Zobrazeno 1 - 10
of 1 504
pro vyhledávání: '"direct-acting antiviral agents"'
Autor:
Hao Xiong, Jinsheng Guo
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 3, Pp 226-240 (2024)
Hepatitis C viral infections present a significant global health challenge, carrying substantial economic implications. These infections manifest in various clinical forms, including acute and chronic hepatitis, liver cirrhosis, hepatic failure, and
Externí odkaz:
https://doaj.org/article/4b86acf97fe04b97aaf447029b5110f1
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Direct-acting Antiviral Agents (DAAs) influence serum lipids of patients with Hepatitis C virus (HCV). This paper presents an analysis of the relevant literature to investigate the effects of DAAs in treating hepatitis C to achiev
Externí odkaz:
https://doaj.org/article/b0145164cfe4446092398b8bf81737e5
Autor:
Oana Koppandi, Dana Iovănescu, Bogdan Miuțescu, Alexandru Cătălin Motofelea, Oana Maria Jigău, Andreea Iulia Papoi, Călin Burciu, Eyad Gadour, Deiana Vuletici, Eftimie Miuțescu
Publikováno v:
Medicina, Vol 60, Iss 8, p 1295 (2024)
Background and Objectives: Chronic hepatitis C virus (HCV) infection is intricately linked with dysregulation of lipid metabolism. In particular, cholesterol plays a crucial role in HCV replication. Direct-acting antiviral agents (DAAs) therapy has r
Externí odkaz:
https://doaj.org/article/840c5723affe4b08a89dee70859728f1
Publikováno v:
Pathogens, Vol 13, Iss 6, p 508 (2024)
Prior to the Food and Drug Administration approval of ledipaspavir/sofosbuvir (Harvoni®) in 2014, the treatment of hepatitis C was interferon plus or minus ribavirin. This treatment had low cure rates for hepatitis C virus and was teratogenic and th
Externí odkaz:
https://doaj.org/article/d5a3967d420240d29a7217be6fcdc04e
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Chronic hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC). The HCC risk, while decreased compared with active HCV infection, persists in HCV-cured patients by direct-acting antiviral agents (DAA). We previous
Externí odkaz:
https://doaj.org/article/4ebdc79139664e46997b83b5df186132
Autor:
Allah Nawaz, Azhar Manzoor, Saeed Ahmed, Naveed Ahmed, Waseem Abbas, Mushtaq Ahmad Mir, Muhammad Bilal, Alisha Sheikh, Saleem Ahmad, Ishtiaq Jeelani, Takashi Nakagawa
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon
Externí odkaz:
https://doaj.org/article/68349878a3bc49a588b53da8071b88e6
Autor:
Takashi Satoh, Haruki Uojima, Naohisa Wada, Hayato Takiguchi, Mei Kaneko, Marina Nakamura, Natsuki Gonda, Michika Homma, Hisashi Hidaka, Chika Kusano, Ryouichi Horie
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
The pathogenesis of thrombocytopenia in chronic hepatitis C (CHC) conceivably involves autoimmunity; however, the dynamics of autoantibodies and other autoimmune mechanisms remain unclear. In this study, we examined the changes in the frequency of an
Externí odkaz:
https://doaj.org/article/89c876df34b3405fa37910035c4a8761
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Patients infected with Hepatitis C virus (HCV) are recommended to receive treatment with direct-acting antiviral agents (DAAs), which have been certified to obtain a high sustained virological response (SVR). However, little is kn
Externí odkaz:
https://doaj.org/article/d019b94d851442a3a11ac0d9b2367529
Publikováno v:
Journal of the Pakistan Medical Association, Vol 73, Iss 11 (2023)
Objective: To determine the usefulness of Sofosbuvir-Daclatasvir combination in the treatment of hepatitis c virus infection in paediatric cancer. Method: The retrospective study was conducted at the Oncology Department of the National Institute of
Externí odkaz:
https://doaj.org/article/494501816b4e46d3bfb0c6886a71d444
Publikováno v:
Türk Biyokimya Dergisi, Vol 48, Iss 1, Pp 44-50 (2022)
The aim of this study was to investigate the changes in thiol/disulfide balance, pro-fibrotic mediators (transforming growth factor-beta [TGF-β] and periostin) and a potential biomarker for the prediction of HCV-induced HCC (3β-hydroxysterol Δ24-r
Externí odkaz:
https://doaj.org/article/1f2c296c2a594e83a1f896847bf24080