Zobrazeno 1 - 10
of 2 909
pro vyhledávání: '"dkk1"'
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 73-82 (2024)
Neuroblastomas are pediatric tumors arising from undifferentiated cells of neural crest origin with stem cell-like characteristics. Dysregulation of Wnt/β-catenin signaling has been shown to be linked to the development of various tumors. Activated
Externí odkaz:
https://doaj.org/article/306a87f63d1a4d5cb607bb23c9bc73ea
Autor:
Hong-Xiang Shi, Hang-Tian Tao, Jin-Jin He, Feng-Yi Zhu, Cui-Qing Xie, Yu-Na Cheng, Li-Li Hou, Hua Sun, Chang-Jiang Qin, Dong Fang, Song-Qiang Xie
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-7 (2024)
Abstract Chemotherapy in combination with immunotherapy has gradually shown substantial promise to increase T cell infiltration and antitumor efficacy. However, paclitaxel in combination with immune checkpoint inhibitor targeting PD-1/PD-L1 was only
Externí odkaz:
https://doaj.org/article/60a78acb20c24ca5828e7fab1fc4e372
Autor:
Zhanqin Zhang, Jianguo Hu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Introduction Intrauterine adhesions (IUA) manifest as endometrial fibrosis, often causing infertility or recurrent miscarriage; however, their pathogenesis remains unclear. Objectives This study assessed the role of Dickkopf WNT signaling pa
Externí odkaz:
https://doaj.org/article/1305bc36947d4a0fb7d0d5bf52167315
Autor:
Lan Chen, Caixia Kong
Publikováno v:
Gynecological Endocrinology, Vol 40, Iss 1 (2024)
Background Polycystic ovarian syndrome (PCOS) is a prevalent metabolic and endocrine condition in females of reproductive age. This work was to discover the underlying role of Dickkopf 1 (DKK1) and its putative regulating mechanism in P COS.Methods M
Externí odkaz:
https://doaj.org/article/5ef9ed74d5e847dfaabe9bd014a0d2c2
Autor:
Yeke Wu, Bin Li, Disi Deng, Hongling Zhou, Min Liu, Huangping Ai, Yilin Xin, Weihan Hua, Lixing Zhao, Li Li
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
AbstractMicroRNA (miRNA) plays a regulatory role in periodontitis. This study aimed to explore whether miR-29a could affect lipopolysaccharides (LPSs)-induced injury in human gingival fibroblasts (HGFs) through the competitive endogenous RNAs (ceRNA)
Externí odkaz:
https://doaj.org/article/a73a0ce5fec241dcb97dbb252ecd70f1
Autor:
Jiayi Song, Weirong Chang, Yujie Wang, Peng Gao, Jie Zhang, Zhipan Xiao, Fangyu An, Chunlu Yan
Publikováno v:
Biomolecules & Biomedicine (2024)
The Wnt signaling pathway is one of the most important and critical signaling pathways for maintaining cellular functions, such as cell proliferation and differentiation. Increasing evidence substantiates that the Wnt signaling pathway also plays a s
Externí odkaz:
https://doaj.org/article/5935a9de68bb43c19aed5fe9e47e44a2
Autor:
Jih-Yang Ko, Feng-Sheng Wang, Wei-Shiung Lian, Fu-Shine Yang, Jeng-Wei Chen, Po-Hua Huang, Chin-Yi Liao, Shu-Jui Kuo
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Background The current treatment of osteogenesis imperfecta (OI) is imperfect. Our study thus delves into the potential of using Dickkopf-1 antisense (DKK1-AS) to treat OI. Methods We analysed serum DKK1 levels and their correlation with lum
Externí odkaz:
https://doaj.org/article/276d3cc336804daa9c83b2dba42ea14d
Akademický článek
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Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Wnt signaling is critically involved in fracture healing. Existing data predominantly relies on rodent models. Here, we explored local and circulating Dickkopf-1 (DKK1) levels in patients with respect to fracture healing and explore its asso
Externí odkaz:
https://doaj.org/article/82e37a7e4baf4d878fd93f5f25b05214
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the induced pluripotent stem cells (IPS) in modulating the expression of the card
Externí odkaz:
https://doaj.org/article/f1f72a81225a46b09284548079102194