Zobrazeno 1 - 5
of 5
pro vyhledávání: '"diagnostic imaging [Amyloidosis]"'
Autor:
Franz-Josef Gildehaus, Finn Peters, Nathalie L. Albert, Florian Eckenweber, Jochen Herms, Carmelo Sgobio, Barbara von Ungern-Sternberg, Axel Rominger, Leonie Beyer, Irena Brzak, Takaomi C. Saido, Christian Sacher, Maximilian Deussing, Marcus Unterrainer, Tanja Blume, Peter Bartenstein, Matthias Brendel, Ulf Neumann, Takashi Saito, Simon Lindner
Publikováno v:
J Nucl Med
Journal of nuclear medicine 60(12), 1787-1793 (2019). doi:10.2967/jnumed.119.227322
Journal of nuclear medicine 60(12), 1787-1793 (2019). doi:10.2967/jnumed.119.227322
Nonphysiologic overexpression of amyloid-β (Aβ) precursor protein in common transgenic Aβ mouse models of Alzheimer disease likely hampers their translational potential. The novel App(NL-G-F) mouse incorporates a mutated knock-in, potentially pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eebc307cff3deca8693cd3c0dbbbde5
https://doi.org/10.2967/jnumed.119.227322
https://doi.org/10.2967/jnumed.119.227322
Autor:
Annus, Tiina, Wilson, Liam R., Acosta-Cabronero, Julio, Cardenas-Blanco, Arturo, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Menon, David K., Zaman, Shahid H., Holland, Anthony J., Nestor, Peter J.
Publikováno v:
Neurobiology of aging 53, 11-19 (2017). doi:10.1016/j.neurobiolaging.2017.01.009
Neurobiology of Aging
Neurobiology of Aging
People with Down syndrome (DS) have a neurodevelopmentally distinct brain and invariably developed amyloid neuropathology by age 50. This cross-sectional study aimed to provide a detailed account of DS brain morphology and the changes occuring with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::63b7e55f23abc0a336807769911cf737
Autor:
Matthias Brendel, Franz-Josef Gildehaus, Finn Peters, Maximilian Deussing, Simon Lindner, Jochen Herms, Tanja Blume, Carola Focke, Laurence Ozmen, Nathalie L. Albert, Barbara von Ungern-Sternberg, Karlheinz Baumann, Peter Bartenstein, Axel Rominger
Publikováno v:
Journal of Neuroinflammation
Journal of neuroinflammation 15(1), 307 (2018). doi:10.1186/s12974-018-1347-6
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Blume, Tanja; Focke, Carola; Peters, Finn; Deussing, Maximilian; Albert, Nathalie L.; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Ozmen, Laurence; Baumann, Karlheinz; Bartenstein, Peter; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2018). Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. Journal of neuroinflammation, 15(1), p. 307. BioMed Central 10.1186/s12974-018-1347-6
Journal of neuroinflammation 15(1), 307 (2018). doi:10.1186/s12974-018-1347-6
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Blume, Tanja; Focke, Carola; Peters, Finn; Deussing, Maximilian; Albert, Nathalie L.; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Ozmen, Laurence; Baumann, Karlheinz; Bartenstein, Peter; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2018). Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. Journal of neuroinflammation, 15(1), p. 307. BioMed Central 10.1186/s12974-018-1347-6
Background Causal associations between microglia activation and β-amyloid (Aβ) accumulation during the progression of Alzheimer’s disease (AD) remain a matter of controversy. Therefore, we used longitudinal dual tracer in vivo small animal positr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371fc94c8eb860b8e0e97090cb981188
https://doi.org/10.1186/s12974-018-1347-6
https://doi.org/10.1186/s12974-018-1347-6
Autor:
Franz-Josef Gildehaus, Felix Overhoff, Karlheinz Baumann, Viktoria Korzhova, Anna Jaworska, Simon Lindner, Nathalie L. Albert, Axel Rominger, Roswitha Beck, Jochen Herms, Christian Haass, Peter Bartenstein, Federico Probst, Gernot Kleinberger, Matthias Brendel
Publikováno v:
Journal of nuclear medicine 57(6), 954-960 (2016). doi:10.2967/jnumed.115.167858
Amyloid imaging by small-animal PET in models of Alzheimer disease (AD) offers the possibility to track amyloidogenesis and brain energy metabolism. Because microglial activation is thought to contribute to AD pathology, we undertook a triple-tracer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a227b884f25c31324b3fe3521c7bce2
https://pubmed.ncbi.nlm.nih.gov/26912428
https://pubmed.ncbi.nlm.nih.gov/26912428
Autor:
Wang, Fen, Gordon, Brian A, McDade, Eric, Ringman, John M, Graff-Radford, Neill R, Ghetti, Bernardino, Farlow, Martin R, Sperling, Reisa, Salloway, Steve, Schofield, Peter R, Masters, Colin L, Martins, Ralph N, Ryman, Davis C, Rossor, Martin N, Jucker, Mathias, Danek, Adrian, Förster, Stefan, Lane, Christopher A S, Morris, John C, Benzinger, Tammie L S, Bateman, Randall J, Network, Dominantly Inherited Alzheimer, Ma, Shengmei, Xiong, Chengjie, Hassenstab, Jason, Goate, Alison, Fagan, Anne M, Cairns, Nigel J, Marcus, Daniel S
Publikováno v:
Neurology 85(9), 790-798 (2015). doi:10.1212/WNL.0000000000001903
Objective: To investigate the associations of cerebral amyloidosis with concurrent cognitive performance and with longitudinal cognitive decline in asymptomatic and symptomatic stages of autosomal dominant Alzheimer disease (ADAD). Methods: Two hundr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21579dcab61c7838b17acc56b1b42d8
https://pubmed.ncbi.nlm.nih.gov/26245927
https://pubmed.ncbi.nlm.nih.gov/26245927