Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities: results of an international, retrospective study

Autor: Christelle Dufour, Johannes Gojo, Sandra Jacobs, Barry Pizer, Dominik Sturm, Torsten Pietsch, Stefan Rutkowski, Christine Haberler, Nicolas U. Gerber, Teresa de Rojas, Peter Hauser, Ulrich Schüller, Peter C. Burger, Marta Perek-Polnik, Martin Mynarek, Jaeho Cho, Matija Snuderl, Bernward Zeller, Michal Zapotocky, Maura Massimino, Robert Kwiecien, Dominique Figarella-Branger, Andrey Golanov, Charles G. Eberhart, Stefan M. Pfister, Daniel Alderete, Thomas S. Jacques, Ella Kumirova, Konstantin Okonechnikov, Astrid Sehested, Ofelia Cruz, Andrey Korshunov, Björn Ole Juhnke, Niels Bovenschen, Jessica C Pickles, David Sumerauer, Cynthia Hawkins, David Scheie, Eugene Hwang, Pieter Wesseling, Barbara von Zezschwitz, Felice Giangaspero, Marcel Kool, Elizabeth Schepke, Andreas von Deimling, Marco Gessi, Dannis G. van Vuurden, Maximilian Wechsung, Miklós Garami, David Capper, Katja von Hoff, Maria Joao Gil-da-Costa, Maria Łastowska, Felix Schmitt-Hoffner, Olga Zheludkova, Lucas Moreno, Michael A. Grotzer, Frank Konietschke, Marina Ryzhova, Elisabeth J. Rushing, Irene Slavc

Publikováno v: Neuro-Oncology 23(9), 1597-1611 (2021). doi:10.1093/neuonc/noab136
Neuro-Oncology
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Neuro-Oncology, Oxford University Press (OUP), 2021, ⟨10.1093/neuonc/noab136⟩
Neuro-Oncology, 23(9), 1597-1611. Oxford University Press
von Hoff, K, Haberler, C, Schmitt-Hoffner, F, Schepke, E, de Rojas, T, Jacobs, S, Zapotocky, M, Sumerauer, D, Perek-Polnik, M, Dufour, C, van Vuurden, D, Slavc, I, Gojo, J, Pickles, J C, Gerber, N U, Massimino, M, Gil-da-Costa, M J, Garami, M, Kumirova, E, Sehested, A, Scheie, D, Cruz, O, Moreno, L, Cho, J, Zeller, B, Bovenschen, N, Grotzer, M, Alderete, D, Snuderl, M, Zheludkova, O, Golanov, A, Okonechnikov, K, Mynarek, M, Juhnke, B O, Rutkowski, S, Schüller, U, Pizer, B, von Zezschwitz, B, Kwiecien, R, Wechsung, M, Konietschke, F, Hwang, E I, Sturm, D, Pfister, S M, von Deimling, A, Rushing, E J, Ryzhova, M, Hauser, P, Łastowska, M, Wesseling, P, Giangaspero, F, Hawkins, C, Figarella-Branger, D, Eberhart, C, Burger, P, Gessi, M, Korshunov, A, Jacques, T S, Capper, D, Pietsch, T & Kool, M 2021, ' Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities : Results of an international, retrospective study ', Neuro-Oncology, vol. 23, no. 9, pp. 1597-1611 . https://doi.org/10.1093/neuonc/noab136
Neuro Oncol
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Neuro-Oncology, 2021, ⟨10.1093/neuonc/noab136⟩

Background Only few data are available on treatment-associated behavior of distinct rare CNS embryonal tumor entities previously treated as “CNS-primitive neuroectodermal tumors” (CNS-PNET). Respective data on specific entities, including CNS neu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfda65d63cf766e727aec652e64d395

Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients

Autor: Radke, Josefine, Koch, Arend, Pritsch, Fabienne, Schumann, Elisa, Misch, Martin, Hempt, Claudia, Lenz, Klaus, Löbel, Franziska, Paschereit, Fabienne, Heppner, Frank L., Vajkoczy, Peter, Koll, Randi, Onken, Julia

Publikováno v: Acta Neuropathologica Communications 7(1), 89 (2019). doi:10.1186/s40478-019-0745-z
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)

Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise predictive cutoff values to distinguish “MGMT methylated” from “MGMT unmethylated” pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d81c40d03e1c6a9208450ced4bbfcc6

Diesterified Derivatives of 5-Iodo-2′-Deoxyuridine as Cerebral Tumor Tracers

Autor: Oscar Arias-Carrión, Nils Freundlieb, Candan Depboylu, Thomas W. Rösler, Günter U. Höglinger, Damiano Librizzi, Wolfgang H. Oertel, Andreas Matusch, Helmut Hoeffken

Publikováno v: PLoS one 9(7), e102397 (2014). doi:10.1371/journal.pone.0102397
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e102397 (2014)
PLOS ONE 9(7), e102397 (2014). doi:10.1371/journal.pone.0102397

With the aim to develop beneficial tracers for cerebral tumors, we tested two novel 5-iodo-2'-deoxyuridine (IUdR) derivatives, diesterified at the deoxyribose residue. The substances were designed to enhance the uptake into brain tumor tissue and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9492ef2f54da4dc13da7865c9317c6
https://hdl.handle.net/2128/8721