Zobrazeno 1 - 10
of 79
pro vyhledávání: '"direct cardiac reprogramming"'
Autor:
Peisen Huang, Jun Xu, Benjamin Keepers, Yifang Xie, David Near, Yangxi Xu, James Rock Hua, Brian Spurlock, Shea Ricketts, Jiandong Liu, Li Wang, Li Qian
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102390- (2024)
Direct cardiac reprogramming of fibroblasts into induced cardiomyocytes (iCMs) can be achieved by ectopic expression of cardiac transcription factors (TFs) via viral vectors. However, risks like genomic mutations, viral toxicity, and immune response
Externí odkaz:
https://doaj.org/article/c769ac982e584f6f89172252efc78bd4
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 9, p 273 (2024)
Heart disease continues to be one of the most fatal conditions worldwide. This is in part due to the maladaptive remodeling process by which ischemic cardiac tissue is replaced with a fibrotic scar. Direct cardiac reprogramming presents a unique solu
Externí odkaz:
https://doaj.org/article/182e6e01f5274c9e944e530f9b04a4c9
Autor:
Huang, Peisen 1, 2, 3, Xu, Jun 1, 2, 3, Keepers, Benjamin 1, 2, Xie, Yifang 1, 2, Near, David 1, 2, Xu, Yangxi 1, 2, Hua, James Rock 1, Spurlock, Brian 1, 2, Ricketts, Shea 1, 2, Liu, Jiandong 1, 2, Wang, Li 1, 2, ∗, Qian, Li 1, 2, ∗∗
Publikováno v:
In Molecular Therapy - Nucleic Acids November 2024
Publikováno v:
In Journal of Molecular and Cellular Cardiology May 2023 178:1-8
Autor:
Cao, Yiqiu a, b, f, Dong, Zhu a, c, Yang, Dongpeng a, d, Ma, Ximiao a, e, Wang, Xiaowu a, c, f, ∗
Publikováno v:
In Experimental Cell Research 1 September 2022 418(1)
Publikováno v:
In Seminars in Cell and Developmental Biology February 2022 122:44-49
Autor:
Tang, Yawen a, Zhao, Lianzhong b, c, Yu, Xufen d, Zhang, Jianyi a, Qian, Li e, Jin, Jian d, Lu, Rui b, c, Zhou, Yang a, ⁎
Publikováno v:
In Stem Cell Research May 2021 53
Autor:
Hiroyuki Yamakawa, Masaki Ieda
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-10 (2021)
Abstract Japan faces an increasing incidence of heart disease, owing to a shift towards a westernized lifestyle and an aging demographic. In cases where conventional interventions are not appropriate, regenerative medicine offers a promising therapeu
Externí odkaz:
https://doaj.org/article/9351bf92925c46a4a4a16533519f963d
Autor:
Siyuan Ma, Junyu Yan, Lu Chen, Yingqi Zhu, Kaitong Chen, Cankun Zheng, Mengjia Shen, Yulin Liao
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Recent research has suggested that cardiac regeneration may have the widely applicable potential of treating heart failure (HF). A comprehensive understanding of the development status of this field is conducive to its development. Howeve
Externí odkaz:
https://doaj.org/article/783d7a0782bd42c388a50a09367cbf6d
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102365- (2021)
Cardiovascular disease, until now, is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury cannot be reversed and eventually progress into heart failure. In
Externí odkaz:
https://doaj.org/article/684e38437a054f62b735d17e3d6c583b