Výsledky vyhledávání - "desmuramyl peptide"

Akademický článek

Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides

Autor: Rosana Ribić, Ranko Stojković, Lidija Milković, Mariastefania Antica, Marko Cigler, Srđanka Tomić

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1805-1814 (2019)

Muramyl dipeptide is the minimal structure of peptidoglycan with adjuvant properties. Replacement of the N-acetylmuramyl moiety and increase of lipophilicity are important approaches in the preparation of muramyl dipeptide analogues with improved pha

Externí odkaz: https://doaj.org/article/d5f751ed62dc4d94b67f598b5d9d2502

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Akademický článek

Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole

Autor: Vesna Petrović Peroković, Željka Car, Josip Draženović, Ranko Stojković, Lidija Milković, Mariastefania Antica, Đani Škalamera, Srđanka Tomić, Rosana Ribić

Publikováno v: Molecules, Vol 26, Iss 21, p 6352 (2021)

Muramyl dipeptide (MDP) is the smallest peptidoglycan fragment able to trigger the immune response. Structural modification of MDP can lead to the preparation of analogs with improved immunostimulant properties, including desmuramyl peptides (DMPs).

Externí odkaz: https://doaj.org/article/9b803ac093d84ef5b36854a56efc2aa2

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Sinteza diamidnog derivata disupstituiranog ferocena s desmuramil-peptidnom i manoznom podjedinicom

Autor: Bliznac, Matias

U sklopu ovog diplomskog rada razvijen je sintetski put priprave amidnih, disupstituiranih ferocenskih derivata s desmuramil-peptidnom (DMP) i manoznom podjedinicom. Derivati se međusobno razlikuju u broju metilenskih skupina (n = 0-4) na poveznici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::390c4b80a6c6debdb2366090757dd2c3
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:11588

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Preparation of diamide derivatives of a disubstituted ferrocene with desmuramyl peptide and mannose subunit

Autor: Car, Željka, Bliznac, Matias, Petrović Peroković, Vesna, Kovačević, Monika, Ribić, Rosana, Barišić, Lidija

Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D- isoglutamine, MDP) is the smallest structural unit of peptidoglycans showing immunostimulating activity. [1] MDP analogues without the hydrophilic N-acetylmuramyl moiety are called desmuramyl peptides (D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::59dcb6fe7cc65212c4dd603f9033b3bb
https://www.bib.irb.hr/1265153

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Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents

Autor: Vesna Petrović Peroković, Željka Car, Mia Bušljeta, Danijela Mihelec, Marija Paurević, Siniša Ivanković, Ranko Stojković, Rosana Ribić

Publikováno v: International journal of molecular sciences
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8628

Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest peptidoglycan fragment able to trigger an immune response by activating the NOD2 receptor. Structural modification of MDP can lead to analogues with improved immunostimu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8602b42b1ec55c67669763fb17983141
https://pubmed.ncbi.nlm.nih.gov/35955759

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Design, synthesis and evaluation of immunostimulating activities of mannosylated desmuramyl peptides containing lipophilic substituents

Autor: Mihelec, Danijela, Car, Željka, Petrović Peroković, Vesna, Stojković, Ranko, Ribić, Rosana

Muramyl dipeptide (MDP, N-acetylmuramyl-L-alanyl- D-isoglutamine) is the smallest peptidoglycan fragment capable to trigger the immune response. MDP acts as a pathogen-associated molecular pattern and activates the NOD2 (Nucleotide Binding Oligomeriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6aee01605d817c4ef776ede025e2ab3a
https://www.bib.irb.hr/1233666

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Design and synthesis of mannosylated ferrocene derivatives of desmuramyl peptides

Autor: Ribić, Rosana, Petrović Peroković, Vesna, Car, Željka, Kovačević, Monika, Barišić, Lidija

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6cc1272175d4e63b3545555208ea95d9
https://www.bib.irb.hr/1278849

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Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole

Autor: Srđanka Tomić, Đani Škalamera, Josip Draženović, Željka Car, Rosana Ribić, Lidija Milkovic, Ranko Stojković, Vesna Petrović Peroković, Mariastefania Antica

Publikováno v: Molecules, Vol 26, Iss 6352, p 6352 (2021)
Molecules
Volume 26
Issue 21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb355381bc63bb1883f27d7fdc957ec
https://www.mdpi.com/1420-3049/26/21/6352

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Akademický článek

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Mannosylated adamantane-containing desmuramyl peptide recognition by the NOD2 receptor: a molecular dynamics study

Autor: Rosana Ribić, Aleksandra Maršavelski, Marija Paurević

Publikováno v: Organicbiomolecular chemistry. 19(32)

Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular receptor that recognizes the bacterial peptidoglycan fragment, muramyl dipeptide (MDP). Our group has synthesized and biologically evaluated desmuramyl peptides containing adamant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3582fec21fff37defc935d6dc1f72a5d
https://pubmed.ncbi.nlm.nih.gov/34095941

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