sahin, István Zupkó, Sevil Zencir, M. Kuskucu, V. Akyildiz, Hilmi Orhan
The compounds reducing tumor cell viability and disrupting DNA topoisomerase reactions have been widely used in anticancer drug development. Ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole) is a potent intercalating agent that interferes with nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2de3987d1a58efe767ceaedadbde0b
https://avesis.deu.edu.tr/publication/details/9e8b704c-2c4e-4d59-922b-200d244321d7/oai
https://avesis.deu.edu.tr/publication/details/9e8b704c-2c4e-4d59-922b-200d244321d7/oai
Autor:
Joel-Sean Hsu, Yavuz Ergun, Sevil Zencir, Zeki Topcu, Guan-Ling Chou, Meng-Hsun Hsieh, Shu-Chun Teng, Tsai-Kun Li
Background DNA topoisomerase and telomerase enzymes are popular targets of several anti-tumor drugs. Smooth proceeding of telomeric recombination requires Topoisomerase II (Top2), which is involved in telomere-telomere recombination through functioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b048c1d0e38533aa90570de7e4a71
https://aperta.ulakbim.gov.tr/record/5665
https://aperta.ulakbim.gov.tr/record/5665
The aims of this study were to determine the prevalence and phylogenetic relationship of motile Aeromonas spp. that might be pathogenic species for rainbow trout in infected/mix infection cases (based upon different outbreaks on fish farms). A total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d637d4d6e21797709444b951c89db7
https://avesis.erciyes.edu.tr/publication/details/d37e00e5-2958-4c17-9b96-0f17e7ba252c/oai
https://avesis.erciyes.edu.tr/publication/details/d37e00e5-2958-4c17-9b96-0f17e7ba252c/oai
Aim: Over the last decade, Citrobacter species have been responsible for infections in fish and many species and also new Citrobacter species have been identified. In this study, molecular identifications and the phenotypic and genotypic antimicrobia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c1250b310bf74e5ee56977061c8130
http://hdl.handle.net/11452/29300
http://hdl.handle.net/11452/29300
Publikováno v:
Bioorganic Chemistry
From a medical point of view lot of existing antibiotics became unusable because microbial gained strong antibiotic resistance. The combination of two compounds in one core may lead to kill such type of pathogens. Herein, we developed pyranopyrazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d67f7ca4a79db5234307d1e5fccfb1
https://doi.org/10.1016/j.bioorg.2020.103908
https://doi.org/10.1016/j.bioorg.2020.103908
Autor:
Yaidelys Iglesias-Torrens, Anna Maria Dionisi, Alessandra Carattoli, Aurora García-Fernández, Sergio Arena, Ida Luzzi
Publikováno v:
Frontiers in Microbiology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Frontiers in Microbiology, Vol 9 (2018)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Frontiers in Microbiology, Vol 9 (2018)
Campylobacter spp. is one of the main cause of bacterial gastroenteritis in the world. The increase of antibiotic resistance in this species is a threat to public health. A Campylobacter spp. surveillance study was performed in Italy in the 2013–20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af24bf706513b85069740400ea848cbd
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14030
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14030
Publikováno v:
Chemical research in toxicology. 29(3)
WOS: 000372677900019
PubMed ID: 26894873
Two metabolites from the ascomycete fungus Septofusidium berolinense were recently identified as having antineoplastic activity [Ekiz et al. (2015) J. Antibiot., DOI: 10.1038/ja.2015.84]. However, th
PubMed ID: 26894873
Two metabolites from the ascomycete fungus Septofusidium berolinense were recently identified as having antineoplastic activity [Ekiz et al. (2015) J. Antibiot., DOI: 10.1038/ja.2015.84]. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dc05536d096bbca50247ac3c97254d
https://pubmed.ncbi.nlm.nih.gov/26894873
https://pubmed.ncbi.nlm.nih.gov/26894873
WOS: 000371344600033
PubMed ID: 26906637
Ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole) is an antineoplastic agent that intercalates into DNA and alters topoisomerase II activity. Unfortunately, this compound displays a number of adv
PubMed ID: 26906637
Ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole) is an antineoplastic agent that intercalates into DNA and alters topoisomerase II activity. Unfortunately, this compound displays a number of adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36a1f6b859fdb0d1309427d07498061
https://hdl.handle.net/11454/52955
https://hdl.handle.net/11454/52955
Autor:
Istanbullu, Huseyin, Zencir, Sevil, Berenyi, Agnes, Canturk Kilickaya, Pakize, Zupko, Istvan, Erciyas, Ercin, Topcu, Zeki
WOS: 000361222900001
Majority of anti-cancer drugs were shown to exert their activities by interfering with DNA topoisomerase reactions. Since the identification of Camptothecin as the topoisomerase I targeting compound, these enzymes are widely
Majority of anti-cancer drugs were shown to exert their activities by interfering with DNA topoisomerase reactions. Since the identification of Camptothecin as the topoisomerase I targeting compound, these enzymes are widely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf8f61148d6fb50786b564af460f544
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/10481
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/10481
Publikováno v:
BMC Structural Biology
BMC Structural Biology, Vol 11, Iss 1, p 47 (2011)
BMC Structural Biology, Vol 11, Iss 1, p 47 (2011)
Background Fluoroquinolone resistance is a serious threat in the battle against the treatment of multi drug resistant tuberculosis (MDR-TB) and extensively drug resistant tuberculosis (XDR-TB). Fluoroquinolone resistant isolates from India had shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9617982de6d62f0227ed23cf363e4c
https://doi.org/10.1186/1472-6807-11-47
https://doi.org/10.1186/1472-6807-11-47