Zobrazeno 1 - 10
of 28
pro vyhledávání: '"diphenylmethylpiperazine"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Cell wall deficient “L- form” bacteria are of growing medical interest as a possible source of recurrent or persistent infection, largely because of their complete resistance to cell wall active antibiotics such as β-lactams. Antibiotics that sp
Externí odkaz:
https://doaj.org/article/52debd27b8e94e4e925e59f029240a57
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Richard James Lewis, Aijun Yang, Jonathan B. Baell, Kellie L. Tuck, Charlotte Elisabet Tranberg, Jeffrey R. McArthur, Peter J. Duggan, Irina Vetter
Publikováno v:
Marine Drugs
Marine Drugs, Vol 10, Iss 10, Pp 2349-2368 (2012)
Marine Drugs; Volume 10; Issue 10; Pages: 2349-2368
Marine Drugs, Vol 10, Iss 10, Pp 2349-2368 (2012)
Marine Drugs; Volume 10; Issue 10; Pages: 2349-2368
The neuronal voltage-gated N-type calcium channel (Ca(v)2.2) is a validated target for the treatment of neuropathic pain. A small library of anthranilamide-derived ω-Conotoxin GVIA mimetics bearing the diphenylmethylpiperazine moiety were prepared a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87310ffedd3327ad12e318fd7a6f3943
http://europepmc.org/articles/PMC3497028
http://europepmc.org/articles/PMC3497028
Publikováno v:
Medicinal Chemistry Research. 21:124-132
A series of novel (R)(-)-1-[(4-chlorophenyl)phenylmethyl]piperazine derivatives were designed, synthesized, and tested for in vivo anti-allergic activities. Most of these derivatives exhibited significant effects on both allergic asthma and allergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::060e345e639cce310eca90c2eafea8c8
https://doi.org/10.1007/s00044-010-9512-1
https://doi.org/10.1007/s00044-010-9512-1
Autor:
Daniel J. Canney, Richie R. Bhandare
Publikováno v:
Medicinal Chemistry Research. 20:558-565
Lead lactone-based ligands with modest affinity for muscarinic receptors were modified based on structure–activity relationship data in the literature to provide a new series of 5-substituted 4,5-dihydro-2(3H)-furanones. The modifications included
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6132f1d1ce9d7df0f2a9e2e6216bcc0
https://doi.org/10.1007/s00044-010-9349-7
https://doi.org/10.1007/s00044-010-9349-7
Autor:
Félix Sánchez-Alonso, Juan-Julio Bonet, Antonio Alivert, Francesc Canals, Vicente Gómez-Parra
Publikováno v:
Archiv der Pharmazie. 324:559-561
The synthesis and preliminary assays as hypocholesterolemic agents of five N-diphenylmethylpiperazines are described. The evaluations were carried out in hypercholesterolemic mice and two of these compounds were more effective than bezafibrate in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9d3c915c7ee0e0afd5da47f96cad9f
https://doi.org/10.1002/ardp.2503240907
https://doi.org/10.1002/ardp.2503240907
Autor:
Richie R. Bhandare, Daniel J. Canney
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 10(4)
Previous structure-activity relationship studies involving a series of lactone-based muscarinic ligands identified a lead compound containing a diphenylmethylpiperazine moiety (4; IC50 = 340 nM). The purpose of the present work is to investigate 1,3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e33ba54d846108e805883c023d9481
https://pubmed.ncbi.nlm.nih.gov/24021160
https://pubmed.ncbi.nlm.nih.gov/24021160
Autor:
Silvia N. Calderon
Publikováno v:
Topics in Current Chemistry ISBN: 9783642181061
The discovery of the selective delta (delta) opioid agonists SNC 80 and BW373U86, which possess a diarylmethylpiperazine structure unique among opioids, represented a major advance in the field of delta-opioid ligands. Extensive research has recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c159258c2e95d45b936dbb0ecc90828a
https://doi.org/10.1007/128_2010_83
https://doi.org/10.1007/128_2010_83
Publikováno v:
E-Journal of Chemistry, Vol 6, Iss S1, Pp S473-S479 (2009)
A series of amino acid conjugated diphenylmethylpiperazine derivatives were synthesized by coupling diphenylmethylpiperazine with different Boc-amino acids using EDCI/HOBt as coupling agent and NMM as base. The synthesized compounds were characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94c916e2f9844ba68f6b19d83bc0a59
https://doaj.org/article/67ccd9c1a05148ce9c17aa8c1f4f63ba
https://doaj.org/article/67ccd9c1a05148ce9c17aa8c1f4f63ba
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.