Zobrazeno 1 - 10
of 66
pro vyhledávání: '"diffracted X-ray tracking"'
Autor:
Daisuke Sasaki, Tatsuya Arai, Yue Yang, Masahiro Kuramochi, Wakako Furuyama, Asuka Nanbo, Hiroshi Sekiguchi, Nobuhiro Morone, Kazuhiro Mio, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101712- (2024)
Single-molecule intramolecular dynamics were successfully measured for three variants of SARS-CoV-2 spike protein, alpha: B.1.1.7, delta: B.1.617, and omicron: B.1.1.529, with a time resolution of 100 μs using X-rays. The results were then compared
Externí odkaz:
https://doaj.org/article/e11640f8ec6b41749adcc6e2be830094
Autor:
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Mayui Sugiura, Kayoko Kawaguchi, Kazutaka Araki, Keizaburo Taninaka, Masaki Sakaguchi, Shunsuke Nozawa, Tatsuya Arai, Yuji C. Sasaki
Publikováno v:
Membranes, Vol 14, Iss 4, p 75 (2024)
Protein dynamics play important roles in biological functions, which accompany allosteric structure changes. Diffracted X-ray blinking (DXB) uses monochromatic X-rays and nanocrystal probes. The intramolecular motion of target proteins is analyzed fr
Externí odkaz:
https://doaj.org/article/4338b407ac3f4b2b83dc2cf75de5ef2a
Autor:
Koichiro Saito, Kouhei Ichiyanagi, Ryo Fukaya, Rie Haruki, Shunsuke Nozawa, Daisuke Sasaki, Tatsuya Arai, Yuji C. Sasaki, Keegan McGehee, Makoto Saikawa, Minghao Gao, Zhichao Wei, Dennis Kwaria, Yasuo Norikane
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17462 (2023)
The photoinduced crawling motion of crystals is a continuous motion that azobenzene molecular crystals exhibit under light irradiation. Such motion enables object manipulation at the microscale with a simple setup of fixed LED light sources. Transpor
Externí odkaz:
https://doaj.org/article/d8965e1cd53c47fd8731b74e42a4c4fe
Autor:
Tsutomu Yamane, Takahiro Nakayama, Toru Ekimoto, Masao Inoue, Keigo Ikezaki, Hiroshi Sekiguchi, Masahiro Kuramochi, Yasuo Terao, Ken Judai, Minoru Saito, Mitsunori Ikeguchi, Yuji C. Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15423 (2023)
Tubulin has been recently reported to form a large family consisting of various gene isoforms; however, the differences in the molecular features of tubulin dimers composed of a combination of these isoforms remain unknown. Therefore, we attempted to
Externí odkaz:
https://doaj.org/article/736c0348e64e4bc4b0245f0be318acec
Autor:
Yuji C. Sasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14829 (2023)
In 1998, the diffracted X-ray tracking (DXT) method pioneered the attainment of molecular dynamics measurements within individual molecules. This breakthrough revolutionized the field by enabling unprecedented insights into the complex workings of mo
Externí odkaz:
https://doaj.org/article/9ca31fe988eb4c37bfa57bb2be87a708
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14850 (2023)
The CCT/TRiC complex is a type II chaperonin that undergoes ATP-driven conformational changes during its functional cycle. Structural studies have provided valuable insights into the mechanism of this process, but real-time dynamics analyses of mamma
Externí odkaz:
https://doaj.org/article/bc7387d2a219421da3094e9f1a9048e2
Akademický článek
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Autor:
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Tatsuya Arai, Mayui Sugiura, Shoko Fujimura, Shunsuke Nozawa, Hiroshi Sekiguchi, Masahiro Kuramochi, Yuji C. Sasaki
Publikováno v:
Membranes, Vol 13, Iss 8, p 708 (2023)
The transient receptor potential vanilloid type 1 (TRPV1) is a multimodal receptor which responds to various stimuli, including capsaicin, protons, and heat. Recent advances in cryo-electron microscopy have revealed the structures of TRPV1. However,
Externí odkaz:
https://doaj.org/article/66186bc20f344ab89a24b7591ee82655
Autor:
Koichiro Oishi, Mayu Nagamori, Yasuhiro Kashino, Hiroshi Sekiguchi, Yuji C. Sasaki, Atsuo Miyazawa, Yuri Nishino
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12069 (2023)
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that play an important role in signal transduction at the neuromuscular junction (NMJ). Movement of the nAChR extracellular domain following agonist binding induces conformation
Externí odkaz:
https://doaj.org/article/6766e9e6070146bc817b3e1126f29779
Autor:
Masahiro Kuramochi, Yige Dong, Yue Yang, Tatsuya Arai, Rio Okada, Yoichi Shinkai, Motomichi Doi, Kouki Aoyama, Hiroshi Sekiguchi, Kazuhiro Mio, Sakae Tsuda, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101224- (2022)
The dynamic properties of protein molecules are involved in the relationship between their structure and function. Time-resolved X-ray observation enables capturing the structures of biomolecules with picometre-scale precision. However, this techniqu
Externí odkaz:
https://doaj.org/article/d51b7b0d33ea4dc7a01a263f0631b0b5