Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

Autor: Giusy Sala, Riccardo Ghidoni, Monica Thelestam, Stuart E.H. Moore, Christelle Durrant, Jana I. Fuehring, Agnès Rötig, Alexandra Willemetz, Abram Katz, D Chretien, Myriam Ermonval

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6, p 2028 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩
Volume 21
Issue 6
International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩

UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase. Chinese hamster lu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfe91ea1573ac5fc8e267238aae14a8
https://www.mdpi.com/1422-0067/21/6/2028