Zobrazeno 1 - 10
of 34
pro vyhledávání: '"destabilization of the medial meniscus (DMM)"'
Autor:
Jingting Xu, Zhaoxuan Ruan, Zhou Guo, Liangcai Hou, Genchun Wang, Zehang Zheng, Xiong Zhang, Haigang Liu, Kai Sun, Fengjing Guo
Publikováno v:
Bone & Joint Research, Vol 13, Iss 3, Pp 110-123 (2024)
Aims: Osteoarthritis (OA) is the most common chronic pathema of human joints. The pathogenesis is complex, involving physiological and mechanical factors. In previous studies, we found that ferroptosis is intimately related to OA, while the role of S
Externí odkaz:
https://doaj.org/article/bd074a90b237484faa68f1ebdcacbd21
Autor:
Hua Zhang, Jie Li, Xiaobing Xiang, Bengen Zhou, Changqing Zhao, Qiushi Wei, Youqiang Sun, Jianfa Chen, Boyong Lai, Zequan Luo, Aihua Li
Publikováno v:
Bone & Joint Research, Vol 10, Iss 11, Pp 704-713 (2021)
Aims: Tert-butylhydroquinone (tBHQ) has been identified as an inhibitor of oxidative stress-induced injury and apoptosis in human neural stem cells. However, the role of tBHQ in osteoarthritis (OA) is unclear. This study was carried out to investigat
Externí odkaz:
https://doaj.org/article/ec12cef9b5944ccfb9b167cbd83357f4
Publikováno v:
Bone & Joint Research, Vol 10, Iss 8, Pp 548-557 (2021)
Aims: MicroRNA-183 (miR-183) is known to play important roles in osteoarthritis (OA) pain. The aims of this study were to explore the specific functions of miR-183 in OA pain and to investigate the underlying mechanisms. Methods: Clinical samples wer
Externí odkaz:
https://doaj.org/article/60bc70cdfc8a4733948778c039435ef5
Publikováno v:
Heliyon, Vol 7, Iss 9, Pp e07906- (2021)
Pain due to osteoarthritis (OA) often occurs during locomotion in the vertical direction when joints are subjected to high mechanical load, e.g. during standing up from a chair or using stairs. To investigate joint pain in OA rat models, dynamic weig
Externí odkaz:
https://doaj.org/article/17745b58bc6b4fe2bc53e0f0d792df81
Publikováno v:
International Journal of Nanomedicine, Vol Volume 13, Pp 1215-1224 (2018)
Hongsik Cho,1,2,* Byoung Ju Kim,3,4,* Sang-Hyug Park,5 Karen A Hasty,1,2 Byoung-Hyun Min3,4,6 1Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center–Campbell Clinic, 2Veterans Affairs Medical Ce
Externí odkaz:
https://doaj.org/article/c721059b6aac48c3bd140801484c9581
Autor:
Yusuke Kunieda, Takayuki Okumo, Hideshi Ikemoto, Naoki Adachi, Midori Tanaka, Taro Kimura, Kanako Yusa, Koji Kanzaki, Masataka Sunagawa
Publikováno v:
Applied Sciences, Vol 11, Iss 18, p 8421 (2021)
Boiogito (BO), a Japanese traditional herbal medicine, has been proven to be clinically effective against knee osteoarthritis (KOA)-associated pain. However, the therapeutic mechanism of BO remains unclear. Thus, we investigated the analgesic mechani
Externí odkaz:
https://doaj.org/article/c6f4fb62aa3d4820992ea6b6e73b58d9
Publikováno v:
Bone & Joint Research, Vol 10, Iss 8, Pp 548-557 (2021)
Bone & Joint Research
Bone & Joint Research
AimsMicroRNA-183 ( miR-183) is known to play important roles in osteoarthritis (OA) pain. The aims of this study were to explore the specific functions of miR-183 in OA pain and to investigate the underlying mechanisms.MethodsClinical samples were co
Autor:
Masataka Sunagawa, Naoki Adachi, Takayuki Okumo, Midori Tanaka, Kanako Yusa, Taro Kimura, Yusuke Kunieda, Koji Kanzaki, Hideshi Ikemoto
Publikováno v:
Applied Sciences
Volume 11
Issue 18
Applied Sciences, Vol 11, Iss 8421, p 8421 (2021)
Volume 11
Issue 18
Applied Sciences, Vol 11, Iss 8421, p 8421 (2021)
Boiogito (BO), a Japanese traditional herbal medicine, has been proven to be clinically effective against knee osteoarthritis (KOA)-associated pain. However, the therapeutic mechanism of BO remains unclear. Thus, we investigated the analgesic mechani
Publikováno v:
Heliyon
Heliyon, Vol 7, Iss 9, Pp e07906-(2021)
Heliyon, Vol 7, Iss 9, Pp e07906-(2021)
Pain due to osteoarthritis (OA) often occurs during locomotion in the vertical direction when joints are subjected to high mechanical load, e.g. during standing up from a chair or using stairs. To investigate joint pain in OA rat models, dynamic weig
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8911, p 8911 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 8911, p 8911 (2020)
Adipose-derived mesenchymal stromal cells (Ad-MSCs) are a promising tool for articular cartilage repair and regeneration. However, the terminal hypertrophic differentiation of Ad-MSC-derived cartilage is a critical barrier during hyaline cartilage re