Výsledky vyhledávání - "desmuramyl dipeptide"

Synthesys of ferrocene amides of mannosylated desmuramyl dipeptide with potential adjuvant activity

Autor: Bajan, Ivona

U sklopu ovog rada sintetizirana su tri ferocenska amidna derivata manoziliranog desmuramildipeptida s varirajućom duljinom ugljikovodičnog lanca između ferocena i ostatka molekule. Ferocenski amini s tri i četiri metilenske skupine pripravljeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3908::231477ded2024e24dc6bfd26048634e7
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:10814/datastream/PDF

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Synthesis of ferrocene esters of mannosylated desmuramyl dipeptide

Autor: Grgurić, Dora

U sklopu diplomskog rada opisana je priprava triju ferocenskih estera manoziliranog desmuramil-dipeptida, L-Ala-D-isoGln. Konvergentnim pristupom sintezi najprije su zasebno pripravljena tri fragmenta: manozna podjedinica s razmaknicom od dva atoma u

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https://repozitorij.pmf.unizg.hr/islandora/object/pmf:10842/datastream/PDF

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Preparation of aliphatic triazole derivatives of mannosylated desmuramyl dipeptide

Autor: Bušljeta, Mia

U sklopu diplomskog rada opisana je priprava triju novih alifatskih triazolnih derivata manoziliranog desmuramil-dipeptida, L-Ala-D-isoGln. U konvergentnom pristupu sintezi zasebno su pripravljene tri podjedinice: dipeptid, alifatski triazolni amin i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::953aa2677cce9cdffedf0a87da404e2b
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:10386

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SYNTHESIS OF MANNOSYLATED FERROCENE ESTER DERIVATIVES OF DESMURAMYL DIPEPTIDE

Autor: Petrović Peroković, Vesna, Car, Željka, Grgurić, Dora, Ribić, Rosana, Kovačević, Monika, Barišić, Lidija

Immune adjuvants are added to vaccines in order to enhance the immune response to an antigen. Muramyl dipeptide (MDP, N-acetylmuramyl-L-alanyl-D- isoglutamine) is the smallest peptidoglycan fragment able to trigger the immune response.[1] Structural

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https://www.bib.irb.hr/1205423

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Isolation and derivatization of saponin from Quillaja saponaria tree bark for the synthesis of a conjugate with desmuramyl dipeptide

Autor: Škalamera, Đani, Logožar, Ivan

Natural compounds are of particular interest in the development of new vaccine adjuvants. Saponins isolated from the bark of the Quillaja saponaria (QS) Molina tree have proven to be one of the strongest immunoadjuvants known to date. The lead compou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::85738c662182f0afad55aeef75339fc9
https://www.bib.irb.hr/1181859

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Akademický článek

Physicochemical and preclinical pharmacokinetic and toxicological evaluation of LK-423—a new phthalimido-desmuramyl-dipeptide derivative with immunomodulating activity.

Autor: Smrdel, Polona^1,2 (AUTHOR), Grabnar, Iztok² (AUTHOR), Locatelli, Igor² (AUTHOR), Černe, Manica¹ (AUTHOR), Andrenšek, Samo¹ (AUTHOR), Kovačič, Nataša³ (AUTHOR), Kristl, Albin² (AUTHOR), Bogataj, Marija² (AUTHOR), Urleb, Uroš^1,2 (AUTHOR), Mrhar, Aleš² (AUTHOR) ales.mrhar@ffa.uni-lj.si

Publikováno v: Drug Development & Industrial Pharmacy. Nov2009, Vol. 35 Issue 11, p1293-1304. 12p. 1 Diagram, 4 Charts, 4 Graphs.

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Synthesis of new amphiphilic triazole derivatives of mannosylated desmuramyl dipeptide

Autor: Mihelec, Danijela, Bušljeta, Mia, Car, Željka, Petrović Peroković, Vesna, Ribić, Rosana

Adjuvants or immunostimulators are substances that are added to vaccines to improve the specific human immune response to a specific antigen. Derivatives of muramyl dipeptide (MDP, N- acetylmuramyl-L-alanyl-D-isoglutamine) as well as desmuramyl dipep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::b28f8f527f8df7c939949062142b53dc
https://www.bib.irb.hr/1162483

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Synthesis of a Potential Vaccine Adjuvant - Conjugate of Quillaja Saponin and Desmuramyl Dipeptide

Autor: Biškup, Andrej, Škalamera, Đani

Adjuvanti su tvari koje se dodaju cjepivima kako bi se pojačao imunološki odgovor na antigen. Najčešće korišteni adjuvanti su alum, koloidna suspenzija aluminijevog hidroksida, i MF50, emulzija skvalena u vodi. Vrlo je mali broj dostupnih adjuv

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https://www.bib.irb.hr/1052349

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Akademický článek

Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium-induced colitis in rodents through restoring their interleukin-10 producing capacity.

Autor: Moriguchi M; Institute of Research and Development, Fujimoto Pharmaceutical Corporation, Osaka, Japan., Urabe K, Norisada N, Ochi C, Stalc A, Urleb U, Muraoka S

Publikováno v: Arzneimittel-Forschung [Arzneimittelforschung] 1999 Feb; Vol. 49 (2), pp. 184-92.

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Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium-induced colitis in rodents through restoring their interleukin-10 producing capacity

Autor: M, Moriguchi, K, Urabe, N, Norisada, C, Ochi, A, Stalc, U, Urleb, S, Muraoka

Publikováno v: Arzneimittel-Forschung. 49(2)

A new phthalimido compound, N-[2-(2-phthalimidoethoxy)acetyl]-L-alanyl-D-glutamic acid (CAS 142489-47-2, LK 423), was examined for its possible activity to modulate levels and species of cytokines in mice carrying a specific inflamed organ. Colonic i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12ed18bad664320d78586f5a33eebbcf
https://pubmed.ncbi.nlm.nih.gov/10083986

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