Zobrazeno 1 - 10
of 2 936
pro vyhledávání: '"disease modifying therapy"'
Autor:
Ferrán Catalá-López, Laura Tejedor-Romero, Jane A. Driver, Brian Hutton, Joan Vicent Sánchez-Ortí, Manuel Ridao, Adolfo Alonso-Arroyo, Patricia Correa-Ghisays, Jaume Forés-Martos, Vicent Balanzá-Martínez, Alfonso Valencia, Inmaculada Cobos, Rafael Tabarés-Seisdedos
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-8 (2024)
Abstract Background The association between cancer and multiple sclerosis has long been investigated. Several studies and reviews have examined the risk of cancer among patients with multiple sclerosis treated with disease-modifying therapies (DMTs)
Externí odkaz:
https://doaj.org/article/54e5cd3b07104a789bf50af816364463
Autor:
Robert Zivadinov, Alexander J. Keenan, Hoa H. Le, Maria Ait-Tihyaty, Kavita Gandhi, Matthew L. Zierhut, Elizabeth M. Salvo-Halloran, Abril Oliva Ramirez, Vivian Vuong, Sumeet Singh, Brian Hutton
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Brain volume loss (BVL) has been identified as a predictor of disability progression in relapsing multiple sclerosis (RMS). As many available disease-modifying treatments (DMTs) have shown an effect on slowing BVL, this is becomin
Externí odkaz:
https://doaj.org/article/97264d5b987049ffa4492a729b163739
Autor:
Kenichiro Sato, Yoshiki Niimi, Ryoko Ihara, Atsushi Iwata, Kazushi Suzuki, Kiyotaka Nemoto, Tetsuaki Arai, Shinji Higashi, Ataru Igarashi, Kensaku Kasuga, Shuichi Awata, Takeshi Iwatsubo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background The approval of lecanemab, an anti-amyloid therapy for Alzheimer’s disease (AD), necessitates addressing healthcare preparedness for disease-modifying treatment (DMT) to ensure appropriate, safe, and sustainable drug administrat
Externí odkaz:
https://doaj.org/article/2081c853d90b4acc8f80efd30040c77a
Autor:
Dominika Stastna, Jiri Drahota, Michal Lauer, Aneta Mazouchova, Ingrid Menkyova, Jana Adamkova, Radek Ampapa, Michal Dufek, Marketa Grunermelova, Pavel Hradilek, Eva Kubala Havrdova, Jan Mares, Alena Martinkova, Zbysek Pavelek, Marek Peterka, Eva Recmanova, Petra Rockova, Ivana Stetkarova, Pavel Stourac, Marta Vachova, Dana Horakova
Publikováno v:
Biomedical Papers, Vol 168, Iss 3, Pp 262-270 (2024)
Aims. Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, we describe the actual da
Externí odkaz:
https://doaj.org/article/031942c91d96488a818590beaafcebd7
Autor:
Bassem Yamout, Raed Alroughani, Jihad Inshasi, Samar Farouk, Fatema Abdulla, Namareq Y. Al-Jarki, Abdulla Alasmi, Sarmad Al Fahad, Jaber Alkhabouri, Khalid Al-Saffar, Beatrice Benedetti, Beatriz Canibano, Dirk Deleu, Ali Hassan, Pournamy Sarathchandran, Ahmed Shatila, Mohammad Abouelnaga, Mona Thakre, Miklos Szolics, Amir Boshra
Publikováno v:
Neurology and Therapy, Vol 13, Iss 5, Pp 1321-1335 (2024)
Abstract Cladribine tablets (CladT), like alemtuzumab, acts as an immune reconstitution therapy. However, CladT is administered orally (alemtuzumab is given by infusion) and without the potential for serious side effects that limit the therapeutic us
Externí odkaz:
https://doaj.org/article/a456e8fecb904caa838b18d50372bc33
Autor:
Hyung-Ik Shin
Publikováno v:
Annals of Rehabilitation Medicine, Vol 48, Iss 4, Pp 229-238 (2024)
The impact of disease-modifying therapy ranges from cure to no impact with a wide range of intermediates. In cases where the intermediate group reaches a plateau after the acquisition of some muscle strength, it is necessary to set a functional level
Externí odkaz:
https://doaj.org/article/d8b44cc293fd4d4aa61de64d585de1b2
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Background: The ability of mesenchymal stromal cells (MSCs) to facilitate regenerative responses in inflamed and injured tissues, coupled with preclinical data suggesting potential to restore defective collagen VII at the dermo-epidermal junction, ha
Externí odkaz:
https://doaj.org/article/efb7b29873f44fc58aad2d306a78a086
Autor:
Enrique Alvarez, Lawrence Steinman, Edward J. Fox, Hans-Peter Hartung, Peiqing Qian, Sibyl Wray, Derrick Robertson, Krzysztof Selmaj, Daniel Wynn, Koby Mok, Yihuan Xu, Karthik Bodhinathan, Hari P. Miskin, Bruce A. C. Cree
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundUblituximab is a novel anti-CD20 monoclonal antibody glycoengineered for enhanced antibody-dependent cellular cytotoxicity. The phase 3 ULTIMATE I and II studies showed significant improvements in annualized relapse rate, total number of ga
Externí odkaz:
https://doaj.org/article/130d74d067b24a7298186ec6d38aa0d2
Publikováno v:
Репродуктивная эндокринология, Iss 72, Pp 60-70 (2024)
Objective of the review: to study the topic of fertility, pregnancy and assisted reproductive technologies (ART) in patients with multiple sclerosis (MS). The analysis of scientific literature in international medical databases was performed. Analysi
Externí odkaz:
https://doaj.org/article/72589e99c52441f19429336f02750703
Autor:
Seyedeh Sadigheh Hamzavi, Rosemina Bahrololoom, Sepideh Saeb, Nahid Heydari Marandi, Marzieh Hosseini, Alimohammad Keshtvarz hesam abadi, Marzieh Jamalidoust
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background For the past three years, the pandemic has had a major effect on global public health, mainly on those with underlying medical conditions, such as people living with Multiple Sclerosis. Vaccination among this group is of great imp
Externí odkaz:
https://doaj.org/article/4ca85b3b60ce471790ed91864595c771